PMID- 30766553
OWN - NLM
STAT- MEDLINE
DCOM- 20190610
LR  - 20220331
IS  - 1729-0503 (Electronic)
IS  - 1680-6905 (Print)
IS  - 1680-6905 (Linking)
VI  - 18
IP  - 4
DP  - 2018 Dec
TI  - Effects of gender, age and treatment duration on lipid profile and renal function 
      indices in diabetic patients attending a teaching hospital in South-Western 
      Nigeria.
PG  - 900-908
LID - 10.4314/ahs.v18i4.8 [doi]
AB  - BACKGROUND: Type 2 Diabetes Mellitus (T2DM) is associated with diabetic 
      nephropathy and hyperlipidemia. Gender, age, medication adherence, lifestyle, 
      culture and socioeconomic status could be sources of diversity in T2DM leading to 
      differences in predisposition, development and clinical presentation. OBJECTIVES: 
      Therefore, this study aimed to investigate the influence of gender, age and 
      treatment duration on kidney and lipid-related biochemical indices of T2DM 
      patients attending Ekiti State University Teaching Hospital, Ado-Ekiti, Nigeria 
      (EKSUTH). METHODS: Blood from diabetic patients and healthy subjects was analysed 
      for fasting blood glucose (FBG), renal function parameters and lipid profile. 
      Influence of age, gender and treatment duration on indices was assessed using 
      standard baseline values. RESULTS: Dyslipidemia was pronounced among female 
      diabetics while the incidence of diabetes was found to be higher in middle-age. 
      The percentage of diabetics with high levels of FPG, urea, creatinine, 
      cholesterol, triglyceride and low density lipoprotein-cholesterol after 9-10 
      years of treatment were lower compared with the percentage after 5-6 years of 
      treatment. CONCLUSION: Gender, age and treatment duration influenced clinical 
      course of T2DM among patients presenting at EKSUTH but long term treatment 
      appeared to improve T2DM among patients.
FAU - Aderibigbe, Mary Alaba
AU  - Aderibigbe MA
AD  - Department of Biochemistry, School of Sciences, The Federal University of 
      Technology, P.M.B. 704, Akure, Nigeria.
FAU - Obafemi, Tajudeen Olabisi
AU  - Obafemi TO
AD  - Department of Biochemistry, School of Sciences, The Federal University of 
      Technology, P.M.B. 704, Akure, Nigeria.
FAU - Olaleye, Mary Tolulope
AU  - Olaleye MT
AD  - Department of Biochemistry, School of Sciences, The Federal University of 
      Technology, P.M.B. 704, Akure, Nigeria.
FAU - Akinmoladun, Afolabi Clement
AU  - Akinmoladun AC
AD  - Department of Biochemistry, School of Sciences, The Federal University of 
      Technology, P.M.B. 704, Akure, Nigeria.
LA  - eng
PT  - Journal Article
PL  - Uganda
TA  - Afr Health Sci
JT  - African health sciences
JID - 101149451
RN  - 0 (Blood Glucose)
RN  - 0 (Hypoglycemic Agents)
RN  - 0 (Hypolipidemic Agents)
RN  - 0 (Lipids)
SB  - IM
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Aged, 80 and over
MH  - Blood Glucose
MH  - Body Mass Index
MH  - Case-Control Studies
MH  - Diabetes Mellitus, Type 2/*blood/drug therapy/*epidemiology
MH  - Dyslipidemias/*blood/drug therapy/*epidemiology
MH  - Female
MH  - Hospitals, Teaching
MH  - Humans
MH  - Hypoglycemic Agents/therapeutic use
MH  - Hypolipidemic Agents/therapeutic use
MH  - Kidney Function Tests
MH  - Lipids/blood
MH  - Male
MH  - Middle Aged
MH  - Nigeria/epidemiology
MH  - Sex Factors
MH  - Time Factors
PMC - PMC6354870
OTO - NOTNLM
OT  - Ekiti State
OT  - Fasting blood glucose
OT  - atherogenic index
OT  - creatinine
OT  - diabetes
OT  - dyslipidemia
EDAT- 2019/02/16 06:00
MHDA- 2019/06/14 06:00
PMCR- 2018/12/01
CRDT- 2019/02/16 06:00
PHST- 2019/02/16 06:00 [entrez]
PHST- 2019/02/16 06:00 [pubmed]
PHST- 2019/06/14 06:00 [medline]
PHST- 2018/12/01 00:00 [pmc-release]
AID - jAFHS.v18.i4.pg900 [pii]
AID - 10.4314/ahs.v18i4.8 [doi]
PST - ppublish
SO  - Afr Health Sci. 2018 Dec;18(4):900-908. doi: 10.4314/ahs.v18i4.8.