PMID- 30826914 OWN - NLM STAT- MEDLINE DCOM- 20200415 LR - 20221207 IS - 1708-0428 (Electronic) IS - 0960-8923 (Linking) VI - 29 IP - 5 DP - 2019 May TI - Is Early Reimplantation of the Duodenal-Jejunal Bypass Liner Viable? PG - 1690-1693 LID - 10.1007/s11695-019-03758-y [doi] AB - The endoscopically implanted duodenal-jejunal bypass liner (DJBL) is an impermeable fluoropolymer device which prevents food making contact with the proximal intestine, thus inducing weight loss and improvement of type 2 diabetes mellitus (T2DM). However, weight and HbA1c levels generally increase post explantation. This study investigated the safety and feasibility of early DJBL reimplantation in five patients with obesity whose glucose levels had relapsed post explantation, examining the effect of reimplantation on weight loss, BMI and T2DM management. All DJBL implantation and explantation procedures were performed without complications. Despite reduction of T2DM medications, reduction in body weight and HbA1c levels resumed after reimplantation. In conclusion, early reimplantation of DJBL appears feasible, safe and effective. FAU - Leventi, Eleni AU - Leventi E AD - Department of Gastroenterology/Clinical Nutrition, DGD Clinics Sachsenhausen, Schulstrasse 31, Frankfurt am Main, Germany. AD - Obesity Centre, DGD Clinics Sachsenhausen, Frankfurt am Main, Germany. FAU - Gunthert, Sarah J AU - Gunthert SJ AD - Department of Gastroenterology/Clinical Nutrition, DGD Clinics Sachsenhausen, Schulstrasse 31, Frankfurt am Main, Germany. AD - Obesity Centre, DGD Clinics Sachsenhausen, Frankfurt am Main, Germany. FAU - Stier, Christine AU - Stier C AD - Department of General, Visceral, Cardiovascular and Pediatric Surgery, University Hospital, Wurzburg, Germany. FAU - Staikov, Plamen AU - Staikov P AD - Obesity Centre, DGD Clinics Sachsenhausen, Frankfurt am Main, Germany. AD - Department of General and Bariatric Surgery, DGD Clinics Sachsenhausen, Frankfurt am Main, Germany. FAU - Stein, Jurgen AU - Stein J AUID- ORCID: 0000-0003-3558-3341 AD - Department of Gastroenterology/Clinical Nutrition, DGD Clinics Sachsenhausen, Schulstrasse 31, Frankfurt am Main, Germany. J.Stein@em.uni-frankfurt.de. AD - Obesity Centre, DGD Clinics Sachsenhausen, Frankfurt am Main, Germany. J.Stein@em.uni-frankfurt.de. FAU - Farrag, Karima AU - Farrag K AD - Department of Gastroenterology/Clinical Nutrition, DGD Clinics Sachsenhausen, Schulstrasse 31, Frankfurt am Main, Germany. kfarrag@khs-ffm.de. AD - Obesity Centre, DGD Clinics Sachsenhausen, Frankfurt am Main, Germany. kfarrag@khs-ffm.de. LA - eng PT - Journal Article PT - Observational Study PL - United States TA - Obes Surg JT - Obesity surgery JID - 9106714 RN - 0 (Glycated Hemoglobin A) RN - 0 (hemoglobin A1c protein, human) SB - IM MH - Adult MH - Bariatric Surgery/*instrumentation MH - Body Mass Index MH - Device Removal MH - Diabetes Mellitus, Type 2/*surgery MH - Duodenum/*surgery MH - Endoscopy, Gastrointestinal MH - Feasibility Studies MH - Female MH - Glycated Hemoglobin/analysis MH - Humans MH - Jejunum/*surgery MH - Male MH - Middle Aged MH - Prostheses and Implants MH - *Reoperation MH - Retrospective Studies OTO - NOTNLM OT - Duodenal-jejunal bypass liner OT - Glycaemic control OT - Obesity OT - Obesity surgery OT - Type 2 diabetes OT - Weight loss EDAT- 2019/03/04 06:00 MHDA- 2020/04/16 06:00 CRDT- 2019/03/04 06:00 PHST- 2019/03/04 06:00 [pubmed] PHST- 2020/04/16 06:00 [medline] PHST- 2019/03/04 06:00 [entrez] AID - 10.1007/s11695-019-03758-y [pii] AID - 10.1007/s11695-019-03758-y [doi] PST - ppublish SO - Obes Surg. 2019 May;29(5):1690-1693. doi: 10.1007/s11695-019-03758-y.