PMID- 30863550
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2053-8855 (Print)
IS  - 2053-8855 (Electronic)
IS  - 2053-8855 (Linking)
VI  - 2019
IP  - 2
DP  - 2019 Feb
TI  - A case of metastatic adrenocortical carcinoma.
PG  - omz006
LID - 10.1093/omcr/omz006 [doi]
LID - omz006
AB  - Adrenocortical carcinoma is a rare endocrine malignancy with poor prognosis. 
      Adrenocortical carcinoma can be seen in familial syndromes such as multiple 
      endocrine neoplasia 1(MEN-1), Li-Fraumeni syndrome, Beckwith-Wiedemann syndrome 
      and Carney complex (Kjellman, M, Roshani, L, The, BT et al. Genotyping of 
      adrenocortical tumours: very frequent deletions of the MEN1 locus in 11q13 and of 
      a 1-centimorgan region in 2p16. J Clin Endocrinol Metab 1999;84:730-5). Treatment 
      options for adrenocortical carcinoma are limited. We report a case of 
      adrenocortical carcinoma in a 50-year-old lady who subsequently underwent 
      adrenalectomy. She was started on mitotane as adjuvant therapy and chemotherapy 
      after the metastatic lesions were found. Due to the rarity of the tumour, the 
      understanding and experience of management modalities is limited. New treatment 
      options may be available in the coming years to improve outcome. Early 
      identification of tumour is key to increase the chances of progression free 
      survival.
FAU - Kuthiah, N
AU  - Kuthiah N
AD  - General Medicine, Alexandra Health System Woodlands Health Campus, Singapore.
FAU - Er, C
AU  - Er C
AUID- ORCID: 0000-0001-9753-6271
AD  - General Medicine, Alexandra Health System Woodlands Health Campus, Singapore.
LA  - eng
PT  - Case Reports
DEP - 20190227
PL  - England
TA  - Oxf Med Case Reports
JT  - Oxford medical case reports
JID - 101642070
PMC - PMC6402308
EDAT- 2019/03/14 06:00
MHDA- 2019/03/14 06:01
PMCR- 2019/02/27
CRDT- 2019/03/14 06:00
PHST- 2018/09/06 00:00 [received]
PHST- 2018/12/03 00:00 [revised]
PHST- 2019/01/22 00:00 [accepted]
PHST- 2019/03/14 06:00 [entrez]
PHST- 2019/03/14 06:00 [pubmed]
PHST- 2019/03/14 06:01 [medline]
PHST- 2019/02/27 00:00 [pmc-release]
AID - omz006 [pii]
AID - 10.1093/omcr/omz006 [doi]
PST - epublish
SO  - Oxf Med Case Reports. 2019 Feb 27;2019(2):omz006. doi: 10.1093/omcr/omz006. 
      eCollection 2019 Feb.