PMID- 30761721
OWN - NLM
STAT- MEDLINE
DCOM- 20200106
LR  - 20200106
IS  - 1520-7560 (Electronic)
IS  - 1520-7552 (Linking)
VI  - 35
IP  - 4
DP  - 2019 May
TI  - The risk of mortality among people with type 2 diabetes in Latin America: A 
      systematic review and meta-analysis of population-based cohort studies.
PG  - e3139
LID - 10.1002/dmrr.3139 [doi]
AB  - Type 2 diabetes mellitus (T2DM) is associated with a high mortality risk, 
      although the magnitude of this association remains unknown in Latin America (LA). 
      We aimed to assess the strength of the association between T2DM and all-cause and 
      cause-specific mortality in population-based cohort studies in LA. Systematic 
      review and meta-analysis: inclusion criteria were (1) men and women 18 years old 
      and above with T2DM; (2) study outcomes all-cause and/or cause-specific 
      mortality; and (3) using people without T2DM as comparison group. Five databases 
      (Scopus, Medline, Embase, Global Health, and LILACS) were searched. Risk of bias 
      was evaluated with the ROBINS-I criteria. Initially, there were 979 identified 
      studies, of which 17 were selected for qualitative synthesis; 14 were included in 
      the meta-analysis (N = 416 821). Self-reported T2DM showed a pooled relative risk 
      (RR) of 2.49 for all-causes mortality (I-squared [I(2) ] = 85.7%, p < 0.001; 95% 
      confidence interval [CI], 1.96-3.15). T2DM based on a composite definition was 
      associated with a 2.26-fold higher all-cause mortality (I(2)  = 93.9%, p < 0.001; 
      95% CI, 1.36-3.74). The pooled risk estimates were similar between men and women, 
      although higher at younger ages. The pooled RR for cardiovascular mortality was 
      2.76 (I(2)  = 59.2%; p < 0.061; 95% CI, 1.99-3.82) and for renal mortality 15.85 
      (I(2)  = 0.00%; p < 0.645; 95% CI, 9.82-25.57). Using available population-based 
      cohort studies, this work has identified and estimated the strength of the 
      association between T2DM and mortality in LA. The higher mortality risk compared 
      with high-income countries deserves close attention from health policies makers 
      and clinicians to improve diabetes care and control hence preventing 
      complications and delaying death.
CI  - (c) 2019 John Wiley & Sons, Ltd.
FAU - Carrillo-Larco, Rodrigo M
AU  - Carrillo-Larco RM
AUID- ORCID: 0000-0002-2090-1856
AD  - Department of Epidemiology and Biostatistics, School of Public Health, Imperial 
      College London, London, UK.
AD  - CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano 
      Heredia, Lima, Peru.
FAU - Barengo, Noel C
AU  - Barengo NC
AD  - Department of Medical and Population Health Sciences Research, Herbert Wertheim 
      College of Medicine, Florida International University, Miami, FL, USA.
AD  - Department of Public Health, University of Helsinki, Helsinki, Finland.
FAU - Albitres-Flores, Leonardo
AU  - Albitres-Flores L
AD  - CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano 
      Heredia, Lima, Peru.
AD  - Facultad de Medicina, Universidad Nacional de Trujillo, Trujillo, Peru.
AD  - Sociedad Cientifica de Estudiantes de Medicina de la Universidad Nacional de 
      Trujillo-SOCEMUNT, Trujillo, Peru.
FAU - Bernabe-Ortiz, Antonio
AU  - Bernabe-Ortiz A
AUID- ORCID: 0000-0002-6834-1376
AD  - CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano 
      Heredia, Lima, Peru.
AD  - Facultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas, 
      Lima, Peru.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Systematic Review
DEP - 20190304
PL  - England
TA  - Diabetes Metab Res Rev
JT  - Diabetes/metabolism research and reviews
JID - 100883450
SB  - IM
MH  - Cohort Studies
MH  - Diabetes Mellitus, Type 2/*epidemiology/*mortality
MH  - Humans
MH  - Latin America/epidemiology
MH  - Prevalence
MH  - Prognosis
MH  - Survival Rate
OTO - NOTNLM
OT  - Latin America
OT  - cohort studies
OT  - diabetes
OT  - mortality
EDAT- 2019/02/15 06:00
MHDA- 2020/01/07 06:00
CRDT- 2019/02/15 06:00
PHST- 2019/01/04 00:00 [received]
PHST- 2019/02/06 00:00 [revised]
PHST- 2019/02/11 00:00 [accepted]
PHST- 2019/02/15 06:00 [pubmed]
PHST- 2020/01/07 06:00 [medline]
PHST- 2019/02/15 06:00 [entrez]
AID - 10.1002/dmrr.3139 [doi]
PST - ppublish
SO  - Diabetes Metab Res Rev. 2019 May;35(4):e3139. doi: 10.1002/dmrr.3139. Epub 2019 
      Mar 4.