PMID- 30738613
OWN - NLM
STAT- MEDLINE
DCOM- 20190603
LR  - 20190603
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1593
DP  - 2019 May 24
TI  - Simultaneous determination of 58 pesticides and relevant metabolites in eggs with 
      a multi-functional filter by ultra-high performance liquid chromatography-tandem 
      mass spectrometry.
PG  - 81-90
LID - S0021-9673(19)30126-8 [pii]
LID - 10.1016/j.chroma.2019.01.074 [doi]
AB  - A sensitive method for the simultaneous determination of 58 pesticides and 
      relevant metabolites in eggs was developed using ultra-high performance liquid 
      chromatography-tandem mass spectrometry (UHPLC-MS/MS) after clean-up with a 
      multi-functional filter (MFF) based on quick, easy, cheap, effective, rugged, and 
      safe method (QuEChERS). The egg sample was extracted with 5 ml water and 10 ml 1% 
      acetic acid in acetonitrile and then salt out with sodium chloride. The extracted 
      solution was filtered directly through an MFF containing 50 mg PSA, 50 mg C18, 
      and 150 mg magnesium sulphate before UHPLC-MS/MS analysis. The clean-up and 
      filter procedures were integrated using the MFF to substantially improve the work 
      efficiency. Good linearity was shown for each analyte, and all the correlation 
      coefficients exceeded 0.99. The recoveries in the eggs at the five spiked levels 
      were 74.4%-115.2%, and the relative standard deviations (RSDs) were less than 
      15.3%. The limit of detection (LOD) and the limit of quantitation (LOQ) of 58 
      pesticides and 8 metabolites in eggs were 0.1-1.0 mug/kg and 0.2-5.0 mug/kg, 
      respectively. The decision limit (CCalpha) and detection capacity (CCbeta) were 
      3.4-111.1 mug/kg and 6.8-122.1 mug/kg, respectively. This method has also been 
      successfully applied in the determination of actual eggs samples. This developed 
      method is more effective and faster in the monitoring of pesticide residue in 
      eggs compared to the traditional analytical method.
CI  - Copyright (c) 2019 Elsevier B.V. All rights reserved.
FAU - Zhang, Xining
AU  - Zhang X
AD  - Institute of Quality Standards and Testing Technology for Agro-Products, Key 
      Laboratory of Agro-product Quality and Safety, Chinese Academy of Agricultural 
      Sciences, Beijing, 100081, China; Key Laboratory of Agri-food Quality and Safety, 
      Ministry of Agriculture, Beijing, 100081, China.
FAU - Song, Yue
AU  - Song Y
AD  - Institute of Quality Standards and Testing Technology for Agro-Products, Key 
      Laboratory of Agro-product Quality and Safety, Chinese Academy of Agricultural 
      Sciences, Beijing, 100081, China; Key Laboratory of Agri-food Quality and Safety, 
      Ministry of Agriculture, Beijing, 100081, China.
FAU - Jia, Qi
AU  - Jia Q
AD  - Institute of Quality Standards and Testing Technology for Agro-Products, Key 
      Laboratory of Agro-product Quality and Safety, Chinese Academy of Agricultural 
      Sciences, Beijing, 100081, China; Key Laboratory of Agri-food Quality and Safety, 
      Ministry of Agriculture, Beijing, 100081, China.
FAU - Zhang, Lin
AU  - Zhang L
AD  - Institute of Quality Standards and Testing Technology for Agro-Products, Key 
      Laboratory of Agro-product Quality and Safety, Chinese Academy of Agricultural 
      Sciences, Beijing, 100081, China; Key Laboratory of Agri-food Quality and Safety, 
      Ministry of Agriculture, Beijing, 100081, China.
FAU - Zhang, Wei
AU  - Zhang W
AD  - Institute of Quality Standards and Testing Technology for Agro-Products, Key 
      Laboratory of Agro-product Quality and Safety, Chinese Academy of Agricultural 
      Sciences, Beijing, 100081, China; Key Laboratory of Agri-food Quality and Safety, 
      Ministry of Agriculture, Beijing, 100081, China.
FAU - Mu, Pengqian
AU  - Mu P
AD  - China Asia Pacific Application Support Center, AB SCIEX, Shanghai, 200050, China.
FAU - Jia, Yanbo
AU  - Jia Y
AD  - China Asia Pacific Application Support Center, AB SCIEX, Shanghai, 200050, China.
FAU - Qian, Yongzhong
AU  - Qian Y
AD  - Institute of Quality Standards and Testing Technology for Agro-Products, Key 
      Laboratory of Agro-product Quality and Safety, Chinese Academy of Agricultural 
      Sciences, Beijing, 100081, China; Key Laboratory of Agri-food Quality and Safety, 
      Ministry of Agriculture, Beijing, 100081, China.
FAU - Qiu, Jing
AU  - Qiu J
AD  - Institute of Quality Standards and Testing Technology for Agro-Products, Key 
      Laboratory of Agro-product Quality and Safety, Chinese Academy of Agricultural 
      Sciences, Beijing, 100081, China; Key Laboratory of Agri-food Quality and Safety, 
      Ministry of Agriculture, Beijing, 100081, China. Electronic address: 
      qiujing@caas.cn.
LA  - eng
PT  - Journal Article
DEP - 20190129
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Pesticide Residues)
SB  - IM
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Eggs/*analysis
MH  - Limit of Detection
MH  - Pesticide Residues/*analysis
MH  - Reproducibility of Results
MH  - Tandem Mass Spectrometry/*methods
OTO - NOTNLM
OT  - Eggs
OT  - Multi-functional filter
OT  - Pesticides
OT  - QuEChERS
OT  - UHPLC-MS/MS
EDAT- 2019/02/11 06:00
MHDA- 2019/06/04 06:00
CRDT- 2019/02/11 06:00
PHST- 2018/08/06 00:00 [received]
PHST- 2019/01/17 00:00 [revised]
PHST- 2019/01/28 00:00 [accepted]
PHST- 2019/02/11 06:00 [pubmed]
PHST- 2019/06/04 06:00 [medline]
PHST- 2019/02/11 06:00 [entrez]
AID - S0021-9673(19)30126-8 [pii]
AID - 10.1016/j.chroma.2019.01.074 [doi]
PST - ppublish
SO  - J Chromatogr A. 2019 May 24;1593:81-90. doi: 10.1016/j.chroma.2019.01.074. Epub 
      2019 Jan 29.