PMID- 30823939
OWN - NLM
STAT- MEDLINE
DCOM- 20200130
LR  - 20200130
IS  - 1944-7922 (Electronic)
IS  - 1060-3271 (Linking)
VI  - 102
IP  - 5
DP  - 2019 Sep 1
TI  - Determination of 11 Phthalate Esters in Beverages by Magnetic Solid-Phase 
      Extraction Combined with High-Performance Liquid Chromatography.
PG  - 1624-1631
LID - 10.5740/jaoacint.18-0316 [doi]
AB  - Background: Beverages can be easily contaminated by phthalate esters (PAEs) 
      during the production, bottling, and transportation processes. It is necessary to 
      determine the contamination level in beverages for assessment of human exposure. 
      Objective: In this study, magnetic solid-phase extraction (MSPE) was combined 
      with HPLC for the determination of 11 PAEs in beverages. Methods: 
      Self-synthesized magnetic multiwalled carbon nanotubes (m-MWCNTs) were used as 
      the adsorbent for PAE extraction. To extract the PAEs, an appropriate amount of 
      m-MWCNTs and NaCl was added to the beverage sample. The mixture was mixed on a 
      vortex mixer, the magnetic sorbent was collected with the aid of a magnet, and 
      the supernatant was removed. Then, the analytes were eluted with n-hexane-acetone 
      (1+1, v/v). Finally, the eluent was analyzed by the HPLC method. The separation 
      was accomplished on a Phenomenex Luna-C18 column (250 x 4.6 mm, 5 mum), and the 
      detection wavelength was set at 225 nm. Results: The linear ranges of the method 
      were 2-300 mug/L with correlation coefficients greater than 0.9981. The LOD and 
      LOQ were in the range of 0.659-5.33 x 10(-2) mug/L and 2.20-17.8 x 10(-2) mug/L, 
      respectively. The recoveries of the method ranged from 79.8 to 114%, with the 
      relative SDs less than 15.8%. The established method has been successfully 
      applied for the determination of 11 PAEs in mineral water, carbonated soft drink, 
      tea beverage, and fruit juice samples. PAEs were detected at 0.246-34.3 mug/L in 
      these samples. Conclusions: The m-MWCNTs are the satisfactory sorbent for MSPE 
      because of their strong adsorption capacity for PAEs. The established MSPE-HPLC 
      method is rapid, easy, sensitive, green, and cost-effective. It can be applied to 
      the analysis of trace PAEs in plastic bottled beverages. Highlights: Three 
      magnetic nanoparticles (MNPs), including Fe(3)O(4) MNPs, m-MWCNTs, and magnetic 
      graphene oxide, were synthesized, and m-MWCNTs were chosen as the sorbent of MSPE 
      for PAE extraction because of their strong adsorption capacity for PAEs. An 
      MSPE-HPLC method has been developed for the analysis of 11 phthalates in plastic 
      bottled beverages. The established method was successfully applied to the 
      analysis of 11 phthalates in four types of beverage samples.
FAU - Yin, Shuo
AU  - Yin S
AD  - Sichuan University, West China School of Public Health, Chengdu 610041, China.
FAU - Yang, Yi
AU  - Yang Y
AD  - Sichuan University, West China School of Public Health, Chengdu 610041, China.
FAU - Yang, Danni
AU  - Yang D
AD  - Sichuan University, West China School of Public Health, Chengdu 610041, China.
FAU - Li, Yongxin
AU  - Li Y
AD  - Sichuan University, West China School of Public Health, Chengdu 610041, China.
FAU - Jiang, Yang
AU  - Jiang Y
AD  - Sichuan Provincial Center for Disease Control and Prevention, Chengdu 610041, 
      China.
FAU - Wu, Ling
AU  - Wu L
AD  - Sichuan University, West China School of Public Health, Chengdu 610041, China.
FAU - Sun, Chengjun
AU  - Sun C
AD  - Sichuan University, West China School of Public Health, Chengdu 610041, China.
LA  - eng
PT  - Journal Article
DEP - 20190301
PL  - England
TA  - J AOAC Int
JT  - Journal of AOAC International
JID - 9215446
RN  - 0 (Drinking Water)
RN  - 0 (Esters)
RN  - 0 (Nanotubes, Carbon)
RN  - 0 (Phthalic Acids)
RN  - 0 (Tea)
SB  - IM
MH  - Adsorption
MH  - Beverages/*analysis
MH  - Carbonated Beverages/analysis
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Drinking Water/analysis
MH  - Esters/*analysis
MH  - Food Contamination/*analysis
MH  - Fruit and Vegetable Juices/analysis
MH  - Limit of Detection
MH  - Magnetic Phenomena
MH  - Nanotubes, Carbon/chemistry
MH  - Phthalic Acids/*analysis
MH  - Solid Phase Extraction/*methods
MH  - Tea/chemistry
EDAT- 2019/03/03 06:00
MHDA- 2020/01/31 06:00
CRDT- 2019/03/03 06:00
PHST- 2019/03/03 06:00 [pubmed]
PHST- 2020/01/31 06:00 [medline]
PHST- 2019/03/03 06:00 [entrez]
AID - 10.5740/jaoacint.18-0316 [doi]
PST - ppublish
SO  - J AOAC Int. 2019 Sep 1;102(5):1624-1631. doi: 10.5740/jaoacint.18-0316. Epub 2019 
      Mar 1.