PMID- 30824623
OWN - NLM
STAT- MEDLINE
DCOM- 20200527
LR  - 20200527
IS  - 1559-6095 (Electronic)
IS  - 1559-6095 (Linking)
VI  - 2019
IP  - 3
DP  - 2019 Mar 1
TI  - Transfected Dendritic Cell Immunizations.
LID - 10.1101/pdb.prot100073 [doi]
AB  - Dendritic cells (DCs) are the most potent antigen-presenting cells (APCs). An 
      efficient way of generating antibodies is to introduce antigens of interest into 
      DCs and then inject them into the host. This will result in initiation of an 
      antigen-specific immune response mediated by T-cell immunity. Apoptosis of DCs 
      expressing transgenic proteins results in enhanced immunity through 
      cross-presentation by endogenous DCs in vivo. The major advantage of this 
      technology is prolonged presentation of antigens that are synthesized 
      endogenously and their presentation by both modified DCs as well as endogenous 
      DCs to the immune system of the host.
CI  - (c) 2019 Cold Spring Harbor Laboratory Press.
FAU - Greenfield, Edward A
AU  - Greenfield EA
FAU - DeCaprio, James
AU  - DeCaprio J
FAU - Brahmandam, Mohan
AU  - Brahmandam M
LA  - eng
PT  - Journal Article
DEP - 20190301
PL  - United States
TA  - Cold Spring Harb Protoc
JT  - Cold Spring Harbor protocols
JID - 101524530
RN  - 0 (Antigens)
SB  - IM
MH  - Animals
MH  - Antigens/immunology
MH  - Apoptosis
MH  - Dendritic Cells/cytology/*immunology
MH  - Genetic Vectors
MH  - Lentivirus/genetics
MH  - Mice
MH  - *Transfection
EDAT- 2019/03/03 06:00
MHDA- 2020/05/28 06:00
CRDT- 2019/03/03 06:00
PHST- 2019/03/03 06:00 [entrez]
PHST- 2019/03/03 06:00 [pubmed]
PHST- 2020/05/28 06:00 [medline]
AID - 2019/3/pdb.prot100073 [pii]
AID - 10.1101/pdb.prot100073 [doi]
PST - epublish
SO  - Cold Spring Harb Protoc. 2019 Mar 1;2019(3). doi: 10.1101/pdb.prot100073.