PMID- 30703074
OWN - NLM
STAT- MEDLINE
DCOM- 20190410
LR  - 20200225
IS  - 1643-3750 (Electronic)
IS  - 1234-1010 (Print)
IS  - 1234-1010 (Linking)
VI  - 25
DP  - 2019 Jan 31
TI  - Correlation Between Smoking and Passive Smoking with Multiple Sclerosis and the 
      Underlying Molecular Mechanisms.
PG  - 893-902
LID - 10.12659/MSM.912863 [doi]
AB  - Multiple sclerosis (MS) is a chronic immune-mediated disease of the spinal cord 
      and brain. Many studies have shown that smoking and passive smoking are key 
      environmental risk factors for MS. Here, we provide an overview of the human 
      leukocyte antigen (HLA) gene studies on smoking and MS risk, and we discuss 
      recent studies on between epigenetics and smoking-induced MS. In addition, in 
      this review we also summarize current research advances in biological pathways 
      and smoking-induced MS. This review provides an overview of studies on the 
      association between smoking, passive smoking, and MS susceptibility, and the 
      underlying molecular mechanism.
FAU - Wang, Zhaowei
AU  - Wang Z
AD  - Department of Neurology, Shaoxing People's Hospital (Shaoxing Hospital of 
      Zhejiang University), Shaoxing, Zhejiang, China (mainland).
FAU - Xie, Jianpin
AU  - Xie J
AD  - Department of Neurology, Shaoxing People's Hospital (Shaoxing Hospital of 
      Zhejiang University), Shaoxing, Zhejiang, China (mainland).
FAU - Wu, Chenglong
AU  - Wu C
AD  - Department of Neurology, Shaoxing People's Hospital (Shaoxing Hospital of 
      Zhejiang University), Shaoxing, Zhejiang, China (mainland).
FAU - Xiao, Guirong
AU  - Xiao G
AD  - Department of Neurology, Shaoxing People's Hospital (Shaoxing Hospital of 
      Zhejiang University), Shaoxing, Zhejiang, China (mainland).
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20190131
PL  - United States
TA  - Med Sci Monit
JT  - Medical science monitor : international medical journal of experimental and 
      clinical research
JID - 9609063
RN  - 0 (HLA Antigens)
RN  - 0 (Tobacco Smoke Pollution)
SB  - IM
MH  - China
MH  - Cigarette Smoking/*adverse effects
MH  - Epigenesis, Genetic/genetics
MH  - Genetic Predisposition to Disease/genetics
MH  - HLA Antigens/genetics
MH  - Humans
MH  - Multiple Sclerosis/*etiology/metabolism/physiopathology
MH  - Risk Factors
MH  - Smoking/adverse effects
MH  - Tobacco Smoke Pollution/*adverse effects
PMC - PMC6367889
COIS- Conflict of interests None.
EDAT- 2019/02/01 06:00
MHDA- 2019/04/11 06:00
PMCR- 2019/01/31
CRDT- 2019/02/01 06:00
PHST- 2019/02/01 06:00 [entrez]
PHST- 2019/02/01 06:00 [pubmed]
PHST- 2019/04/11 06:00 [medline]
PHST- 2019/01/31 00:00 [pmc-release]
AID - 912863 [pii]
AID - 10.12659/MSM.912863 [doi]
PST - epublish
SO  - Med Sci Monit. 2019 Jan 31;25:893-902. doi: 10.12659/MSM.912863.