PMID- 30865346
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 1941-2452 (Electronic)
IS  - 0884-5336 (Linking)
VI  - 32
IP  - 1
DP  - 2017 Feb
TI  - Sarcopenia Is Highly Prevalent in Older Medical Patients With Mobility 
      Limitation: Comparisons According to Ambulatory Status.
PG  - 110-115
LID - 10.1177/0884533616680355 [doi]
AB  - BACKGROUND: The association of sarcopenia with disability with ambulatory status 
      is uncertain because most studies have targeted people who could walk 
      independently. This study explored the prevalence of sarcopenia regardless of 
      ambulatory status and the impact of ambulatory status on sarcopenia. MATERIALS 
      AND METHODS: In total, 778 consecutive patients, aged >/=65 years and admitted to a 
      hospital, were enrolled. Ambulatory status was divided into 4 grades according to 
      mobility as described in the Barthel index. Sarcopenia was defined as a loss of 
      appendicular muscle mass index (AMI) with bioelectrical impedance and decreased 
      muscle strength with handgrip strength (HGS); cutoff values were adopted from the 
      Asian Working Group for Sarcopenia. RESULTS: The mean patient age was 83.2 +/- 8.3 
      years; 37.8% were male patients. Mobility limitation was associated with higher 
      age, underweight body mass index, malnourishment, and comorbidities (all P < 
      .001). AMI and HGS gradually decreased with declining ambulatory status (P < 
      .001). The prevalence of sarcopenia in the independent walk, walk with help, 
      wheelchair, and immobile groups was 57.9%, 76.1%, 89.4%, and 91.7%, respectively. 
      AMI prevalence declined and sarcopenia drastically increased in patients who were 
      unable to walk independently compared with those who could walk independently (P 
      < .001). Multivariate regression analyses showed that mobility limitation was an 
      independent indicator of decreasing AMI and sarcopenia after adjustment for 
      confounders. CONCLUSION: Patients with dependent ambulatory status experienced a 
      higher prevalence of sarcopenia compared with those with ambulation; in addition, 
      decline in ambulatory status was an independent indicator for the presence of 
      sarcopenia after adjustment for potential confounders.
CI  - (c) 2017 by The American Society for Parenteral and Enteral Nutrition.
FAU - Maeda, Keisuke
AU  - Maeda K
AD  - Department of Nutrition and Dysphagia Rehabilitation, Tamana Regional Health 
      Medical Center, Kumamoto, Japan.
FAU - Shamoto, Hiroshi
AU  - Shamoto H
AD  - Department of Neurosurgery, Minamisoma Municipal General Hospital, Fukushima, 
      Japan.
FAU - Wakabayashi, Hidetaka
AU  - Wakabayashi H
AD  - Department of Rehabilitation Medicine, Yokohama City University Medical Center, 
      Yokohama, Japan.
FAU - Akagi, Junji
AU  - Akagi J
AD  - Department of Surgery, Tamana Regional Health Medical Center, Kumamoto, Japan.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Nutr Clin Pract
JT  - Nutrition in clinical practice : official publication of the American Society for 
      Parenteral and Enteral Nutrition
JID - 8606733
OTO - NOTNLM
OT  - Barthel index
OT  - ambulation
OT  - frail elderly
OT  - mobility limitation
OT  - older adults
OT  - sarcopenia
OT  - skeletal muscle mass
EDAT- 2017/02/01 00:00
MHDA- 2017/02/01 00:01
CRDT- 2019/03/14 06:00
PHST- 2019/03/14 06:00 [entrez]
PHST- 2017/02/01 00:00 [pubmed]
PHST- 2017/02/01 00:01 [medline]
AID - 10.1177/0884533616680355 [doi]
PST - ppublish
SO  - Nutr Clin Pract. 2017 Feb;32(1):110-115. doi: 10.1177/0884533616680355.