PMID- 30820286 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220408 IS - 2008-2010 (Print) IS - 2008-322X (Electronic) IS - 2008-322X (Linking) VI - 14 IP - 1 DP - 2019 Jan-Mar TI - Analysis of Peripapillary Choroidal Thickness in Unilateral Amblyopia. PG - 42-47 LID - 10.4103/jovr.jovr_141_17 [doi] AB - PURPOSE: To evaluate the peripapillary choroidal thickness (CT) in children with unilateral amblyopia using spectral-domain optical coherence tomography (SD-OCT). METHODS: One hundred and six eyes of 53 children with unilateral amblyopia and 20 eyes of 20 children with normal vision were involved in this study. Of the 53 children with unilateral amblyopia, 29 (54.7%) had hyperopic anisometropic amblyopia and 24 (45.3%) had strabismic amblyopia. Peripapillary CT was measured from 6 mm length radial B-scans at the optic nerve head using the enhanced depth imaging program of an SD-OCT (Heidelberg Engineering, Germany). Age, sex, refractive error, and best-corrected visual acuity were also recorded. RESULTS: The average peripapillary CT was greater in amblyopic eyes than in the fellow eyes of the children with amblyopia (P = 0.002), and control eyes (P < 0.001). There was no significant difference between the fellow eyes of children with amblyopia and the control eyes (P = 0.158). The average peripapillary CT was negatively correlated with axial length (AL) in amblyopic eyes (r = -0.381; P = 0.005) and fellow eyes (r = -0.392; P = 0.004) but not in control eyes (r = -0.232; P = 0.325). After adjustment for the possible effects of AL, the average peripapillary CT in amblyopic eyes was still greater than in fellow eyes (P = 0.014) and control eyes (P = 0.022). CONCLUSION: The peripapillary choroid of eyes with amblyopia was thicker than that of the fellow eyes and control eyes. No significant difference was observed between fellow eyes and control eyes. FAU - Bitirgen, Gulfidan AU - Bitirgen G AUID- ORCID: 0000-0002-0509-5649 AD - Department of Ophthalmology, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Turkey. FAU - Mirza, Enver AU - Mirza E AUID- ORCID: 0000-0002-8847-5726 AD - Department of Ophthalmology, Konya Training and Research Hospital, Konya, Turkey. FAU - Ozkagnici, Ahmet AU - Ozkagnici A AUID- ORCID: 0000-0001-7411-2484 AD - Department of Ophthalmology, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Turkey. FAU - Iyisoy, Mehmet Sinan AU - Iyisoy MS AUID- ORCID: 0000-0001-5895-9984 AD - Department of Medical Education and Informatics, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Turkey. LA - eng PT - Journal Article PL - United Arab Emirates TA - J Ophthalmic Vis Res JT - Journal of ophthalmic & vision research JID - 101497643 PMC - PMC6388534 OTO - NOTNLM OT - Amblyopia OT - Anisometropia OT - Optical Coherence Tomography OT - Peripapillary Choroidal Thickness OT - Strabismus COIS- There are no conflicts of interest. EDAT- 2019/03/02 06:00 MHDA- 2019/03/02 06:01 PMCR- 2019/01/01 CRDT- 2019/03/02 06:00 PHST- 2019/03/02 06:00 [entrez] PHST- 2019/03/02 06:00 [pubmed] PHST- 2019/03/02 06:01 [medline] PHST- 2019/01/01 00:00 [pmc-release] AID - JOVR-14-42 [pii] AID - 10.4103/jovr.jovr_141_17 [doi] PST - ppublish SO - J Ophthalmic Vis Res. 2019 Jan-Mar;14(1):42-47. doi: 10.4103/jovr.jovr_141_17.