PMID- 30683627
OWN - NLM
STAT- MEDLINE
DCOM- 20210524
LR  - 20210524
IS  - 1995-9133 (Electronic)
IS  - 1684-1182 (Linking)
VI  - 53
IP  - 5
DP  - 2020 Oct
TI  - Nut sensitization profile in Southern Taiwan.
PG  - 791-796
LID - S1684-1182(18)30149-X [pii]
LID - 10.1016/j.jmii.2018.12.005 [doi]
AB  - BACKGROUND/PURPOSE: To evaluate the relationship between serum-specific 
      immunoglobulin E (IgE) to peanuts/tree nuts and their clinical manifestations in 
      atopic diseases. METHOD: Serum from people with the classical symptoms of asthma, 
      allergic rhinitis (AR), or atopic dermatitis (AD) was collected for the 
      measurement of serum-specific IgE to peanuts, cashew nuts, Brazil nuts, almonds, 
      and coconuts. Cases with possible sensitization to these nuts (serum specific 
      IgE >== 0.35 kU/L) were selected and their clinical relationships with 
      physician-diagnosed asthma, allergic rhinitis, or atopic dermatitis were 
      analyzed. RESULT: Compared with non-sensitization group, people with peanut/tree 
      nut sensitization have higher prevalence of atopic dermatitis, but no such 
      difference noted in the prevalence of allergic rhinitis. In the situation of 
      asthma, people with sensitization to peanuts and Brazil nuts, but not other nuts, 
      have higher prevalence of asthma than people without sensitization to any nut 
      (p < 0.001 and p < 0.05, respectively). Binary logistic regression analysis also 
      showed positive associations between peanut (OR: 1.164, p value = 0.017) and 
      Brazil nut (OR: 1.304, p value = 0.055) sensitization and asthma. The 
      associations between peanut and Brazil nut sensitization and asthma were 
      independent of the prevalence of other atopic diseases. CONCLUSION: People in 
      Asia may have less severe allergic effects as in Western countries, but 
      sensitization to specific food allergens such as peanuts or Brazil nuts may 
      predispose individuals to asthma, which could be helpful in diagnosis and 
      deserves more attention than previously considered.
CI  - Copyright (c) 2019. Published by Elsevier B.V.
FAU - Cheng, Chih-Wei
AU  - Cheng CW
AD  - Department of Pediatrics, Kaohsiung Veterans General Hospital, Number 386, 
      Dazhong 1st Road, Zuoying District, Kaohsiung City 813, Taiwan. Electronic 
      address: laienhata@gmail.com.
FAU - Lin, Yung-Chih
AU  - Lin YC
AD  - Department of Pediatrics, Taipei Veterans General Hospital, Taitung Branch, 
      Taitung, Taiwan.
FAU - Nong, Bao-Ren
AU  - Nong BR
AD  - Department of Pediatrics, Kaohsiung Veterans General Hospital, Number 386, 
      Dazhong 1st Road, Zuoying District, Kaohsiung City 813, Taiwan; Department of 
      Pediatrics, Tri-Service General Hospital, National Defense Medical Center, 
      Taipei, Taiwan.
FAU - Liu, Po-Yen
AU  - Liu PY
AD  - Department of Pediatrics, Kaohsiung Veterans General Hospital, Number 386, 
      Dazhong 1st Road, Zuoying District, Kaohsiung City 813, Taiwan.
FAU - Huang, Yung-Feng
AU  - Huang YF
AD  - Department of Pediatrics, Kaohsiung Veterans General Hospital, Number 386, 
      Dazhong 1st Road, Zuoying District, Kaohsiung City 813, Taiwan; Department of 
      Pediatrics, Tri-Service General Hospital, National Defense Medical Center, 
      Taipei, Taiwan; Wellem Medical Group, Hangzhou, China. Electronic address: 
      yf5012@hotmail.com.
FAU - Lu, Ling-Ying
AU  - Lu LY
AD  - Division of Allergy, Immunology and Rheumatology, Department of Medicine, 
      Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
FAU - Lee, Herng-Sheng
AU  - Lee HS
AD  - Department of Pathology and Laboratory, Kaohsiung Veterans General Hospital, 
      Kaohsiung, Taiwan.
LA  - eng
PT  - Journal Article
DEP - 20181227
PL  - England
TA  - J Microbiol Immunol Infect
JT  - Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
JID - 100956211
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Arachis/immunology
MH  - Asthma/epidemiology/immunology
MH  - Child
MH  - Child, Preschool
MH  - Dermatitis, Atopic
MH  - Female
MH  - Food Hypersensitivity/*epidemiology/*immunology
MH  - Humans
MH  - Immunoglobulin E/blood
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Nuts/*immunology
MH  - Retrospective Studies
MH  - Rhinitis
MH  - Taiwan
MH  - Young Adult
OTO - NOTNLM
OT  - Asthma
OT  - Atopic diseases
OT  - Brazil nut sensitization
OT  - Peanut sensitization
OT  - Specific IgE
EDAT- 2019/01/27 06:00
MHDA- 2021/05/25 06:00
CRDT- 2019/01/27 06:00
PHST- 2018/05/27 00:00 [received]
PHST- 2018/11/21 00:00 [revised]
PHST- 2018/12/12 00:00 [accepted]
PHST- 2019/01/27 06:00 [pubmed]
PHST- 2021/05/25 06:00 [medline]
PHST- 2019/01/27 06:00 [entrez]
AID - S1684-1182(18)30149-X [pii]
AID - 10.1016/j.jmii.2018.12.005 [doi]
PST - ppublish
SO  - J Microbiol Immunol Infect. 2020 Oct;53(5):791-796. doi: 
      10.1016/j.jmii.2018.12.005. Epub 2018 Dec 27.