PMID- 30685060
OWN - NLM
STAT- MEDLINE
DCOM- 20200102
LR  - 20220302
IS  - 1365-229X (Electronic)
IS  - 0009-9260 (Linking)
VI  - 74
IP  - 3
DP  - 2019 Mar
TI  - Arrhythmogenic right ventricular cardiomyopathy (ARVC) mimics: the knot 
      unravelled by cardiovascular MRI.
PG  - 228-234
LID - S0009-9260(18)30613-5 [pii]
LID - 10.1016/j.crad.2018.12.002 [doi]
AB  - AIM: To assess the role of cardiovascular magnetic resonance imaging (CMRI) in 
      patients referred for suspected arrhythmogenic right ventricular cardiomyopathy 
      (ARVC), its ability to identify ARVC mimics, and subsequent clinical impact. 
      MATERIALS AND METHODS: The CMRI registry of the year 2014 was analysed to 
      identify all consecutive patients referred for suspected ARVC. A comprehensive 
      CMRI protocol that included anatomy, bi-ventricular function modules, and late 
      gadolinium enhancement (LGE) was performed in all patients. RESULTS: Out of 2,481 
      CMRI performed, 124 patients (5%) were referred for suspected ARVC. A 
      pathological substrate was identified at CMRI in 36 patients (29%): five patients 
      (4%) had ischaemic heart disease (IHD) and 10 (8%) non-IHD; five patients (4%) 
      met CMRI criteria for ARVC and 16 (13%) were ARVC mimics. right ventricular 
      end-diastolic volume (RVEDV) and right ventricular stroke volume (RVSV) were 
      significantly higher in patients with ARVC mimics (RVEDV p=0.007, RVSV p=0.012) 
      and ARVC (RVEDV p=0.013, RVSV p=0.013), as compared to those with structurally 
      normal hearts. CMRI was superior to echocardiography in the identification of 
      ARVC mimics (13% versus 1%, p=0.01). CONCLUSIONS: CMRI was able to identify 16 
      (13%) ARVC mimics, from congenital abnormalities to acquired heart disease. CMRI 
      was superior in identifying ARVC mimics compared to echocardiography, and overall 
      provided a change in diagnosis in 22% of patients.
CI  - Copyright (c) 2018. Published by Elsevier Ltd.
FAU - Amadu, A M
AU  - Amadu AM
AD  - Bristol Heart Institute, Bristol NIHR Cardiovascular Biomedical Research Unit 
      (BRU), University of Bristol, UK.
FAU - Baritussio, A
AU  - Baritussio A
AD  - Bristol Heart Institute, Bristol NIHR Cardiovascular Biomedical Research Unit 
      (BRU), University of Bristol, UK.
FAU - Dastidar, A G
AU  - Dastidar AG
AD  - Bristol Heart Institute, Bristol NIHR Cardiovascular Biomedical Research Unit 
      (BRU), University of Bristol, UK.
FAU - De Garate, E
AU  - De Garate E
AD  - Bristol Heart Institute, Bristol NIHR Cardiovascular Biomedical Research Unit 
      (BRU), University of Bristol, UK.
FAU - Rodrigues, J C L
AU  - Rodrigues JCL
AD  - Bristol Heart Institute, Bristol NIHR Cardiovascular Biomedical Research Unit 
      (BRU), University of Bristol, UK; Department of Radiology, Royal United Hospitals 
      NHS Foundation Trust, Combe Park, Bath, BA1 3NG, UK.
FAU - Biglino, G
AU  - Biglino G
AD  - Bristol Heart Institute, Bristol NIHR Cardiovascular Biomedical Research Unit 
      (BRU), University of Bristol, UK.
FAU - Lyen, S
AU  - Lyen S
AD  - Bristol Heart Institute, Bristol NIHR Cardiovascular Biomedical Research Unit 
      (BRU), University of Bristol, UK.
FAU - Diab, I
AU  - Diab I
AD  - Bristol Heart Institute, Bristol NIHR Cardiovascular Biomedical Research Unit 
      (BRU), University of Bristol, UK.
FAU - Duncan, E
AU  - Duncan E
AD  - Bristol Heart Institute, Bristol NIHR Cardiovascular Biomedical Research Unit 
      (BRU), University of Bristol, UK.
FAU - Nisbet, A
AU  - Nisbet A
AD  - Bristol Heart Institute, Bristol NIHR Cardiovascular Biomedical Research Unit 
      (BRU), University of Bristol, UK.
FAU - Thomas, G
AU  - Thomas G
AD  - Bristol Heart Institute, Bristol NIHR Cardiovascular Biomedical Research Unit 
      (BRU), University of Bristol, UK.
FAU - Angelini, G D
AU  - Angelini GD
AD  - Bristol Heart Institute, Bristol NIHR Cardiovascular Biomedical Research Unit 
      (BRU), University of Bristol, UK.
FAU - Bucciarelli-Ducci, C
AU  - Bucciarelli-Ducci C
AD  - Bristol Heart Institute, Bristol NIHR Cardiovascular Biomedical Research Unit 
      (BRU), University of Bristol, UK. Electronic address: 
      c.bucciarelli-ducci@bristol.ac.uk.
LA  - eng
GR  - CH/1992027/7163/BHF_/British Heart Foundation/United Kingdom
PT  - Journal Article
DEP - 20190123
PL  - England
TA  - Clin Radiol
JT  - Clinical radiology
JID - 1306016
RN  - 0 (Contrast Media)
RN  - 0 (Organometallic Compounds)
RN  - 1BJ477IO2L (gadobutrol)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Arrhythmogenic Right Ventricular Dysplasia/*diagnostic imaging
MH  - Contrast Media
MH  - Diagnosis, Differential
MH  - Echocardiography
MH  - Electrocardiography
MH  - Female
MH  - Humans
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - Middle Aged
MH  - Organometallic Compounds
MH  - Registries
MH  - Retrospective Studies
EDAT- 2019/01/28 06:00
MHDA- 2020/01/03 06:00
CRDT- 2019/01/28 06:00
PHST- 2017/11/26 00:00 [received]
PHST- 2018/12/06 00:00 [accepted]
PHST- 2019/01/28 06:00 [pubmed]
PHST- 2020/01/03 06:00 [medline]
PHST- 2019/01/28 06:00 [entrez]
AID - S0009-9260(18)30613-5 [pii]
AID - 10.1016/j.crad.2018.12.002 [doi]
PST - ppublish
SO  - Clin Radiol. 2019 Mar;74(3):228-234. doi: 10.1016/j.crad.2018.12.002. Epub 2019 
      Jan 23.