PMID- 30837247
OWN - NLM
STAT- MEDLINE
DCOM- 20200403
LR  - 20200403
IS  - 2044-6055 (Electronic)
IS  - 2044-6055 (Linking)
VI  - 9
IP  - 3
DP  - 2019 Mar 4
TI  - SOBRINA Spanish study-analysing the frequency, cost and adverse events associated 
      with overuse in primary care: protocol for a retrospective cohort study.
PG  - e023399
LID - 10.1136/bmjopen-2018-023399 [doi]
LID - e023399
AB  - INTRODUCTION: Several institutions and quality national agencies have fostered 
      the creation of recommendations on what not to do to reduce overuse in clinical 
      practice. In primary care, their impact has hardly been studied. The frequency of 
      adverse events (AEs) associated with doing what must not be done has not been 
      analysed, either. The aim of this study is to measure the frequency of overuse 
      and AEs associated with doing what must not be done (commission errors) in 
      primary care and their cost. METHODS AND ANALYSIS: A coordinated, multicentric, 
      national project. A retrospective cohort study using computerised databases of 
      primary care medical records from national agencies and regional health services 
      will be conducted to analyse the frequency of the overuse due to ignore the 
      do-not-do recommendations, and immediately afterwards, depending on their 
      frequency, a representative random sample of medical records will be reviewed 
      with algorithms (triggers) that determine the frequency of AEs associated with 
      these recommendations. Cost will determine by summation of the direct costs due 
      to the consultation, pharmacy, laboratory and imaging activities according to the 
      cases. ETHICS AND DISSEMINATION: The study protocol has been approved by the 
      Ethics Committee of Primary Care Research of the Valencian Community. We aim to 
      disseminate the findings through international peer-reviewed journals and on the 
      website (http://www.nohacer.es/). Outcomes will be used to incorporate algorithms 
      into the electronic history to assist in making clinical decisions. TRIAL 
      REGISTRATION NUMBER: NCT03482232; Pre-results.
CI  - (c) Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No 
      commercial re-use. See rights and permissions. Published by BMJ.
FAU - Mira, Jose Joaquin
AU  - Mira JJ
AD  - Department of Health Psychology, Universidad Miguel Hernandez de Elche, Elche, 
      Spain.
AD  - Salud Alicante-Sant Joan Health District, Alicante, Spain.
FAU - Carrillo, Irene
AU  - Carrillo I
AD  - Department of Health Psychology, Universidad Miguel Hernandez de Elche, Elche, 
      Spain.
FAU - Gea Velazquez de Castro, Maria Teresa
AU  - Gea Velazquez de Castro MT
AD  - Servicio de Medicina Preventiva y Calidad Asistencial, Hospital Universitari Sant 
      Joan d'Alacant, Sant Joan d'Alacant, Spain.
FAU - Silvestre, Carmen
AU  - Silvestre C
AD  - Servicio de Efectividad y Seguridad Asistencial, Servicio Navarro de Salud - 
      Osasunbidea, Pamplona, Spain.
FAU - Olivera, Guadalupe
AU  - Olivera G
AD  - Hospital Clinico San Carlos, Comunidad de Madrid Servicio Madrileno de Salud, 
      Madrid, Spain.
FAU - Caro-Mendivelso, Johanna
AU  - Caro-Mendivelso J
AD  - Agency for Health Quality and Assessment of Catalonia (AQuAS), Barcelona, Spain.
FAU - Perez-Perez, Pastora
AU  - Perez-Perez P
AD  - Patient Safety Observatory, AndalusianAgency for Health Care Quality, Seville, 
      Spain.
FAU - Agra, Yolanda
AU  - Agra Y
AD  - Area de Seguridad del Paciente, Ministerio de Sanidad Servicios Sociales e 
      Igualdad, Madrid, Spain.
FAU - Fernandez, Ana M feminine
AU  - Fernandez AM
AD  - Servicio de Efectividad y Seguridad Asistencial, Servicio Navarro de Salud - 
      Osasunbidea, Pamplona, Spain.
FAU - Aranaz-Andres, Jesus Maria
AU  - Aranaz-Andres JM
AD  - Preventive Medicine and Public Health, Hospital Universitario Ramon y Cajal, 
      Madrid, Spain.
AD  - Instituto Ramon y Cajal de Investigacion Sanitaria, IRYCIS, Madrid, Spain.
CN  - SOBRINA Research Team
LA  - eng
SI  - ClinicalTrials.gov/NCT03482232
PT  - Journal Article
PT  - Multicenter Study
PT  - Observational Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20190304
PL  - England
TA  - BMJ Open
JT  - BMJ open
JID - 101552874
SB  - IM
MH  - *Costs and Cost Analysis
MH  - Electronic Health Records
MH  - Health Care Costs
MH  - Humans
MH  - Medical Errors/*adverse effects
MH  - Medical Overuse/*economics/*statistics & numerical data
MH  - Primary Health Care/*economics
MH  - Research Design
MH  - Retrospective Studies
MH  - Spain
PMC - PMC6429720
OTO - NOTNLM
OT  - overuse
OT  - patient safety
OT  - primary care
OT  - quality assurance
OT  - scientific societies
COIS- Competing interests: None declared.
FIR - Ariztegui, Ana Maria
IR  - Ariztegui AM
FIR - Astier, Maria Pilar
IR  - Astier MP
FIR - Carratala, Maria Concepcion
IR  - Carratala MC
FIR - Cebrian, Ana Maria
IR  - Cebrian AM
FIR - Gonzalez, Javier
IR  - Gonzalez J
FIR - Nebot, Cristina M feminine
IR  - Nebot CM
FIR - Nuin, M feminine Angeles
IR  - Nuin MA
FIR - Rincon, Angela
IR  - Rincon A
FIR - Ruiz, Jose Maria
IR  - Ruiz JM
FIR - Torijano, Maria Luisa
IR  - Torijano ML
FIR - Vitaller, Julian
IR  - Vitaller J
FIR - Zavala, Elena
IR  - Zavala E
EDAT- 2019/03/07 06:00
MHDA- 2020/04/04 06:00
PMCR- 2019/03/04
CRDT- 2019/03/07 06:00
PHST- 2019/03/07 06:00 [entrez]
PHST- 2019/03/07 06:00 [pubmed]
PHST- 2020/04/04 06:00 [medline]
PHST- 2019/03/04 00:00 [pmc-release]
AID - bmjopen-2018-023399 [pii]
AID - 10.1136/bmjopen-2018-023399 [doi]
PST - epublish
SO  - BMJ Open. 2019 Mar 4;9(3):e023399. doi: 10.1136/bmjopen-2018-023399.