PMID- 30816974 OWN - NLM STAT- MEDLINE DCOM- 20190325 LR - 20190325 IS - 1460-2709 (Electronic) IS - 1369-3786 (Linking) VI - 57 IP - Supplement_2 DP - 2019 Apr 1 TI - Challenging cases in fungal asthma. PG - S110-S117 LID - 10.1093/mmy/myy063 [doi] AB - Fungal asthma broadly encompasses the presence of fungal sensitization or fungal allergy in patients with asthma. The clinical presentation of fungal asthma can vary from fungal-sensitized asthma at one end to allergic bronchopulmonary mycosis at the other end of the spectrum. Here we present five cases that illustrate some of the most challenging aspects of the diagnosis and management of fungal asthma. The cases are aimed at elucidating complex clinical presentations in fungal asthma such as allergic bronchopulmonary mycosis presenting with normal immunoglobulin E (IgE) values, the role of several different fungi in causing allergic mycosis, newer treatments like omalizumab (and mepolizumab), and a complication of long-standing allergic bronchopulmonary aspergillosis, namely, chronic pulmonary aspergillosis. CI - (c) The Author(s) 2019. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology. FAU - Agarwal, Ritesh AU - Agarwal R AD - Professor Department of Pulmonary Medicine Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. FAU - Sehgal, Inderpaul S AU - Sehgal IS AD - Assistant Professor. FAU - Dhooria, Sahajal AU - Dhooria S AD - Assistant Professor. FAU - Aggarwal, Ashutosh N AU - Aggarwal AN AD - Professor Department of Pulmonary Medicine Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. LA - eng PT - Journal Article PT - Review PL - England TA - Med Mycol JT - Medical mycology JID - 9815835 RN - 0 (Antifungal Agents) SB - IM MH - Antifungal Agents/therapeutic use MH - Asthma/diagnosis/*etiology MH - Diagnostic Tests, Routine/methods MH - *Disease Management MH - Humans MH - Lung Diseases, Fungal/*complications/diagnosis/drug therapy OTO - NOTNLM OT - Aspergillus OT - ABPA OT - ABPM OT - allergic bronchopulmonary aspergillosis OT - allergic bronchopulmonary mycosis OT - fungal sensitization EDAT- 2019/03/01 06:00 MHDA- 2019/03/26 06:00 CRDT- 2019/03/01 06:00 PHST- 2018/07/12 00:00 [accepted] PHST- 2018/04/27 00:00 [received] PHST- 2018/06/23 00:00 [revised] PHST- 2019/03/01 06:00 [entrez] PHST- 2019/03/01 06:00 [pubmed] PHST- 2019/03/26 06:00 [medline] AID - 5366903 [pii] AID - 10.1093/mmy/myy063 [doi] PST - ppublish SO - Med Mycol. 2019 Apr 1;57(Supplement_2):S110-S117. doi: 10.1093/mmy/myy063.