PMID- 30716814
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 2096-7993 (Print)
IS  - 2096-7993 (Linking)
VI  - 32
IP  - 22
DP  - 2018 Nov
TI  - [Treg influences the pathogenesis of allergic rhinitis through TICAM-1 pathway].
PG  - 1763-1766
LID - 10.13201/j.issn.1001-1781.2018.22.020 [doi]
AB  - Allergic rhinitis is an immunoglobulin E (IgE)-mediated type I allergic disorder 
      of the nasal mucosa, which is caused by an imbalance in the cytokine network, a 
      number of intracellular signaling pathways being actived. Treg is known to have 
      immunosuppressive effects. Numerous studies have shown that Toll-like receptors 
      play an important immunomodulatory role in the pathogenesis of allergic rhinitis, 
      and TICAM-1, as an important adaptor protein in the Toll-like receptor domain, is 
      involved in signal transduction of allergic rhinitis. This article reviews Treg's 
      impact on the pathogenesis of allergic rhinitis through the TICAM-1 pathway to 
      further understand the role of allergic rhinitis in the pathogenesis and to 
      provide new ideas for therapeutic goals for allergic rhinitis.
CI  - Copyright(c) by the Editorial Department of Journal of Clinical Otorhinolaryngology 
      Head and Neck Surgery.
FAU - Zhang, L X
AU  - Zhang LX
FAU - Liu, T
AU  - Liu T
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Review
PL  - China
TA  - Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
JT  - Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical 
      otorhinolaryngology, head, and neck surgery
JID - 101303164
OTO - NOTNLM
OT  - rhinitis, allergic
OT  - TICAM-1
OT  - Treg
COIS- The authors of this article and the planning committee members and staff have no 
      relevant financial relationships with commercial interests to disclose.
EDAT- 2019/02/06 06:00
MHDA- 2019/02/06 06:01
CRDT- 2019/02/06 06:00
PHST- 2018/06/05 00:00 [received]
PHST- 2019/02/06 06:00 [entrez]
PHST- 2019/02/06 06:00 [pubmed]
PHST- 2019/02/06 06:01 [medline]
AID - 10.13201/j.issn.1001-1781.2018.22.020 [doi]
PST - ppublish
SO  - Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Nov;32(22):1763-1766. doi: 
      10.13201/j.issn.1001-1781.2018.22.020.