PMID- 30760299
OWN - NLM
STAT- MEDLINE
DCOM- 20190705
LR  - 20200225
IS  - 1745-6215 (Electronic)
IS  - 1745-6215 (Linking)
VI  - 20
IP  - 1
DP  - 2019 Feb 13
TI  - Binge-eating disorder treatment goes online - feasibility, usability, and 
      treatment outcome of an Internet-based treatment for binge-eating disorder: study 
      protocol for a three-arm randomized controlled trial including an immediate 
      treatment, a waitlist, and a placebo control group.
PG  - 128
LID - 10.1186/s13063-019-3192-z [doi]
LID - 128
AB  - BACKGROUND: Binge-eating disorder (BED) is characterized by recurrent episodes of 
      loss of control over eating and is related to a higher prevalence of other mental 
      disorders and somatic consequences associated with overweight and obesity. In 
      community-based samples, 2-4% of women and 1-3% men are diagnosed with BED. 
      Psychotherapeutic interventions focusing on maintenance factors of disturbed 
      eating behavior have proven to be effective. However, treatment access is limited 
      for a considerable number of patients with BED. A lack of specialized 
      institutions and treatment resources, but also long distances to treatment 
      facilities for people living in remote or rural areas are often causes of 
      insufficient care. Internet-based guided self-help (GSH) programs have the 
      potential to fill this gap. METHODS: This project aims to develop and evaluate an 
      Internet-based treatment for BED derived from an evidence-based manualized 
      cognitive behavioral therapy (CBT). The primary goal is to test feasibility and 
      suitability of the Internet-based program and to evaluate the treatment outcome 
      in comparison to a pure and a placebo-inspired waitlist control group (i.e. 
      reduction of binge-eating episodes and eating disorder pathology as primary 
      outcome variables). In total, 60 women and men aged 18-70 years with a BED 
      diagnosis will be recruited. The Internet-based GSH treatment comprises eight 
      sessions followed by three booster sessions. The placebo-inspired waitlist 
      control group receives weekly messages containing information increasing positive 
      expectations regarding the treatment effects during the four-week waiting period. 
      The pure waitlist control group receives weekly messages simply asking patients 
      to fill in a short questionnaire. DISCUSSION: The access to evidence-based 
      treatments for BED might be made easier using an Internet-based GSH approach. The 
      present study protocol presents a randomized controlled trial. As well as 
      evaluating the suitability and efficacy of the Internet-based GSH treatment, 
      there will also be a prelimarily investigation on the influence of positive 
      expectations (placebo) for a therapeutic intervention on core symptoms. TRIAL 
      REGISTRATION: German Clinical Trials Register, DRKS00012355 . Registered on 14 
      September 2017.
FAU - Munsch, Simone
AU  - Munsch S
AD  - Department of Clinical Psychology and Psychotherapy, University of Fribourg, Rue 
      de Faucigny 2, 1700, Fribourg, Switzerland. simone.munsch@unifr.ch.
FAU - Wyssen, Andrea
AU  - Wyssen A
AD  - Department of Clinical Psychology and Psychotherapy, University of Fribourg, Rue 
      de Faucigny 2, 1700, Fribourg, Switzerland.
FAU - Vanhulst, Pierre
AU  - Vanhulst P
AD  - Human-IST Institute, University of Fribourg, Boulevard de Perolles 90, 1700, 
      Fribourg, Switzerland.
FAU - Lalanne, Denis
AU  - Lalanne D
AD  - Human-IST Institute, University of Fribourg, Boulevard de Perolles 90, 1700, 
      Fribourg, Switzerland.
FAU - Steinemann, Sharon T
AU  - Steinemann ST
AD  - Department of General Psychology and Methodology, University of Basel, 
      Missionsstrasse 62a, 4055, Basel, Switzerland.
FAU - Tuch, Alexandre
AU  - Tuch A
AD  - Department of General Psychology and Methodology, University of Basel, 
      Missionsstrasse 62a, 4055, Basel, Switzerland.
AD  - Swiss Health Observatory, Federal Statistical Office, Espace de l'Europe 10, 
      2010, Neuchatel, Switzerland.
LA  - eng
GR  - 52-15/Swiss Anorexia Nervosa Foundation/
PT  - Clinical Trial Protocol
PT  - Journal Article
DEP - 20190213
PL  - England
TA  - Trials
JT  - Trials
JID - 101263253
RN  - 0 (Placebos)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Binge-Eating Disorder/*therapy
MH  - *Cognitive Behavioral Therapy
MH  - Control Groups
MH  - Feasibility Studies
MH  - Humans
MH  - *Internet
MH  - Middle Aged
MH  - Placebos
MH  - *Randomized Controlled Trials as Topic
MH  - Treatment Outcome
MH  - Waiting Lists
PMC - PMC6375147
OTO - NOTNLM
OT  - Binge-eating disorder
OT  - Cognitive behavioral therapy
OT  - Guided self-help
OT  - Internet-based treatment
OT  - Placebo
COIS- ETHICS APPROVAL AND CONSENT TO PARTICIPATE: The Ethics Committee of the canton 
      Bern (Switzerland) has evaluated and approved this study. Project-ID: 2017-00102. 
      Date of approval: 27.07.2017. CONSENT FOR PUBLICATION: Not applicable. COMPETING 
      INTERESTS: The authors declare that they have no competing interests. PUBLISHER'S 
      NOTE: Springer Nature remains neutral with regard to jurisdictional claims in 
      published maps and institutional affiliations.
EDAT- 2019/02/15 06:00
MHDA- 2019/07/06 06:00
PMCR- 2019/02/13
CRDT- 2019/02/15 06:00
PHST- 2018/06/01 00:00 [received]
PHST- 2019/01/10 00:00 [accepted]
PHST- 2019/02/15 06:00 [entrez]
PHST- 2019/02/15 06:00 [pubmed]
PHST- 2019/07/06 06:00 [medline]
PHST- 2019/02/13 00:00 [pmc-release]
AID - 10.1186/s13063-019-3192-z [pii]
AID - 3192 [pii]
AID - 10.1186/s13063-019-3192-z [doi]
PST - epublish
SO  - Trials. 2019 Feb 13;20(1):128. doi: 10.1186/s13063-019-3192-z.