PMID- 30746133
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 2048-8505 (Print)
IS  - 2048-8513 (Electronic)
IS  - 2048-8505 (Linking)
VI  - 12
IP  - 1
DP  - 2019 Feb
TI  - Azathioprine hypersensitivity syndrome in anti-myeloperoxidase anti-neutrophil 
      cytoplasmic antibody-associated vasculitis.
PG  - 89-91
LID - 10.1093/ckj/sfy038 [doi]
AB  - Two patients with anti-neutrophil cytoplasmic antibody-associated vasculitis 
      (AAV) and rapid onset of high fever, tachycardia and systemic hypotension 
      accompanied by elevated laboratory markers of infection were diagnosed with 
      azathioprine hypersensitivity syndrome only after repeat exposure. Azathioprine 
      hypersensitivity can closely mimic sepsis and/or vasculitis activity and should 
      be considered in AAV, a condition with frequent use of this drug. We discuss the 
      pitfalls in diagnosis and the possible pathophysiologic background.
FAU - Greite, Robert
AU  - Greite R
AD  - Department of Internal Medicine, Division of Nephrology and Hypertension, 
      Hannover Medical School, Hannover, Germany.
FAU - Deutsch, Konstantin
AU  - Deutsch K
AD  - Department of Internal Medicine, Division of Nephrology and Hypertension, 
      Hannover Medical School, Hannover, Germany.
FAU - Brasen, Jan Hinrich
AU  - Brasen JH
AD  - Institute for Pathology, Hannover Medical School, Hannover, Germany.
FAU - von Vietinghoff, Sibylle
AU  - von Vietinghoff S
AD  - Department of Internal Medicine, Division of Nephrology and Hypertension, 
      Hannover Medical School, Hannover, Germany.
LA  - eng
PT  - Journal Article
DEP - 20180523
PL  - England
TA  - Clin Kidney J
JT  - Clinical kidney journal
JID - 101579321
EIN - Clin Kidney J. 2018 Oct 15;12(2):311. PMID: 30976415
PMC - PMC6366126
OTO - NOTNLM
OT  - ANCA vasculitis
OT  - azathioprine
OT  - fever
OT  - relapse
OT  - sepsis
EDAT- 2019/02/13 06:00
MHDA- 2019/02/13 06:01
PMCR- 2018/05/23
CRDT- 2019/02/13 06:00
PHST- 2018/02/07 00:00 [received]
PHST- 2018/04/02 00:00 [accepted]
PHST- 2019/02/13 06:00 [entrez]
PHST- 2019/02/13 06:00 [pubmed]
PHST- 2019/02/13 06:01 [medline]
PHST- 2018/05/23 00:00 [pmc-release]
AID - sfy038 [pii]
AID - 10.1093/ckj/sfy038 [doi]
PST - ppublish
SO  - Clin Kidney J. 2019 Feb;12(1):89-91. doi: 10.1093/ckj/sfy038. Epub 2018 May 23.