PMID- 30854005
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220408
IS  - 1741-427X (Print)
IS  - 1741-4288 (Electronic)
IS  - 1741-427X (Linking)
VI  - 2019
DP  - 2019
TI  - Study on the Differences between Traditional Chinese Medicine Syndromes in NYHA 
      I-IV Classification of Chronic Heart Failure.
PG  - 2543413
LID - 10.1155/2019/2543413 [doi]
LID - 2543413
AB  - OBJECTIVES: This study investigated the distribution of characteristics of 
      traditional Chinese medicine syndromes and their association with symptoms in 
      1027 patients with chronic heart failure (CHF). METHODS: An observational study 
      was performed by researchers, collecting data from 1036 patients with CHF from 24 
      Chinese medicine hospitals from May 2009 to December 2014. Due to incomplete 
      information from nine patients, 1027 patients with CHF were analysed. The 
      distribution of syndromes in CHF and association between high-frequency syndromes 
      and symptoms were investigated. RESULTS: The primary syndromes were qi 
      deficiency, blood stasis, fluid retention, yin deficiency, phlegm turbidity, and 
      yang deficiency. The primary sites of disease were the heart, kidney, lung, and 
      spleen. In patients with CHF of differing cardiac function, there was no 
      significant difference in the frequency of yin deficiency (P>0.05). The 
      distribution of yang deficiency was significantly different between New York Heat 
      Association (NYHA) classes II, III, and IV and between classes I+II and III+IV 
      (P<0.05). The frequency of phlegm turbidity was significantly different between 
      NYHA classes II and III, between classes III and IV, and between classes I+II and 
      III+IV (P<0.05). The frequency of fluid retention was significantly different 
      between NYHA classes I and IV, between classes II, III, and IV, and between 
      classes I+II and III+IV (P<0.05). Regarding associations between syndromes and 
      symptoms, qi deficiency was diagnosed in 87.43% of patients with insomnia and 
      spiritlessness; blood stasis in 84.85% of patients with spontaneous sweating + 
      cyanosis of the lips; fluid retention in 75% of patients with a hard pulse and 
      oedema; and yin deficiency in 72.92% of patients with feverish sensation in the 
      chest, palms, and soles and spontaneous sweating. CONCLUSIONS: The frequency of 
      yang deficiency and fluid retention was higher and that of phlegm turbidity was 
      lower in classes III and IV than in classes I and II.
FAU - Shi, Jun
AU  - Shi J
AD  - Beijing University of Chinese Medicine (Institute of Traditional Chinese 
      Medicine; Beijing Key Laboratory of TCM Syndrome and Formula; Ministry of 
      Education Key Laboratory of TCM Syndrome and Formula), Bei San Huan Dong Lu, Chao 
      Yang District, Beijing 100029, China.
AD  - Basic Medical School of Inner Mongolia Medical University, Hohhot 010010, China.
FAU - Luo, Liangtao
AU  - Luo L
AD  - Beijing University of Chinese Medicine (Institute of Traditional Chinese 
      Medicine; Beijing Key Laboratory of TCM Syndrome and Formula; Ministry of 
      Education Key Laboratory of TCM Syndrome and Formula), Bei San Huan Dong Lu, Chao 
      Yang District, Beijing 100029, China.
FAU - Chen, Jing
AU  - Chen J
AD  - Beijing University of Chinese Medicine (Institute of Traditional Chinese 
      Medicine; Beijing Key Laboratory of TCM Syndrome and Formula; Ministry of 
      Education Key Laboratory of TCM Syndrome and Formula), Bei San Huan Dong Lu, Chao 
      Yang District, Beijing 100029, China.
FAU - Wang, Juan
AU  - Wang J
AD  - Beijing University of Chinese Medicine (Institute of Traditional Chinese 
      Medicine; Beijing Key Laboratory of TCM Syndrome and Formula; Ministry of 
      Education Key Laboratory of TCM Syndrome and Formula), Bei San Huan Dong Lu, Chao 
      Yang District, Beijing 100029, China.
FAU - Zhao, Huihui
AU  - Zhao H
AUID- ORCID: 0000-0002-3936-777X
AD  - Beijing University of Chinese Medicine (Institute of Traditional Chinese 
      Medicine; Beijing Key Laboratory of TCM Syndrome and Formula; Ministry of 
      Education Key Laboratory of TCM Syndrome and Formula), Bei San Huan Dong Lu, Chao 
      Yang District, Beijing 100029, China.
FAU - Wang, Wei
AU  - Wang W
AUID- ORCID: 0000-0001-5401-3331
AD  - Beijing University of Chinese Medicine (Institute of Traditional Chinese 
      Medicine; Beijing Key Laboratory of TCM Syndrome and Formula; Ministry of 
      Education Key Laboratory of TCM Syndrome and Formula), Bei San Huan Dong Lu, Chao 
      Yang District, Beijing 100029, China.
LA  - eng
PT  - Journal Article
DEP - 20190203
PL  - United States
TA  - Evid Based Complement Alternat Med
JT  - Evidence-based complementary and alternative medicine : eCAM
JID - 101215021
PMC - PMC6378041
EDAT- 2019/03/12 06:00
MHDA- 2019/03/12 06:01
PMCR- 2019/02/03
CRDT- 2019/03/12 06:00
PHST- 2018/10/04 00:00 [received]
PHST- 2018/11/28 00:00 [revised]
PHST- 2019/01/02 00:00 [accepted]
PHST- 2019/03/12 06:00 [entrez]
PHST- 2019/03/12 06:00 [pubmed]
PHST- 2019/03/12 06:01 [medline]
PHST- 2019/02/03 00:00 [pmc-release]
AID - 10.1155/2019/2543413 [doi]
PST - epublish
SO  - Evid Based Complement Alternat Med. 2019 Feb 3;2019:2543413. doi: 
      10.1155/2019/2543413. eCollection 2019.