PMID- 30862267
OWN - NLM
STAT- MEDLINE
DCOM- 20190606
LR  - 20190606
IS  - 1944-0057 (Electronic)
IS  - 1944-0057 (Linking)
VI  - 36
IP  - 4
DP  - 2019 Apr
TI  - Persistent organic pollutants in fish: biomonitoring and cocktail effect with 
      implications for food safety.
PG  - 601-611
LID - 10.1080/19440049.2019.1579926 [doi]
AB  - The impact of anthropogenic wastes of persistent organic pollutants (POPs) on the 
      marine environment has increased in the last decades. POPs include 
      polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCs). To assess 
      the levels of these POPs in the wild fish population, pelagic and benthopelagic 
      predator fish species were selected as biomonitors. For detection and 
      quantification of POPs in muscular tissues, a simple extraction through 
      Accelerated-Solvent-Extraction (ASE) with an 'in-line' clean up purification 
      approach was applied, followed by a GC-MS/MS analysis. Concentrations of sum DDT, 
      sum HCH and endrin correlated with all PCB concentrations. Significant 
      differences among fish species were found for all OCs and all PCBs except PCB 31 
      and 101. Blackspot seabream had the highest PCB concentrations; OCs were highest 
      in tuna. Due to major concerns regarding fish population losses and the possible 
      human chronic exposure to contaminated fish, studies addressing combined effects 
      of multiple POPs ('cocktail effect') should be implemented. Our data motivate 
      further experimental and observational studies in fish to define adequate 
      baseline levels for cumulative human exposure and potential role of these 
      contaminants for food safety.
FAU - Panseri, Sara
AU  - Panseri S
AD  - a Department of Health , Animal Science and Food Safety, University of Milan , 
      Milan , Italy.
FAU - Chiesa, Luca
AU  - Chiesa L
AD  - a Department of Health , Animal Science and Food Safety, University of Milan , 
      Milan , Italy.
FAU - Ghisleni, Gabriele
AU  - Ghisleni G
AD  - b DIMEVET-Department of Veterinary Medicine , School of Veterinary Medicine , 
      Milano , Italy.
FAU - Marano, Giuseppe
AU  - Marano G
AD  - c Department of Clinical Sciences and Community Health Laboratory of Medical 
      Statistics, Epidemiology and Biometry G. A. Maccacaro , University of Milan , 
      Milan , Italy.
FAU - Boracchi, Patrizia
AU  - Boracchi P
AD  - d Unit of Medical Statistics, Biometry and Bioinformatics , Fondazione IRCSS 
      Istituto Nazionale Tumori di Milano , Milan , Italy.
FAU - Ranghieri, Valerio
AU  - Ranghieri V
AD  - e Veterinary Food Safety Consultants, Fish Market , Milan , Italy.
FAU - Malandra, Renato M
AU  - Malandra RM
AD  - f National Health Service , ATS Veterinary Service , Milano , MI , Italy.
FAU - Roccabianca, Paola
AU  - Roccabianca P
AD  - b DIMEVET-Department of Veterinary Medicine , School of Veterinary Medicine , 
      Milano , Italy.
FAU - Tecilla, Marco
AU  - Tecilla M
AD  - b DIMEVET-Department of Veterinary Medicine , School of Veterinary Medicine , 
      Milano , Italy.
LA  - eng
PT  - Journal Article
DEP - 20190312
PL  - England
TA  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess
JT  - Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & 
      risk assessment
JID - 101485040
RN  - 0 (Environmental Pollutants)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Pesticides)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Animals
MH  - *Environmental Monitoring
MH  - Environmental Pollutants/*analysis
MH  - Fishes
MH  - Food Analysis
MH  - Food Contamination/*analysis
MH  - *Food Safety
MH  - Humans
MH  - Hydrocarbons, Chlorinated/*analysis
MH  - Pesticides/*analysis
MH  - Polychlorinated Biphenyls/*analysis
OTO - NOTNLM
OT  - Fish
OT  - chronic toxicity
OT  - environmental monitoring
OT  - food safety
OT  - organochlorine pesticides (OCs)
OT  - persistent organic pollutants (POPs)
OT  - polychlorinated biphenyls (PCBs)
EDAT- 2019/03/14 06:00
MHDA- 2019/06/07 06:00
CRDT- 2019/03/14 06:00
PHST- 2019/03/14 06:00 [pubmed]
PHST- 2019/06/07 06:00 [medline]
PHST- 2019/03/14 06:00 [entrez]
AID - 10.1080/19440049.2019.1579926 [doi]
PST - ppublish
SO  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2019 
      Apr;36(4):601-611. doi: 10.1080/19440049.2019.1579926. Epub 2019 Mar 12.