PMID- 30695428
OWN - NLM
STAT- MEDLINE
DCOM- 20190327
LR  - 20190327
IS  - 1003-5370 (Print)
IS  - 1003-5370 (Linking)
VI  - 37
IP  - 1
DP  - 2017 Jan
TI  - [Effect of Acupoint Application Therapy of Summer Treatment for Winter Diseases 
      on Nerve-Endocrine-Immune Network System in Patient with Non-Acute Attack 
      Asthma].
PG  - 68-71
AB  - Objective To observe the effect of acupoint application therapy in summer to 
      treat winter diseases (abbreviated as AATSTWD) on nerve-endocrine-immune network 
      system in patients with non-acute attack asthma, and to study possible 
      mechanisms. Methods Fifty healthy volunteers were re- cruited as the normal 
      control group and 50 patients with non-acute attack asthma were recruited as the 
      asthma group. Patients in the normal control group received no intervention. 
      Those in the control group were treated with acupoint application therapy on hot 
      days (applied on the first day of three dog days, 3 times in total). Blood 
      samples were tested before treatment and after 3 times of application. The 
      contents of serum immunoglobulin E (IgE) , interleukin-4 (IL-4) , plasma 
      substance P (SP) , and vasoactive intes- tinal peptide (VIP) were detected using 
      radioimmunoassay. Contents of immunoglobulin A and G (IgA, IgG) were tested by 
      immunoturbidimetry. Content of interferon-y (INF-y) were tested by enzyme linked 
      immunosorbent assay. Results Compared with the normal control group, serum 
      contents of IgA, igG, IFN-y, and plasma VIP decreased, contents of IgE, IL-4, and 
      SP significantly increased in the asthma group before treatment (P <0. 05). 
      Compared with before treatment in the same group, serum contents of IgA, IgG, 
      VIP, and IFN-y increased, and contents of IgE, IL-4, and SP decreased in the 
      asthma group after treatment (P <0. 05). Conclusion Acupoint application therapy 
      in summer to treat winter diseases method could prevent and treat bronchial 
      asthma possibly through improving immune function, control- ling the release of 
      cytokines , and regulating neurotransmitters.
FAU - Ll, Bo-Lin
AU  - Ll BL
FAU - Wang, Ya-Li
AU  - Wang YL
FAU - Yang, Qian
AU  - Yang Q
FAU - Zhang, Ming-Quan
AU  - Zhang MQ
FAU - Wang, Xin-Guo
AU  - Wang XG
FAU - Yan, Cui-Huan
AU  - Yan CH
FAU - Shi, Xu-Liang
AU  - Shi XL
LA  - chi
PT  - Journal Article
PL  - China
TA  - Zhongguo Zhong Xi Yi Jie He Za Zhi
JT  - Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese 
      journal of integrated traditional and Western medicine
JID - 9211576
RN  - 0 (Immunoglobulin G)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - *Acupuncture Points
MH  - *Asthma/therapy
MH  - Humans
MH  - Immunity, Humoral
MH  - Immunoglobulin E
MH  - Immunoglobulin G
MH  - Seasons
EDAT- 2017/01/01 00:00
MHDA- 2017/01/01 00:01
CRDT- 2019/01/30 06:00
PHST- 2019/01/30 06:00 [entrez]
PHST- 2017/01/01 00:00 [pubmed]
PHST- 2017/01/01 00:01 [medline]
PST - ppublish
SO  - Zhongguo Zhong Xi Yi Jie He Za Zhi. 2017 Jan;37(1):68-71.