PMID- 30817626 OWN - NLM STAT- MEDLINE DCOM- 20190314 LR - 20210109 IS - 1536-5964 (Electronic) IS - 0025-7974 (Print) IS - 0025-7974 (Linking) VI - 98 IP - 9 DP - 2019 Mar TI - Meta-analysis of the effectiveness of laparoscopic adjustable gastric banding versus laparoscopic sleeve gastrectomy for obesity. PG - e14735 LID - 10.1097/MD.0000000000014735 [doi] LID - e14735 AB - BACKGROUND: Laparoscopic adjustable gastric banding (LAGB) and laparoscopic sleeve gastrectomy (LSG) are common weight loss procedures. Our meta-analysis compared these procedures for the treatment of morbid obesity and related diseases. METHODS: We systematically searched the PubMed, Embase, and the Cochrane Library through January 2018. The percentage of excess weight loss (%EWL), improvement or remission of type 2 diabetes mellitus (T2DM) and hypertension were analyzed and compared. RESULTS: Thirty-three studies with 4109 patients were included. Greater decreases in excess weight were found in patients who received LSG at 6 months (weighted mean difference (WMD) -9.29, 95% confidence interval (CI): -15.19 to -3.40, P = .002), 12 months (WMD -16.67 95% CI: -24.30 to -9.05, P < .0001), 24 months (WMD -19.63, 95% CI: -29.00 to -10.26, P < .0001), and 36 months (WMD -19.28, 95% CI: -27.09 to -11.47, P < .0001) than in patients who received LAGB. However, there were no significant differences in the 3-month outcomes between the 2 groups (WMD -1.61, 95% CI: -9.96 to 6.73, P = .70). T2DM patients after LSG experience more significant improvement or remission of diabetes (odds ratio (OR): 0.22, 95% CI: 0.06-0.87, P = .03). The 2 groups did not significantly differ regarding improvement or remission of hypertension (OR 0.80, 95% CI: 0.46-1.38, P = .42). CONCLUSION: LSG is a more effective procedure than LAGB for morbidly obese patients, contributing to a higher %EWL and greater improvement in T2DM. FAU - Li, Laiyuan AU - Li L AD - Department of Anorectal Surgery, Gansu Provincial Hospital. AD - Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Disease. FAU - Yu, Huichuan AU - Yu H AD - Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Disease. AD - Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University. FAU - Liang, Jinglin AU - Liang J AD - Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University. FAU - Guo, Yinyin AU - Guo Y AD - Department of Pharmacy, Lanzhou University Second Hospital. FAU - Peng, Shaoyong AU - Peng S AD - Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Disease. AD - Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University. FAU - Luo, Yanxin AU - Luo Y AD - Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Disease. AD - Department of Matabolic and Bariatric Surgery, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China. FAU - Wang, Jianping AU - Wang J AD - Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Disease. AD - Department of Matabolic and Bariatric Surgery, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China. LA - eng PT - Journal Article PT - Meta-Analysis PT - Review PL - United States TA - Medicine (Baltimore) JT - Medicine JID - 2985248R SB - IM MH - Body Mass Index MH - Diabetes Mellitus, Type 2/epidemiology/physiopathology MH - Gastrectomy/*methods MH - Gastroplasty/*methods MH - Humans MH - Hypertension/epidemiology/physiopathology MH - Laparoscopy/methods MH - Obesity, Morbid/epidemiology/*surgery MH - *Weight Loss PMC - PMC6831371 COIS- The authors have no conflicts of interest to disclose. EDAT- 2019/03/01 06:00 MHDA- 2019/03/15 06:00 PMCR- 2019/03/01 CRDT- 2019/03/01 06:00 PHST- 2019/03/01 06:00 [entrez] PHST- 2019/03/01 06:00 [pubmed] PHST- 2019/03/15 06:00 [medline] PHST- 2019/03/01 00:00 [pmc-release] AID - 00005792-201903010-00066 [pii] AID - MD-D-18-03087 [pii] AID - 10.1097/MD.0000000000014735 [doi] PST - ppublish SO - Medicine (Baltimore). 2019 Mar;98(9):e14735. doi: 10.1097/MD.0000000000014735.