PMID- 30814962 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 1664-0640 (Print) IS - 1664-0640 (Electronic) IS - 1664-0640 (Linking) VI - 10 DP - 2019 TI - Psychoeducational Intervention for Perinatal Depression: Study Protocol of a Randomized Controlled Trial. PG - 55 LID - 10.3389/fpsyt.2019.00055 [doi] LID - 55 AB - Perinatal depression (PD) is a severe and disabling condition impacting negatively on children in terms of adverse neonatal outcomes and on the well-being of women and their families. All pregnant women attending the unit of Gynecology and Obstetrics Service of the University of Campania "L. Vanvitelli" will be screened for PD using the Edinburgh Postpartum Depression Scale (EPDS). Women with a score >/=10 at the EPDS will be invited to receive a full psychiatric assessment. The required sample size is of 126 women with PD which will be randomly allocated to either an experimental group, receiving a uni-familiar psychoeducational intervention, or to a control group, receiving the Best Treatment Option (BTO). Patients will be evaluated through several assessment instruments: Hamilton Depression Rating Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A), Global Assessment of Functioning (GAF), Clinical Global Impression (CGI), Manchester Short Assessment of Quality of Life (MANSA), Family Assessment Device (FAD), Family Coping Questionnaire (FCQ), and Pattern of Care Schedule (PCS). Patients will be evaluated at baseline, 3, 6, 9, and 12 months post-randomization. The severity of depressive symptoms at the HAM-D scale has been selected as primary outcome. Other outcome measures include improvement in the severity of anxiety symptoms, of global and personal functioning, an improvement in family members' coping strategies and in the level of quality of life. It has been highlighted the importance of developing screening and treating programs for PD, and our study will use rigorous study design to evaluate the efficacy of the adaption of a well-known family psychoeducational model to the treatment of PD. The aims of present trial are to: (1) develop an informative package for pregnant women with PD; (2) promote a screening programme for PD; (3) identify those (socio-demographic and pregnancy-related environmental) factors associated with a higher risk to develop a perinatal or postnatal depression; (4) evaluate the efficacy of a new experimental psychoeducational intervention in reducing the depressive symptoms during pregnancy compared to the BTO. FAU - Steardo, Luca Jr AU - Steardo L Jr AD - Department of Psychiatry, University of Campania Luigi Vanvitelli, Naples, Italy. FAU - Caivano, Vito AU - Caivano V AD - Department of Psychiatry, University of Campania Luigi Vanvitelli, Naples, Italy. FAU - Sampogna, Gaia AU - Sampogna G AD - Department of Psychiatry, University of Campania Luigi Vanvitelli, Naples, Italy. FAU - Di Cerbo, Arcangelo AU - Di Cerbo A AD - Department of Psychiatry, University of Campania Luigi Vanvitelli, Naples, Italy. FAU - Fico, Giovanna AU - Fico G AD - Department of Psychiatry, University of Campania Luigi Vanvitelli, Naples, Italy. FAU - Zinno, Francesca AU - Zinno F AD - Department of Psychiatry, University of Campania Luigi Vanvitelli, Naples, Italy. FAU - Del Vecchio, Valeria AU - Del Vecchio V AD - Department of Psychiatry, University of Campania Luigi Vanvitelli, Naples, Italy. FAU - Giallonardo, Vincenzo AU - Giallonardo V AD - Department of Psychiatry, University of Campania Luigi Vanvitelli, Naples, Italy. FAU - Torella, Marco AU - Torella M AD - Department of Gynecology, University of Campania Luigi Vanvitelli, Naples, Italy. FAU - Luciano, Mario AU - Luciano M AD - Department of Psychiatry, University of Campania Luigi Vanvitelli, Naples, Italy. FAU - Fiorillo, Andrea AU - Fiorillo A AD - Department of Psychiatry, University of Campania Luigi Vanvitelli, Naples, Italy. LA - eng PT - Case Reports DEP - 20190213 PL - Switzerland TA - Front Psychiatry JT - Frontiers in psychiatry JID - 101545006 PMC - PMC6381058 OTO - NOTNLM OT - coping strategies OT - family burden OT - perinatal depression OT - severe mental disorders OT - women mental health EDAT- 2019/03/01 06:00 MHDA- 2019/03/01 06:01 PMCR- 2019/02/13 CRDT- 2019/03/01 06:00 PHST- 2018/09/03 00:00 [received] PHST- 2019/01/24 00:00 [accepted] PHST- 2019/03/01 06:00 [entrez] PHST- 2019/03/01 06:00 [pubmed] PHST- 2019/03/01 06:01 [medline] PHST- 2019/02/13 00:00 [pmc-release] AID - 10.3389/fpsyt.2019.00055 [doi] PST - epublish SO - Front Psychiatry. 2019 Feb 13;10:55. doi: 10.3389/fpsyt.2019.00055. eCollection 2019.