PMID- 30789437
OWN - NLM
STAT- Publisher
LR  - 20240227
IS  - 1530-0315 (Electronic)
IS  - 0195-9131 (Linking)
DP  - 2019 Feb 15
TI  - Individual Response to Standardized Exercise: Total and Abdominal Adipose Tissue.
LID - 10.1249/MSS.0000000000001930 [doi]
AB  - PURPOSE: (1) Determine the effect of exercise amount and intensity on the 
      proportion of adipose tissue (AT) responses likely, very likely, and unlikely 
      above the minimal clinically important difference (MCID); and (2) Examine whether 
      clinically meaningful anthropometric changes reflect individual AT responses 
      above the MCID. METHODS: Men (n=41) and women (n=62) (52.7 +/- 7.6 years) were 
      randomized to control (N=20); low amount low intensity (LALI, N=24); high amount 
      low intensity (HALI, N=30); and high amount high intensity (HAHI, N=29) exercise 
      for 24 weeks. AT changes were measured by MRI. The probability that individual 
      responses were > MCID after adjusting for technical error of measurement were 
      calculated for each individual and categorized as: 'Unlikely' = < 25%, 'Possibly' 
      = 25-74%, 'Likely' = 75-94%, 'Very Likely' = 95-100% chance. RESULTS: The HALI 
      (total AT) and HAHI (total AT, visceral AT) groups had a greater proportion of 
      individuals whose response was "very likely" >/= MCID vs controls (p<0.006). Across 
      the abdominal AT depots, for individuals who reduced WC or body weight >/= 2 cm or 
      2 kg, respectively, 51-69% of responses were "likely" or "very likely" beyond the 
      MCID. CONCLUSION: Increasing exercise amount and/or intensity may increase the 
      proportion of individuals deemed 'very likely' to achieve clinically meaningful 
      AT reductions. The use of anthropometric change to identify individual response 
      for adiposity reduction remains a challenge.
FAU - Brennan, Andrea M
AU  - Brennan AM
AD  - School of Kinesiology and Health Studies, Queen's University, Kingston, ON, 
      Canada.
FAU - Day, Andrew G
AU  - Day AG
AD  - School of Medicine, Department of Endocrinology and Metabolism, Queen's 
      University, Kingston, Ontario, Canada.
AD  - Department of Public Health Sciences, Queen's University, Kingston, ON, Canada.
FAU - Cowan, Theresa E
AU  - Cowan TE
AD  - School of Kinesiology and Health Studies, Queen's University, Kingston, ON, 
      Canada.
FAU - Clarke, Gregory J
AU  - Clarke GJ
AD  - School of Kinesiology and Health Studies, Queen's University, Kingston, ON, 
      Canada.
FAU - Lamarche, Benoit
AU  - Lamarche B
AD  - Institute of Nutraceuticals and Functional Foods, Laval University, Quebec City, 
      Quebec, Canada.
FAU - Ross, Robert
AU  - Ross R
AD  - School of Kinesiology and Health Studies, Queen's University, Kingston, ON, 
      Canada.
AD  - Kingston General Health Research Institute, Kingston, Ontario, Canada.
LA  - eng
PT  - Journal Article
DEP - 20190215
PL  - United States
TA  - Med Sci Sports Exerc
JT  - Medicine and science in sports and exercise
JID - 8005433
EDAT- 2019/02/23 06:00
MHDA- 2019/02/23 06:00
CRDT- 2019/02/22 06:00
PHST- 2019/02/22 06:00 [entrez]
PHST- 2019/02/23 06:00 [pubmed]
PHST- 2019/02/23 06:00 [medline]
AID - 10.1249/MSS.0000000000001930 [doi]
PST - aheadofprint
SO  - Med Sci Sports Exerc. 2019 Feb 15. doi: 10.1249/MSS.0000000000001930.