PMID- 30830545 OWN - NLM STAT- MEDLINE DCOM- 20200318 LR - 20200318 IS - 1573-2630 (Electronic) IS - 0165-5701 (Linking) VI - 39 IP - 11 DP - 2019 Nov TI - Comparison of surgical parameters using different lens fragmentation patterns in eyes undergoing laser-assisted cataract surgery. PG - 2459-2465 LID - 10.1007/s10792-019-01087-8 [doi] AB - PURPOSE: To compare surgical parameters among eyes undergoing laser-assisted cataract surgery (LACS) using different lens fragmentation patterns (LFP). METHODS: Prospective, randomized, unmasked clinical trial. One-hundred eyes underwent LACS and were randomly assigned to 1 of 3 LFP treatment groups: (1) laser capsulotomy only; no lens fragmentation (NLF) (n = 34); (2) three-plane chop (TPC) (n = 33); and, (3) pie-cut pattern (PCP) fragmentation (n = 33). Prechop phacoemulsification (PHACO) was performed on all eyes using the same femtosecond (FS) laser and active-fluidics PHACO machine. MAIN OUTCOME MEASURES: FS laser dock time (s), PHACO time (s), PHACO power (%), cumulative dissipated energy (CDE) (%-s), irrigating fluid volume, and operative time. RESULTS: The 3 treatment groups were comparable in terms of patient age (P = 0.164) and nuclear density (P = 0.669). FS dock time was higher in the PCP group (184.18 +/- 25.86) compared to the TPC (145.09 +/- 14.15) group (P < 0.001). PHACO time was significantly shorter in the PCP (23.19 +/- 17.20 s) compared to TPC (35.27 +/- 17.70) and NLF (46.15 +/- 23.72) groups (P < 0.001). PHACO power was lower in the PCP (11.81 +/- 3.71) compared to the NLF (14.41 +/- 1.88) and TPC (14.04 +/- 2.46) groups (P < 0.001). CDE was lower in the PCP (2.85 +/- 2.32) compared to NLF (6.55 +/- 3.32) and TPC (6.55 +/- 5.45) groups (P < 0.001). Fluid volumes and operative times were similar. CONCLUSION: LFP can influence PHACO surgical parameters. Extensive fragmentation patterns such as PCP appear to lower PHACO time, power, and CDE and may potentially reduce the risk of PHACO related complications. FAU - Uy, Harvey S AU - Uy HS AD - Peregrine Eye and Laser Institute, 50 Jupiter Street, 1209, Makati City, Philippines. harveyuy@yahoo.com. AD - Department of Ophthalmology and Visual Sciences, University of the Philippines, Manila, Philippines. harveyuy@yahoo.com. FAU - Chan, Pik Sha AU - Chan PS AD - Peregrine Eye and Laser Institute, 50 Jupiter Street, 1209, Makati City, Philippines. FAU - Gil-Cazorla, Raquel AU - Gil-Cazorla R AD - Ophthalmic Research Group, Aston University, Birmingham, United Kingdom. FAU - Shah, Sunil AU - Shah S AD - Birmingham and Midland Eye Centre, Birmingham, UK. LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20190304 PL - Netherlands TA - Int Ophthalmol JT - International ophthalmology JID - 7904294 SB - IM MH - Aged MH - Cataract/*diagnosis MH - Densitometry/methods MH - Female MH - Follow-Up Studies MH - Humans MH - Imaging, Three-Dimensional MH - Laser Therapy/*methods MH - Lens, Crystalline/diagnostic imaging/*surgery MH - Male MH - Phacoemulsification/*methods MH - Postoperative Complications/prevention & control MH - Prospective Studies MH - Treatment Outcome MH - *Visual Acuity OTO - NOTNLM OT - LACS OT - Laser-assisted cataract surgery OT - Lens fragmentation OT - Phacoemulsification EDAT- 2019/03/05 06:00 MHDA- 2020/03/19 06:00 CRDT- 2019/03/05 06:00 PHST- 2018/04/16 00:00 [received] PHST- 2019/02/23 00:00 [accepted] PHST- 2019/03/05 06:00 [pubmed] PHST- 2020/03/19 06:00 [medline] PHST- 2019/03/05 06:00 [entrez] AID - 10.1007/s10792-019-01087-8 [pii] AID - 10.1007/s10792-019-01087-8 [doi] PST - ppublish SO - Int Ophthalmol. 2019 Nov;39(11):2459-2465. doi: 10.1007/s10792-019-01087-8. Epub 2019 Mar 4.