PMID- 30699167 OWN - NLM STAT- MEDLINE DCOM- 20191018 LR - 20200309 IS - 1932-6203 (Electronic) IS - 1932-6203 (Linking) VI - 14 IP - 1 DP - 2019 TI - Demand and supply factors of iron-folic acid supplementation and its association with anaemia in North Indian pregnant women. PG - e0210634 LID - 10.1371/journal.pone.0210634 [doi] LID - e0210634 AB - Anaemia prevalence in pregnant women of India declined from 57.9% to 50.3% from National Family Health Survey (NFHS)-3 to NFHS-4. However, over the course of that decade, the uptake of iron and folic acid (IFA) supplementation for 100 days of pregnancy improved by only 15%. To understand demand side risk factors of anaemia specifically related to IFA intake, an in-depth survey was conducted on pregnant women (n = 436) in 50 villages and wards of Sirohi district of Rajasthan, India. At the demand side, consistent IFA consumption in the previous trimester was inversely and strongly associated with anaemia (OR: 0.26, 95% CI: 0.12, 0.55). Reasons for inconsistent consumption included not registering to antenatal clinic, not receiving IFA tablets from the health worker and perceived lack of need. At the supply side, an analysis of IFA stock data at various levels of the health care (n = 168) providers from primary to tertiary levels showed that 14 out of 52 villages surveyed did not have access to IFA tablets. The closest availability of an IFA tablet for 16 villages, was more than 5 km away. To improve the uptake of IFA supplementation and thereby reduce iron deficiency anaemia in pregnant women, a constant supply of IFA at the village or sub-centre level, where frontline workers can promote uptake, should be ensured. FAU - Varghese, Jithin Sam AU - Varghese JS AUID- ORCID: 0000-0003-3825-9897 AD - Division of Nutrition, St. John's Research Institute, Bangalore, India. FAU - Swaminathan, Sumathi AU - Swaminathan S AD - Division of Nutrition, St. John's Research Institute, Bangalore, India. FAU - Kurpad, Anura V AU - Kurpad AV AD - Division of Nutrition, St. John's Research Institute, Bangalore, India. AD - Department of Physiology, St. John's Medical College, Bangalore, India. FAU - Thomas, Tinku AU - Thomas T AUID- ORCID: 0000-0002-1786-6076 AD - Department of Biostatistics, St. John's Medical College, Bangalore, India. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20190130 PL - United States TA - PLoS One JT - PloS one JID - 101285081 RN - 935E97BOY8 (Folic Acid) RN - E1UOL152H7 (Iron) SB - IM MH - Adult MH - Anemia, Iron-Deficiency/*epidemiology/*prevention & control MH - Dietary Supplements MH - Female MH - Folic Acid/*therapeutic use MH - Humans MH - India/epidemiology MH - Iron/*therapeutic use MH - Pregnancy MH - Prenatal Care MH - Risk Factors MH - Socioeconomic Factors PMC - PMC6353128 COIS- The authors have declared that no competing interests exist. EDAT- 2019/01/31 06:00 MHDA- 2019/10/19 06:00 PMCR- 2019/01/30 CRDT- 2019/01/31 06:00 PHST- 2018/04/02 00:00 [received] PHST- 2018/12/29 00:00 [accepted] PHST- 2019/01/31 06:00 [entrez] PHST- 2019/01/31 06:00 [pubmed] PHST- 2019/10/19 06:00 [medline] PHST- 2019/01/30 00:00 [pmc-release] AID - PONE-D-18-09827 [pii] AID - 10.1371/journal.pone.0210634 [doi] PST - epublish SO - PLoS One. 2019 Jan 30;14(1):e0210634. doi: 10.1371/journal.pone.0210634. eCollection 2019.