PMID- 30743169 OWN - NLM STAT- MEDLINE DCOM- 20190429 LR - 20190429 IS - 1090-2414 (Electronic) IS - 0147-6513 (Linking) VI - 172 DP - 2019 May 15 TI - Application and enantioselective residue determination of chiral pesticide penconazole in grape, tea, aquatic vegetables and soil by ultra performance liquid chromatography-tandem mass spectrometry. PG - 530-537 LID - S0147-6513(19)30130-7 [pii] LID - 10.1016/j.ecoenv.2019.01.103 [doi] AB - Penconazole is a typical triazole fungicide with wide use on fruits, vegetables, and tea plants to control powdery mildew. In the present study, an efficient graphite carbon black solid phase extraction (GCB-SPE) purification combined with chiral ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method was developed for determination of penconazole enantiomers in different complex matrices, including grape, tea, soil, lotus root, lotus leaf, lotus seed and hulls. The method was then applied to investigate the enantioselective dissipation of penconazole enantiomers in a real field experiment of grape and soil. As a result, a satisfactory separation of penconazole enantiomers on a chiral Lux Cellulose-2 column (150 mm x 2 mm i.d., 3 microm) was obtained with 0.1% formic acid in methanol and 10 mmol L(-1) ammonium acetate in water (75/25, v/v) as mobile phase at 0.25 mL min(-1). The enantiomer (+)-penconazole was firstly eluted, and (-)-penconazole was then eluted. The method showed reliable performances in linearity, recovery and precision, the recoveries of (+)-penconazole and (-)-penconazole in all of six matrices were between 70.5% and 121.0% with the relative standard deviations (RSDs) ranging from 0.8% to 23.6% at the low, medium and high spiked levels. The limits of quantitation (LOQs) of this method were lower than 0.0025 mg kg(-1) in grape, soil and lotus root, 0.005 mg kg(-1) in lotus leaf, lotus seed meat and lotus seed shell, and 0.0125 mg kg(-1) in tea. Results of field trials indicated that (-)-penconazole degraded faster than its (+)-isomer in grape. While only a moderate stereoselectivity was observed in soil, with (-)-penconazole preferential degraded. The proposed method could be used to investigate enantioselective environmental behavior of penconazole enantiomers in complex matrices. And results in this study could provide useful information on realistic risk assessment of penconazole in grape. CI - Copyright (c) 2019 Elsevier Inc. All rights reserved. FAU - Zhang, Xinzhong AU - Zhang X AD - Research Center of Quality Safety for Agricultural Products, Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China; Key Laboratory of Tea Quality and Safety Control, Ministry of Agriculture, Hangzhou 310008, China. Electronic address: zhangxinzhong@tricaas.com. FAU - Wang, Xinru AU - Wang X AD - Research Center of Quality Safety for Agricultural Products, Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China. Electronic address: wangxinru@tricaas.com. FAU - Luo, Fengjian AU - Luo F AD - Research Center of Quality Safety for Agricultural Products, Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China; Key Laboratory of Tea Quality and Safety Control, Ministry of Agriculture, Hangzhou 310008, China. Electronic address: lfj@tricaas.com. FAU - Sheng, Huishan AU - Sheng H AD - Research Center of Quality Safety for Agricultural Products, Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China; College of Horticulture and Landscape, Tianjin Agricultural University, Tianjin 300384, China. Electronic address: 18202248794@163.com. FAU - Zhou, Li AU - Zhou L AD - Research Center of Quality Safety for Agricultural Products, Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China; Key Laboratory of Tea Quality and Safety Control, Ministry of Agriculture, Hangzhou 310008, China. Electronic address: lizhou@tricaas.com. FAU - Zhong, Qing AU - Zhong Q AD - Research Center of Quality Safety for Agricultural Products, Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China. Electronic address: tsingchung@qq.com. FAU - Lou, Zhengyun AU - Lou Z AD - Research Center of Quality Safety for Agricultural Products, Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China; Key Laboratory of Tea Quality and Safety Control, Ministry of Agriculture, Hangzhou 310008, China. Electronic address: louzy@tricaas.com. FAU - Sun, Hezhi AU - Sun H AD - Research Center of Quality Safety for Agricultural Products, Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China. Electronic address: sunhezhi@tricaas.com. FAU - Yang, Mei AU - Yang M AD - Research Center of Quality Safety for Agricultural Products, Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China. Electronic address: ymei2016@126.com. FAU - Cui, Xuan AU - Cui X AD - Research Center of Quality Safety for Agricultural Products, Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China; College of Horticulture and Landscape, Tianjin Agricultural University, Tianjin 300384, China. Electronic address: 624116422@qq.com. FAU - Chen, Zongmao AU - Chen Z AD - Research Center of Quality Safety for Agricultural Products, Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China; Key Laboratory of Tea Quality and Safety Control, Ministry of Agriculture, Hangzhou 310008, China. Electronic address: zmchen2006@163.com. LA - eng PT - Journal Article DEP - 20190208 PL - Netherlands TA - Ecotoxicol Environ Saf JT - Ecotoxicology and environmental safety JID - 7805381 RN - 0 (Pesticide Residues) RN - 0 (Pesticides) RN - 0 (Soil) RN - 0 (Soil Pollutants) RN - 0 (Tea) RN - 0 (Triazoles) RN - 3UN9F9ZJ43 (penconazole) SB - IM MH - Chromatography, High Pressure Liquid MH - Fruit/chemistry MH - Pesticide Residues/analysis MH - Pesticides/*analysis MH - Soil/*chemistry MH - Soil Pollutants/analysis MH - Solid Phase Extraction MH - Stereoisomerism MH - Tandem Mass Spectrometry MH - Tea/*chemistry MH - Triazoles/*analysis MH - Vegetables/*chemistry MH - Vitis/*chemistry OTO - NOTNLM OT - Enantioselective residue determination OT - Grape OT - Lotus OT - Penconazole OT - Tea OT - Ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) EDAT- 2019/02/12 06:00 MHDA- 2019/04/30 06:00 CRDT- 2019/02/12 06:00 PHST- 2018/12/03 00:00 [received] PHST- 2019/01/18 00:00 [revised] PHST- 2019/01/29 00:00 [accepted] PHST- 2019/02/12 06:00 [pubmed] PHST- 2019/04/30 06:00 [medline] PHST- 2019/02/12 06:00 [entrez] AID - S0147-6513(19)30130-7 [pii] AID - 10.1016/j.ecoenv.2019.01.103 [doi] PST - ppublish SO - Ecotoxicol Environ Saf. 2019 May 15;172:530-537. doi: 10.1016/j.ecoenv.2019.01.103. Epub 2019 Feb 8.