PMID- 30699882
OWN - NLM
STAT- MEDLINE
DCOM- 20190403
LR  - 20190403
IS  - 1573-2517 (Electronic)
IS  - 0165-0327 (Linking)
VI  - 245
DP  - 2019 Feb 15
TI  - Course of a major postpartum depressive episode: A prospective 2 years 
      naturalistic follow-up study.
PG  - 965-970
LID - S0165-0327(18)30152-6 [pii]
LID - 10.1016/j.jad.2018.11.062 [doi]
AB  - BACKGROUND: Survival methodology has not already been used in studies about 
      postpartum depression (PPD) course. The aims of the present study were to 
      estimate the duration of a Major Postpartum Depressive Episode (MPDE) during 2 
      years, as well as to explore factors associated with the course. METHOD: This was 
      a prospective, naturalistic, longitudinal study with a cohort of 165 women with a 
      MPDE (DSM-IV criteria). Potential predictors of prognosis were recorded at 
      baseline. Follow-up was conducted using the Longitudinal Interval Follow-up 
      Evaluation (LIFE). RESULTS: Of the total sample, 110 (66.7%) completed the 2 
      years follow-up. The mean time to full remission was 49.4 weeks (95% CI: 
      44.0-59.8). The probability of recovering was 30.2% (95% CI: 22.1%-37.4%) at 6 
      months of follow-up, 66.3% (95% CI: 57.4%-73.4%) at 12 months of follow-up, and 
      90.3% (95% CI: 79.8%-95.4%) at 24 months of follow-up. Mothers with financial 
      difficulties, onset of depressive episode previous to birth, and those with prior 
      treated depressive episodes took longer in achieving full remission. LIMITATIONS: 
      Results are only generalizable to mothers with PPD treated in a psychiatric 
      outpatient setting. Psychopharmacological treatment was uncontrolled and 
      personality was not assessed. CONCLUSIONS: Our findings suggest that PPD could 
      become a chronic disorder, particularly in mothers with an onset of the episode 
      previous to birth, with a history of depression or with financial problems. 
      Knowledge of these factors may help to improve the guidelines of depression 
      management and treatment during the perinatal period.
CI  - Copyright (c) 2018. Published by Elsevier B.V.
FAU - Torres, Anna
AU  - Torres A
AD  - Unitat de Salut Mental Perinatal CLINIC-BCN, Hospital Clinic, Barcelona, Spain; 
      Institut D'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, 
      Spain; Department of Psychiatry and Clinical Psychology, Universitat de 
      Barcelona, Barcelona, Spain.
FAU - Gelabert, Estel
AU  - Gelabert E
AD  - Department of Clinical and Health Psychology, Universitat Autonoma de Barcelona, 
      Bellaterra, Spain.
FAU - Roca, Alba
AU  - Roca A
AD  - Unitat de Salut Mental Perinatal CLINIC-BCN, Hospital Clinic, Barcelona, Spain.
FAU - Navarro, Purificacion
AU  - Navarro P
AD  - Servei de Psicologia, Regidoria de Politiques de Genere Ajuntament de Terrassa, 
      Terrassa, Spain.
FAU - Plaza, Anna
AU  - Plaza A
AD  - Unitat de Crisi i Prevencio del Suicidi, CPB-Dreta Eixample, Barcelona, Spain.
FAU - Subira, Susana
AU  - Subira S
AD  - Department of Clinical and Health Psychology, Universitat Autonoma de Barcelona, 
      Bellaterra, Spain.
FAU - Martin-Santos, Rocio
AU  - Martin-Santos R
AD  - Institut D'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, 
      Spain; Department of Psychiatry and Clinical Psychology, Hospital Clinic, 
      Barcelona, Spain; Department of Medicine, Universitat de Barcelona, Barcelona, 
      Spain; Centro de Investigacion Biomedica en Red de Salud Mental (CIBERSAM), 
      Spain.
FAU - Ascaso, Carlos
AU  - Ascaso C
AD  - Institut D'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, 
      Spain; Biostatistics Unit, Public Health Department, Universitat de Barcelona, 
      Barcelona, Spain.
FAU - Garcia-Esteve, Lluisa
AU  - Garcia-Esteve L
AD  - Unitat de Salut Mental Perinatal CLINIC-BCN, Hospital Clinic, Barcelona, Spain; 
      Institut D'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, 
      Spain. Electronic address: LESTEVE@clinic.cat.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20181105
PL  - Netherlands
TA  - J Affect Disord
JT  - Journal of affective disorders
JID - 7906073
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Chronic Disease
MH  - Cohort Studies
MH  - Depression, Postpartum/*psychology
MH  - Depressive Disorder, Major/*psychology
MH  - Diagnostic and Statistical Manual of Mental Disorders
MH  - Disease Progression
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Longitudinal Studies
MH  - Mothers
MH  - Personality
MH  - Pregnancy
MH  - Pregnancy Complications/*psychology
MH  - Prognosis
MH  - Prospective Studies
MH  - Socioeconomic Factors
MH  - Young Adult
OTO - NOTNLM
OT  - Course
OT  - Longitudinal study
OT  - Postpartum depression
OT  - Risk factors
EDAT- 2019/02/01 06:00
MHDA- 2019/04/04 06:00
CRDT- 2019/02/01 06:00
PHST- 2018/01/22 00:00 [received]
PHST- 2018/09/30 00:00 [revised]
PHST- 2018/11/03 00:00 [accepted]
PHST- 2019/02/01 06:00 [entrez]
PHST- 2019/02/01 06:00 [pubmed]
PHST- 2019/04/04 06:00 [medline]
AID - S0165-0327(18)30152-6 [pii]
AID - 10.1016/j.jad.2018.11.062 [doi]
PST - ppublish
SO  - J Affect Disord. 2019 Feb 15;245:965-970. doi: 10.1016/j.jad.2018.11.062. Epub 
      2018 Nov 5.