PMID- 30734684
OWN - NLM
STAT- MEDLINE
DCOM- 20200102
LR  - 20200102
IS  - 1876-1038 (Electronic)
IS  - 1574-8871 (Linking)
VI  - 14
IP  - 2
DP  - 2019
TI  - Mitral Stenosis in Pregnancy: A Comprehensive Review of a Challenging 
      Cardio-Obstetric Clinical Entity.
PG  - 136-140
LID - 10.2174/1574887114666190207154413 [doi]
AB  - BACKGROUND: Mitral stenosis is one of the most commonly encountered valvular 
      heart diseases during pregnancy, the majority are rheumatic in origin and poorly 
      tolerated due to cardiocirculatory changes that occur during pregnancy, labor and 
      postpartum. OBJECTIVE: The distinctive physiological events that arise during 
      pregnancy and labor and the influence of mitral stenosis are tackled in this 
      article. METHODS: Through PUBMED and MEDLINE searches, we reviewed the literature 
      of the last decade as well as the recommendations from guidelines of high-impact 
      worldwide. RESULTS: Cardiac decompensation usually takes place late in pregnancy 
      as the hemodynamic burden of pregnancy become more pronounced as well as after 
      delivery due to an abrupt increase of preload secondary to autotransfusion and 
      aorto-caval decompression. The maternal and fetal complications correlate with 
      the New York Heart Association (NYHA) functional classification and the grade of 
      mitral stenosis. Medical therapy should be tried first. If symptoms continue in 
      spite of optimal medical therapy, invasive procedures are recommended. Several 
      studies revealed that vaginal delivery under epidural anesthesia is endurable and 
      of low-risk unless obstetrically contraindicated. CONCLUSION: Pregnancy and 
      mitral stenosis remain a complex entity and a well-known trigger of maternal 
      mortality during pregnancy and peri-partum period if not managed adequately. A 
      good appreciation and recognition of the physiology of pregnancy and its impact 
      on the pre-existing mitral stenosis and the presence of a specialized 
      multidisciplinary team to handle such cases significantly decrease maternal and 
      fetal mortality and morbidity.
CI  - Copyright(c) Bentham Science Publishers; For any queries, please email at 
      epub@benthamscience.net.
FAU - Abdelrahman, Safinaz
AU  - Abdelrahman S
AD  - Department of Obstetrics and Gynecology, Salmaniya Medical Complex, Manama, 
      Bahrain.
FAU - Yousif, Nooraldaem
AU  - Yousif N
AD  - Department of Cardiology, University Heart Center at University Hospital Zurich, 
      Zurich, Switzerland.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United Arab Emirates
TA  - Rev Recent Clin Trials
JT  - Reviews on recent clinical trials
JID - 101270873
SB  - IM
MH  - Female
MH  - Humans
MH  - Mitral Valve Stenosis/diagnosis/*therapy
MH  - Pregnancy
MH  - Pregnancy Complications/diagnosis/*therapy
OTO - NOTNLM
OT  - Cardiac decompensation
OT  - cardio-obstetric clinical entity
OT  - mitral stenosis
OT  - postpartum
OT  - pregnancy
OT  - valvular heart diseases.
EDAT- 2019/02/09 06:00
MHDA- 2020/01/03 06:00
CRDT- 2019/02/09 06:00
PHST- 2018/09/26 00:00 [received]
PHST- 2019/01/19 00:00 [revised]
PHST- 2019/01/25 00:00 [accepted]
PHST- 2019/02/09 06:00 [pubmed]
PHST- 2020/01/03 06:00 [medline]
PHST- 2019/02/09 06:00 [entrez]
AID - RRCT-EPUB-96491 [pii]
AID - 10.2174/1574887114666190207154413 [doi]
PST - ppublish
SO  - Rev Recent Clin Trials. 2019;14(2):136-140. doi: 
      10.2174/1574887114666190207154413.