PMID- 30704638 OWN - NLM STAT- MEDLINE DCOM- 20190314 LR - 20190314 IS - 1558-3147 (Electronic) IS - 0193-953X (Linking) VI - 42 IP - 1 DP - 2019 Mar TI - Binge-Eating Disorder. PG - 33-43 LID - S0193-953X(18)31169-9 [pii] LID - 10.1016/j.psc.2018.10.011 [doi] AB - Binge-eating disorder (BED), first included as a diagnostic entity in the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition, is characterized by recurrent episodes of binge eating without regular compensatory behaviors to prevent weight gain. With a complex multifactorial etiology, BED is the most frequent eating disorder co-occuring with significant psychopathology, mental and physical comorbidity, obesity, and life impairment. Despite its significance, BED is not sufficiently diagnosed or treated. Evidence-based treatments for BED include psychotherapy and structured self-help treatment, with cognitive-behavioral therapy as most well-established approach, and pharmacotherapy with lisdexamfetamine as FDA approved medication with a limitation of use. CI - Copyright (c) 2018 Elsevier Inc. All rights reserved. FAU - Hilbert, Anja AU - Hilbert A AD - Integrated Research and Treatment Center AdiposityDiseases, Department of Medical Psychology and Medical Sociology, Department of Psychosomatic Medicine and Psychotherapy, University of Leipzig Medical Center, Philipp-Rosenthal-Strasse 27, Leipzig 04103, Germany. Electronic address: anja.hilbert@medizin.uni-leipzig.de. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review DEP - 20181222 PL - United States TA - Psychiatr Clin North Am JT - The Psychiatric clinics of North America JID - 7708110 RN - 0 (Antidepressive Agents, Second-Generation) RN - 0 (Central Nervous System Stimulants) SB - IM MH - Antidepressive Agents, Second-Generation/*therapeutic use MH - Binge-Eating Disorder/*diagnosis/drug therapy/etiology/*therapy MH - Central Nervous System Stimulants/*therapeutic use MH - Humans MH - Psychotherapy/*methods MH - *Weight Loss OTO - NOTNLM OT - Binge eating OT - Diagnosis OT - Eating disorder OT - Obesity OT - Treatment EDAT- 2019/02/02 06:00 MHDA- 2019/03/15 06:00 CRDT- 2019/02/02 06:00 PHST- 2019/02/02 06:00 [entrez] PHST- 2019/02/02 06:00 [pubmed] PHST- 2019/03/15 06:00 [medline] AID - S0193-953X(18)31169-9 [pii] AID - 10.1016/j.psc.2018.10.011 [doi] PST - ppublish SO - Psychiatr Clin North Am. 2019 Mar;42(1):33-43. doi: 10.1016/j.psc.2018.10.011. Epub 2018 Dec 22.