PMID- 30813181
OWN - NLM
STAT- MEDLINE
DCOM- 20190311
LR  - 20200225
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 98
IP  - 8
DP  - 2019 Feb
TI  - Therapeutic efficacy of extracorporeal shock wave combined with hyaluronic acid 
      on knee osteoarthritis.
PG  - e14589
LID - 10.1097/MD.0000000000014589 [doi]
LID - e14589
AB  - This retrospective study investigated the efficacy and safety of extracorporeal 
      shock wave (EPSW) combined with hyaluronic acid (HA) for patients with knee 
      osteoarthritis (KOA).This retrospective study included 70 patients with KOA. Of 
      those subjects, 35 of them received EPSW combined HA, and were allocated to a 
      treatment group, while the other 35 participants received HA alone and were 
      allocated to a control group. Patients in both groups were treated for a total of 
      8 weeks. The primary outcome was measured by visual analog scale (VAS). The 
      secondary outcomes were measured by Western Ontario and McMaster Universities 
      Osteoarthritis Index (WOMAC), and knee injury and osteoarthritis outcome score 
      (KOOS). In addition, adverse events (AEs) were also evaluated. All outcomes were 
      measured before and after the treatment.After the treatment, patients in the 
      treatment group exhibited better efficacy in VAS (P < .01), WOMAC scale (pain, 
      P < .01; function, P < .01; and stiffness, P < .01), and KOOS scores (pain, 
      P < .01; function in daily living, P < .01; symptoms, P < .01; sport and 
      recreation, P < .01; and quality of life, P < .01), than patients in the control 
      group. In addition, no significant differences regarding the AEs were found 
      between 2 groups.The findings of this study demonstrated that the efficacy of 
      EPSW combined with HA is superior to the HA alone for patients with KOA.
FAU - Liu, Shi-Chen
AU  - Liu SC
AD  - First Ward of Orthopedics Department.
FAU - Qiao, Xiao-Feng
AU  - Qiao XF
AD  - First Ward of Orthopedics Department.
FAU - Tang, Qing-Xi
AU  - Tang QX
AD  - Department of Emergency Surgery, First Affiliated Hospital of Jiamusi University.
FAU - Li, Xiao-Guang
AU  - Li XG
AD  - Department of Orthodonitics, Affiliated Stomatological Hospital of Jiamusi 
      University, Jiamusi.
FAU - Yang, Jian-Hua
AU  - Yang JH
AD  - Department of Orthopedics, People's Hospital of Longgang District, Shenzhen, 
      Guangdong, China.
FAU - Wang, Tian-Qi
AU  - Wang TQ
AD  - First Ward of Orthopedics Department.
FAU - Xiao, Ya-Jie
AU  - Xiao YJ
AD  - First Ward of Orthopedics Department.
FAU - Qiao, Jian-Min
AU  - Qiao JM
AD  - First Ward of Orthopedics Department.
LA  - eng
PT  - Journal Article
PT  - Observational Study
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Viscosupplements)
RN  - 9004-61-9 (Hyaluronic Acid)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Combined Modality Therapy
MH  - Extracorporeal Shockwave Therapy/adverse effects/*methods
MH  - Female
MH  - Humans
MH  - Hyaluronic Acid/*administration & dosage/adverse effects
MH  - Injections, Intra-Articular
MH  - Knee Joint/physiopathology
MH  - Male
MH  - Middle Aged
MH  - Osteoarthritis, Knee/*therapy
MH  - Pain Measurement
MH  - Quality of Life
MH  - Retrospective Studies
MH  - Severity of Illness Index
MH  - Treatment Outcome
MH  - Viscosupplements/*administration & dosage/adverse effects
PMC - PMC6408132
COIS- The authors have no conflicts of interest to disclose.
EDAT- 2019/03/01 06:00
MHDA- 2019/03/12 06:00
PMCR- 2019/02/22
CRDT- 2019/03/01 06:00
PHST- 2019/03/01 06:00 [entrez]
PHST- 2019/03/01 06:00 [pubmed]
PHST- 2019/03/12 06:00 [medline]
PHST- 2019/02/22 00:00 [pmc-release]
AID - 00005792-201902220-00061 [pii]
AID - MD-D-19-00235 [pii]
AID - 10.1097/MD.0000000000014589 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2019 Feb;98(8):e14589. doi: 10.1097/MD.0000000000014589.