PMID- 30764886 OWN - NLM STAT- MEDLINE DCOM- 20200330 LR - 20200330 IS - 2523-3106 (Electronic) IS - 2523-3106 (Linking) VI - 59 IP - 1 DP - 2019 Feb 14 TI - Axial Spondyloarthritis after bariatric surgery: a 7-year retrospective analysis. PG - 8 LID - 10.1186/s42358-019-0050-3 [doi] AB - BACKGROUND: In recent decades, obesity has become a public health problem in many countries. The objective of this study was to evaluate the main joint and extra-articular manifestations related to spondyloarthritis (SpA) after bariatric surgery (BS) in a retrospective cohort. METHODS: Demographic, clinical, laboratory and imaging data from nine patients whose SpA symptoms started after a BS have been described. Modified New York (mNY) criteria for ankylosing spondylitis (AS) and the Assessment of Spondyloarthritis International Society (ASAS) criteria for axial (ax-SpA) and peripheral (p-SpA) spondyloarthritis were applied. RESULTS: The mean weight reduction after BS was 49.3 +/- 21.9 kg. The BS techniques were Roux-en-Y gastric bypass (n = 8; 88.9%) and biliopancreatic diversion with duodenal switch (n = 1; 11.1%). Four (44.4%) patients had no axial or peripheral pain complaints before BS, while the other four (44.4%) had sporadic non-inflammatory back pain that had been attributed to obesity. One patient (11.1%) had persistent chronic back pain. In all nine cases, patients reported back pain onset or pattern (intensity or night pain) change after BS (mean time 14.7 +/- 18 months). In addition, 8 of them (88.9%) were human leukocyte antigen (HLA)-B27 positive. All nine patients could be classified according to ASAS criteria as ax-SpA and five (55.6%) patients were classified as AS, according to the mNY criteria. CONCLUSION: Our data highlight a temporal link between SpA onset symptoms and the BS, suggesting a possible causal plausibility between the two events. FAU - de Oliveira, Thauana Luiza AU - de Oliveira TL AUID- ORCID: 0000-0001-8028-9497 AD - Rheumatology Division, Spondyloarthritis Section, Universidade Federal de Sao Paulo, Rua Leandro Dupre, 204, Conjunto 74, Vila Clementino, Sao Paulo, SP, CEP 04025-010, Brazil. thauanareumato@gmail.com. FAU - Libanori, Hilton Telles AU - Libanori HT AD - Hospital Israelita Albert Einstein, Sao Paulo, Brazil. FAU - Pinheiro, Marcelo M AU - Pinheiro MM AD - Rheumatology Division, Spondyloarthritis Section, Universidade Federal de Sao Paulo, Rua Leandro Dupre, 204, Conjunto 74, Vila Clementino, Sao Paulo, SP, CEP 04025-010, Brazil. LA - eng PT - Journal Article DEP - 20190214 PL - England TA - Adv Rheumatol JT - Advances in rheumatology (London, England) JID - 101734172 RN - 0 (HLA-B27 Antigen) SB - IM MH - Adult MH - Age of Onset MH - Back Pain/etiology MH - Bariatric Surgery/*adverse effects/methods MH - Chronic Pain/etiology MH - Female MH - HLA-B27 Antigen/blood MH - Humans MH - Male MH - Middle Aged MH - Obesity/complications MH - Pain, Postoperative/blood/*etiology MH - Retrospective Studies MH - Spondylarthritis/blood/*etiology MH - Weight Loss OTO - NOTNLM OT - Bariatric surgery OT - HLA-B27 OT - Spondyloarthritis EDAT- 2019/02/16 06:00 MHDA- 2020/03/31 06:00 CRDT- 2019/02/16 06:00 PHST- 2018/08/24 00:00 [received] PHST- 2019/01/30 00:00 [accepted] PHST- 2019/02/16 06:00 [entrez] PHST- 2019/02/16 06:00 [pubmed] PHST- 2020/03/31 06:00 [medline] AID - 10.1186/s42358-019-0050-3 [pii] AID - 10.1186/s42358-019-0050-3 [doi] PST - epublish SO - Adv Rheumatol. 2019 Feb 14;59(1):8. doi: 10.1186/s42358-019-0050-3.