PMID- 30762815 OWN - NLM STAT- MEDLINE DCOM- 20190314 LR - 20221005 IS - 1536-5964 (Electronic) IS - 0025-7974 (Print) IS - 0025-7974 (Linking) VI - 98 IP - 7 DP - 2019 Feb TI - Electrical stimulation on adverse events caused by chemotherapy in patients with cervical cancer: A protocol for a systematic review of randomized controlled trial. PG - e14609 LID - 10.1097/MD.0000000000014609 [doi] LID - e14609 AB - BACKGROUND: This protocol of systematic review aims to investigate the effectiveness of electrical stimulation (ES) on adverse events (AEs) caused by chemotherapy in patients with cervical cancer (CC). METHODS: This systematic review of randomized controlled trials will be identified through searchers of PUBMED, PsycINFO, Scopus, Opengrey, Cochrane Central Register of Controlled Trials, EMBASE, Cumulative Index to Nursing and Allied Health Literature, Web of Science, Allied and Complementary Medicine Database, and Chinese Biomedical Literature Database. All the sources will be searched from the inception to the date of study search ran. Additionally, websites of clinical trials registry and reference lists provided in relevant studies and reviews will also be searched. Two independent reviewers will evaluate the eligibility criteria of all potential literature, extract the data, and determine the risk of bias for each included study. RevMan 5.3 software will be used to pool the data and to conduct a meta-analysis. RESULTS: This systematic review will assess the effectiveness of ES on AEs caused by chemotherapy in patients with CC. CONCLUSION: The findings of this study may summarize the latest evidence for the ES on AEs following chemotherapy for CC. PROSPERO REGISTRATION NUMBER: PROSPERO CRD42019120191. FAU - Dou, Peng-Hui AU - Dou PH AD - Department of Radiotherapy and Chemotherapy. FAU - Zhang, Dan-Feng AU - Zhang DF AD - Department of Gynecology. FAU - Su, Cui-Hong AU - Su CH AD - Department of Gynecology. FAU - Zhang, Xiao-Li AU - Zhang XL AD - Department of Scientific Research, First Affiliated Hospital of Jiamusi University, Jiamusi, China. FAU - Wu, Ying-Jie AU - Wu YJ AD - Department of Gynecology. LA - eng PT - Journal Article PT - Review PL - United States TA - Medicine (Baltimore) JT - Medicine JID - 2985248R RN - 0 (Antineoplastic Agents) SB - IM MH - Antineoplastic Agents/*adverse effects/therapeutic use MH - Diarrhea/chemically induced/therapy MH - Electric Stimulation Therapy/*methods MH - Fatigue/chemically induced/therapy MH - Female MH - Humans MH - Nausea/chemically induced/therapy MH - Pain/chemically induced MH - Randomized Controlled Trials as Topic MH - Research Design MH - Uterine Cervical Neoplasms/*drug therapy MH - Vomiting/chemically induced/therapy PMC - PMC6408053 COIS- The authors have no conflicts of interest to disclose. EDAT- 2019/02/15 06:00 MHDA- 2019/03/15 06:00 PMCR- 2019/02/15 CRDT- 2019/02/15 06:00 PHST- 2019/02/15 06:00 [entrez] PHST- 2019/02/15 06:00 [pubmed] PHST- 2019/03/15 06:00 [medline] PHST- 2019/02/15 00:00 [pmc-release] AID - 00005792-201902150-00092 [pii] AID - MD-D-19-00771 [pii] AID - 10.1097/MD.0000000000014609 [doi] PST - ppublish SO - Medicine (Baltimore). 2019 Feb;98(7):e14609. doi: 10.1097/MD.0000000000014609.