PMID- 30774324
OWN - NLM
STAT- MEDLINE
DCOM- 20190729
LR  - 20231005
IS  - 1178-2005 (Electronic)
IS  - 1176-9106 (Print)
IS  - 1176-9106 (Linking)
VI  - 14
DP  - 2019
TI  - Minimal clinically important difference of 3-minute chair rise test and the 
      DIRECT questionnaire after pulmonary rehabilitation in COPD patients.
PG  - 261-269
LID - 10.2147/COPD.S187567 [doi]
AB  - BACKGROUND: The 3-minute chair rise test (3-minute CRT) and the Disability 
      Related to COPD Tool (DIRECT) are two reproducible and valid short tests that can 
      assess the benefit of pulmonary rehabilitation (PR) in terms of functional 
      capacity and dyspnea in everyday activities. METHODS: We determined the minimal 
      clinically important difference (MCID) of the DIRECT questionnaire and 3-minute 
      CRT using distribution methods and anchor encroaches with a panel of eight 
      standard tests in a cohort of 116 COPD patients who completed a PR program in 
      real-life settings. RESULTS: The estimated MCID for the 3-minute CRT and DIRECT 
      scores was five repetitions and two units, respectively, using separate and 
      combined independent anchors. The all-patient (body mass 
      index-obstruction-dyspnea-exercise [BODE] scores 0-7), BODE 0-2 (n=42), and BODE 
      3-4 (n=50) groups showed improvements greater than the MCID in most tests and 
      questionnaires used. In contrast, the BODE 5-7 group (n=24) showed improvements 
      greater than MCID in only the 3-minute CRT, 6-minute walk test, endurance 
      exercise test, and DIRECT questionnaire. DISCUSSION AND CONCLUSION: This study 
      demonstrates that the short and simple DIRECT questionnaire and 3-minute CRT are 
      responsive to capture the beneficial effects of a PR program in COPD patients, 
      including those with severe disease. TRIAL REGISTRATION NUMBER: NCT03286660.
FAU - Levesque, Jonathan
AU  - Levesque J
AD  - Department of Medicine, Pneumology Service, Hopital Maisonneuve-Rosemont, Faculty 
      of Medicine, Universite de Montreal, Montreal, Quebec, Canada.
FAU - Antoniadis, Anestis
AU  - Antoniadis A
AD  - Laboratoire Jean Kuntzmann UMR5224, Statistics Department, Universite 
      Grenoble-Alpes, Grenoble, France.
FAU - Li, Pei Zhi
AU  - Li PZ
AD  - Montreal Chest Institute, McGill University Health Center Research Institute, 
      McGill University, Montreal, Quebec, Canada.
FAU - Herengt, Frederic
AU  - Herengt F
AD  - Centre de Readaptation Cardio-Respiratoire-Dieulefit Sante, Dieulefit, France.
FAU - Brosson, Christophe
AU  - Brosson C
AD  - Private Physiotherapist, Cours Liberation, Grenoble, France.
FAU - Grosbois, Jean-Marie
AU  - Grosbois JM
AD  - Pneumology Service, Centre Hospitalier de Bethune, Bethune, France.
FAU - Bernady, Alain
AU  - Bernady A
AD  - Toki-Eder Centre Medical Cardio-Respiratoire, Cambo-les-Bains, France.
FAU - Bender, Anthony
AU  - Bender A
AD  - Private Physiotherapist, Boulevard de Metz Mont-Saint-Martin, France.
AD  - LUNEX International University of Health, Exercise and Sports, Differdange, 
      Luxembourg.
FAU - Favre, Murielle
AU  - Favre M
AD  - Centre de Pneumologie Henri Bazire, Saint-Julien-de-Ratz, France.
FAU - Guerder, Antoine
AU  - Guerder A
AD  - AP-HP, Groupe Hospitalier Pitie-Salpetriere Charles Foix, Service de Pneumologie, 
      Medecine Intensive et Reanimation, Departement R3S, Paris, France.
FAU - Surpas, Pascale
AU  - Surpas P
AD  - Centre Medical de Bayere, Charnay, France.
FAU - Similowski, Thomas
AU  - Similowski T
AD  - AP-HP, Groupe Hospitalier Pitie-Salpetriere Charles Foix, Service de Pneumologie, 
      Medecine Intensive et Reanimation, Departement R3S, Paris, France.
AD  - Sorbonne Universite, INSERM, UMRS1158 Neurophysiologie Respiratoire Experimentale 
      et Clinique, Paris, France.
FAU - Aguilaniu, Bernard
AU  - Aguilaniu B
AD  - Faculty of Medicine, Universite Grenoble-Alpes, Grenoble, France, 
      b.aguilaniu@icloud.com.
LA  - eng
SI  - ClinicalTrials.gov/NCT03286660
PT  - Comparative Study
PT  - Journal Article
PT  - Multicenter Study
PT  - Observational Study
DEP - 20190122
PL  - New Zealand
TA  - Int J Chron Obstruct Pulmon Dis
JT  - International journal of chronic obstructive pulmonary disease
JID - 101273481
MH  - Activities of Daily Living
MH  - Aged
MH  - *Disability Evaluation
MH  - Europe
MH  - *Exercise Test
MH  - Exercise Tolerance
MH  - Female
MH  - Health Status
MH  - Humans
MH  - Lung/*physiopathology
MH  - Male
MH  - Middle Aged
MH  - *Minimal Clinically Important Difference
MH  - Predictive Value of Tests
MH  - Prospective Studies
MH  - Pulmonary Disease, Chronic Obstructive/*diagnosis/physiopathology/*rehabilitation
MH  - Quebec
MH  - Recovery of Function
MH  - Severity of Illness Index
MH  - *Surveys and Questionnaires
MH  - Time Factors
MH  - Treatment Outcome
MH  - Walk Test
PMC - PMC6349077
OTO - NOTNLM
OT  - COPD
OT  - MCID
OT  - chair tests
OT  - outcomes assessment
OT  - pulmonary rehabilitation
OT  - tools
COIS- Disclosure Financial support for this study was provided by an unrestricted grant 
      from Boehringer Ingelheim, France. BA reports grants and other from Boehringer 
      Ingelheim, France, during the conduct of the study. The authors report no other 
      conflicts of interest in this work.
EDAT- 2019/02/19 06:00
MHDA- 2019/07/30 06:00
PMCR- 2019/01/22
CRDT- 2019/02/19 06:00
PHST- 2019/02/19 06:00 [entrez]
PHST- 2019/02/19 06:00 [pubmed]
PHST- 2019/07/30 06:00 [medline]
PHST- 2019/01/22 00:00 [pmc-release]
AID - copd-14-261 [pii]
AID - 10.2147/COPD.S187567 [doi]
PST - epublish
SO  - Int J Chron Obstruct Pulmon Dis. 2019 Jan 22;14:261-269. doi: 
      10.2147/COPD.S187567. eCollection 2019.