PMID- 30843437 OWN - NLM STAT- MEDLINE DCOM- 20210624 LR - 20210624 IS - 1532-7027 (Electronic) IS - 1041-0236 (Linking) VI - 35 IP - 6 DP - 2020 May TI - A Stress Buffering Perspective on the Progression of Alpha-1 Antitrypsin Deficiency. PG - 747-755 LID - 10.1080/10410236.2019.1584782 [doi] AB - This study used the stress buffering perspective to identify social resources, including social network support, having a high quality marriage, and spousal support, that protect against deleterious effects of the progression of Alpha-1 antitrypsin deficiency (AATD) on quality of life. Participants included 130 married adults living with AATD. We measured participants' quality of life in three ways: perceived stress, life satisfaction, and perceptions of social stigma. The results suggested that disease progression corresponded positively with perceived stress and negatively with life satisfaction. Social network support moderated the association between disease progression and perceived stress and social stigma, and spousal support moderated the association between disease progression and perceived stress and life satisfaction. Marital quality was not a significant moderator. The discussion highlights the stress buffering effects of social support from close others. FAU - Tian, Xi AU - Tian X AD - Department of Communication Arts and Sciences, The Pennsylvania State University. FAU - Solomon, Denise Haunani AU - Solomon DH AD - Department of Communication Arts and Sciences, The Pennsylvania State University. FAU - Smith, Rachel A AU - Smith RA AUID- ORCID: 0000-0003-2407-7515 AD - Department of Communication Arts and Sciences, The Pennsylvania State University. LA - eng GR - R21 HG007111/HG/NHGRI NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural DEP - 20190307 PL - England TA - Health Commun JT - Health communication JID - 8908762 SB - IM MH - Adult MH - Humans MH - Marriage MH - *Quality of Life MH - Social Stigma MH - Social Support MH - Stress, Psychological MH - *alpha 1-Antitrypsin Deficiency EDAT- 2019/03/08 06:00 MHDA- 2021/06/25 06:00 CRDT- 2019/03/08 06:00 PHST- 2019/03/08 06:00 [pubmed] PHST- 2021/06/25 06:00 [medline] PHST- 2019/03/08 06:00 [entrez] AID - 10.1080/10410236.2019.1584782 [doi] PST - ppublish SO - Health Commun. 2020 May;35(6):747-755. doi: 10.1080/10410236.2019.1584782. Epub 2019 Mar 7.