PMID- 30693051 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 1878-5409 (Electronic) IS - 1878-5409 (Linking) VI - 19 IP - 1 DP - 2019 Jan TI - Coronary restenosis of in-stent protruding bump with rapid progression: Optical frequency domain imaging and angioscopic observation. PG - 12-14 LID - 10.1016/j.jccase.2018.08.010 [doi] AB - In-stent restenosis (ISR) remains a tough problem after percutaneous coronary intervention (PCI) despite advances in technology of drug-eluting stents (DES). A 63-year-old man undergoing hemodialysis was diagnosed with non-ST elevation acute coronary syndrome (NSTE-ACS). An emergency coronary angiography (CAG) revealed severe stenosis in the middle left circumflex artery (LCx). After pre-dilatation with non-compliant balloon, primary PCI was successfully performed with DES implantation. Four months after, CAG was performed again and verified ISR of LCx under diagnosis of recurrent NSTE-ACS. Subsequently multimodality intravascular imaging assessment was performed for the ISR lesion. Optical frequency domain imaging showed the eccentric protruding mass with irregular surface with high-backscatter, whereas angioscopy revealed the in-stent bump with yellow color. The ISR lesion was successfully treated by drug-coated balloon angioplasty. However, he suffered recurrent NSTE-ACS five months later. CAG revealed de novo stenotic lesions not only in re-restenosis of LCx but also in proximal left anterior descending artery and ostium of right coronary artery. He was scheduled to undergo coronary artery bypass grafting for three-vessel disease. Multimodality assessment is useful to diagnose the recurrent restenosis lesion with calcified nodule. . FAU - Kawai, Kenji AU - Kawai K AD - Division of Cardiovascular Medicine and Coronary Heart Disease, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8501, Japan. FAU - Akahori, Hirokuni AU - Akahori H AD - Division of Cardiovascular Medicine and Coronary Heart Disease, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8501, Japan. FAU - Imanaka, Takahiro AU - Imanaka T AD - Division of Cardiovascular Medicine and Coronary Heart Disease, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8501, Japan. FAU - Miki, Kojiro AU - Miki K AD - Division of Cardiovascular Medicine and Coronary Heart Disease, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8501, Japan. FAU - Yoshihara, Nagataka AU - Yoshihara N AD - Division of Cardiovascular Medicine and Coronary Heart Disease, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8501, Japan. FAU - Yanaka, Koji AU - Yanaka K AD - Division of Cardiovascular Medicine and Coronary Heart Disease, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8501, Japan. FAU - Masuyama, Tohru AU - Masuyama T AD - Division of Cardiovascular Medicine and Coronary Heart Disease, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8501, Japan. FAU - Ishihara, Masaharu AU - Ishihara M AD - Division of Cardiovascular Medicine and Coronary Heart Disease, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8501, Japan. LA - eng PT - Case Reports DEP - 20181015 PL - Japan TA - J Cardiol Cases JT - Journal of cardiology cases JID - 101549579 PMC - PMC6342683 OTO - NOTNLM OT - Coronary angioscopy OT - In-stent restenosis OT - Optical frequency domain imaging EDAT- 2019/01/30 06:00 MHDA- 2019/01/30 06:01 PMCR- 2018/10/15 CRDT- 2019/01/30 06:00 PHST- 2018/05/10 00:00 [received] PHST- 2018/07/18 00:00 [revised] PHST- 2018/08/17 00:00 [accepted] PHST- 2019/01/30 06:00 [entrez] PHST- 2019/01/30 06:00 [pubmed] PHST- 2019/01/30 06:01 [medline] PHST- 2018/10/15 00:00 [pmc-release] AID - S1878-5409(18)30086-0 [pii] AID - 10.1016/j.jccase.2018.08.010 [doi] PST - epublish SO - J Cardiol Cases. 2018 Oct 15;19(1):12-14. doi: 10.1016/j.jccase.2018.08.010. eCollection 2019 Jan.