PMID- 30772467
OWN - NLM
STAT- MEDLINE
DCOM- 20190610
LR  - 20190613
IS  - 1878-3511 (Electronic)
IS  - 1201-9712 (Linking)
VI  - 81
DP  - 2019 Apr
TI  - Candida Tropicalis renal microabscesses in a child with leukemia confirmed using 
      nucleic acid amplification and recovery after prolonged antifungal and 
      corticosteroid treatment.
PG  - 110-113
LID - S1201-9712(19)30066-9 [pii]
LID - 10.1016/j.ijid.2019.02.002 [doi]
AB  - We report the first case of microabscesses detected by polymerase chain reaction 
      (PCR) amplification of nucleic acid from ultrasound-guided aspirated fluid in a 
      three-year old boy with acute lymphoblastic leukemia and febrile neutropenia 
      during induction chemotherapy. Fever persisted despite effective antifungal 
      treatment. The addition of corticosteroid therapy successfully controlled the 
      suspected immune reconstitution inflammatory syndrome (IRIS). This case 
      highlights the utility of PCR and adjunctive corticosteroid in the approach of 
      Candida tropicalis renal microabscesses in leukemic patients undergoing 
      chemotherapy.
CI  - Copyright (c) 2019 The Author(s). Published by Elsevier Ltd.. All rights reserved.
FAU - Rosa Duque, Jaime S
AU  - Rosa Duque JS
AD  - Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Li Ka 
      Shing Faculty of Medicine, The University of Hong Kong, Hong Kong. Electronic 
      address: jsrduque@hku.hk.
FAU - To, Kelvin K W
AU  - To KKW
AD  - Department of Microbiology, Queen Mary Hospital, Li Ka Shing Faculty of Medicine, 
      The University of Hong Kong, Hong Kong.
FAU - Chiang, Alan K S
AU  - Chiang AKS
AD  - Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Li Ka 
      Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.
FAU - Chan, Godfrey C F
AU  - Chan GCF
AD  - Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Li Ka 
      Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.
FAU - Poon, Rosana W S
AU  - Poon RWS
AD  - Department of Microbiology, Queen Mary Hospital, Li Ka Shing Faculty of Medicine, 
      The University of Hong Kong, Hong Kong.
FAU - Yuen, Kwok-Yung
AU  - Yuen KY
AD  - Department of Microbiology, Queen Mary Hospital, Li Ka Shing Faculty of Medicine, 
      The University of Hong Kong, Hong Kong.
FAU - Ha, Shau-Yin
AU  - Ha SY
AD  - Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Li Ka 
      Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.
FAU - Cheuk, Daniel K L
AU  - Cheuk DKL
AD  - Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Li Ka 
      Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20190214
PL  - Canada
TA  - Int J Infect Dis
JT  - International journal of infectious diseases : IJID : official publication of the 
      International Society for Infectious Diseases
JID - 9610933
RN  - 0 (Adrenal Cortex Hormones)
RN  - 0 (Antifungal Agents)
SB  - IM
MH  - Abscess/*drug therapy
MH  - Adrenal Cortex Hormones/*therapeutic use
MH  - Antifungal Agents/*therapeutic use
MH  - *Candida tropicalis
MH  - Candidiasis/*drug therapy
MH  - Child, Preschool
MH  - Humans
MH  - Kidney Diseases/*drug therapy
MH  - Male
MH  - Nucleic Acid Amplification Techniques/*methods
MH  - Precursor Cell Lymphoblastic Leukemia-Lymphoma/complications/*drug therapy
MH  - Ultrasonography, Interventional
OTO - NOTNLM
OT  - Candida
OT  - Leukemia
OT  - Nucleic acid amplification
OT  - Polymerase chain reaction
OT  - Renal abscess
EDAT- 2019/02/18 06:00
MHDA- 2019/06/14 06:00
CRDT- 2019/02/18 06:00
PHST- 2018/11/28 00:00 [received]
PHST- 2019/02/01 00:00 [revised]
PHST- 2019/02/08 00:00 [accepted]
PHST- 2019/02/18 06:00 [pubmed]
PHST- 2019/06/14 06:00 [medline]
PHST- 2019/02/18 06:00 [entrez]
AID - S1201-9712(19)30066-9 [pii]
AID - 10.1016/j.ijid.2019.02.002 [doi]
PST - ppublish
SO  - Int J Infect Dis. 2019 Apr;81:110-113. doi: 10.1016/j.ijid.2019.02.002. Epub 2019 
      Feb 14.