PMID- 30721433
OWN - NLM
STAT- MEDLINE
DCOM- 20190419
LR  - 20200225
IS  - 1614-7499 (Electronic)
IS  - 0944-1344 (Linking)
VI  - 26
IP  - 7
DP  - 2019 Mar
TI  - Web-based Korean maximum residue limit evaluation tools: an applied example of 
      maximum residue limit evaluation for trichlorfon in fishery products.
PG  - 7284-7299
LID - 10.1007/s11356-019-04314-y [doi]
AB  - To ensure public safety against veterinary drug residues in food products from 
      animal sources, maximum residue limits (MRLs) should be established by scientific 
      evidence and a transparent estimation process. The Joint Food and Agriculture 
      Organization (FAO)/World Health Organization (WHO) Expert Committee on Food 
      Additives (JECFA) developed an Excel workbook-based tool for MRLs evaluation in 
      2003. In this study, we developed a web-based tool for MRL evaluation, called 
      Korean MRL evaluation tools (KMET). While KMET used algorithms of JECFA workbook, 
      it added some databases (e.g., Korean food consumption database) and provided 
      additional functions (e.g., selection of target marker residue). Web-based KMET 
      enabled regulatory policy makers to update the database. All input data and 
      output results related to MRL evaluation based on residue depletion and food 
      consumption datasets were archived and provided overall processes from the 
      initial depletion data entry to MRL establishment with user-friendly interface. 
      Our results demonstrated the stepwise processes whereby MRL for trichlorfon in 
      the muscle of Paralichthys olivaceus was established with functional descriptions 
      of KMET. MRL for trichlorfon derived from KMET was proposed and notified by the 
      Ministry of Food and Drug Safety in 2018.
FAU - Kang, Hui-Seung
AU  - Kang HS
AD  - Pesticide and Veterinary Drugs Residue Division, National Institute of Food and 
      Drug Safety Evaluation, Osong, Cheongju, Chungcheongbuk-do, 361-709, Republic of 
      Korea.
FAU - Kwon, Nam Ji
AU  - Kwon NJ
AD  - CHEM.I.NET Ltd., Room 302, 773-3, Mok-dong, Yangcheon-gu, Seoul, South Korea.
FAU - Jeong, Jiyoon
AU  - Jeong J
AD  - Pesticide and Veterinary Drugs Residue Division, National Institute of Food and 
      Drug Safety Evaluation, Osong, Cheongju, Chungcheongbuk-do, 361-709, Republic of 
      Korea.
FAU - Lee, Kiyoung
AU  - Lee K
AD  - Department of Environmental Health, Graduate School of Public Health, Seoul 
      National University, Seoul, 08826, South Korea.
FAU - Lee, Hunjoo
AU  - Lee H
AD  - CHEM.I.NET Ltd., Room 302, 773-3, Mok-dong, Yangcheon-gu, Seoul, South Korea. 
      adstar@cheminet.kr.
LA  - eng
GR  - 16162MFDS588/Ministry of food and drug safety/
GR  - 17161MFDS651/Ministry of food and drug safety/
PT  - Journal Article
DEP - 20190205
PL  - Germany
TA  - Environ Sci Pollut Res Int
JT  - Environmental science and pollution research international
JID - 9441769
RN  - 0 (Food Additives)
RN  - 0 (Pesticide Residues)
RN  - 0 (Veterinary Drugs)
RN  - DBF2DG4G2K (Trichlorfon)
SB  - IM
MH  - Agriculture
MH  - Animals
MH  - Drug Residues/*analysis/standards
MH  - Environmental Policy/*legislation & jurisprudence
MH  - Fisheries/statistics & numerical data
MH  - Food
MH  - Food Additives
MH  - Food Contamination/legislation & jurisprudence/statistics & numerical data
MH  - Food Supply
MH  - Humans
MH  - Internet
MH  - Pesticide Residues
MH  - Republic of Korea
MH  - Trichlorfon/*analysis/standards
MH  - Veterinary Drugs/*analysis/standards
MH  - World Health Organization
OTO - NOTNLM
OT  - Exposure assessment
OT  - Maximum residue limits
OT  - Residue depletion
OT  - Trichlorfon
OT  - Web-based tool
EDAT- 2019/02/06 06:00
MHDA- 2019/04/20 06:00
CRDT- 2019/02/06 06:00
PHST- 2018/10/02 00:00 [received]
PHST- 2019/01/22 00:00 [accepted]
PHST- 2019/02/06 06:00 [pubmed]
PHST- 2019/04/20 06:00 [medline]
PHST- 2019/02/06 06:00 [entrez]
AID - 10.1007/s11356-019-04314-y [pii]
AID - 10.1007/s11356-019-04314-y [doi]
PST - ppublish
SO  - Environ Sci Pollut Res Int. 2019 Mar;26(7):7284-7299. doi: 
      10.1007/s11356-019-04314-y. Epub 2019 Feb 5.