PMID- 30866679 OWN - NLM STAT- MEDLINE DCOM- 20200707 LR - 20210502 IS - 1873-1953 (Electronic) IS - 1474-5151 (Print) IS - 1474-5151 (Linking) VI - 18 IP - 5 DP - 2019 Jun TI - The relationship between physical activity and appetite in patients with heart failure: A prospective observational study. PG - 410-417 LID - 10.1177/1474515119836567 [doi] AB - INTRODUCTION: Physical activity and appetite are important components for maintaining health. Yet, the association between physical activity and appetite in heart failure (HF) populations is not completely understood. The aim of the present study was to investigate the relationship between physical activity, functional capacity, and appetite in patients with HF. METHODS: This was a prospective observational study. In total, 186 patients diagnosed with HF, New York Heart Association (NYHA) class II-IV (mean age 70.7, 30% female), were included. Physical activity was measured using a multi-sensor actigraph for seven days and with a self-reported numeric rating scale. Physical capacity was measured by the six-minute walk test. Appetite was measured using the Council on Nutrition Appetite Questionnaire. Data were collected at inclusion and after 18 months. A series of linear regression analyses, adjusted for age, NYHA class, and B-type natriuretic peptide were conducted. RESULTS: At baseline, higher levels of physical activity and functional capacity were significantly associated with a higher level of appetite in the unadjusted models. In the adjusted models, number of steps ( p = 0.019) and the six-minute walk test ( p = 0.007) remained significant. At the 18-month follow-up, all physical activity variables and functional capacity were significantly associated with appetite in the unadjusted regression models. In the adjusted models, number of steps ( p = 0.001) and metabolic equivalent daily averages ( p = 0.040) remained significant. CONCLUSION: A higher level of physical activity measured by number of steps/day was associated with better self-reported appetite, both at baseline and the 18-month follow-up. Further research is needed to establish causality and explore the intertwined relationship between activity and appetite in patients with HF. FAU - Andreae, Christina AU - Andreae C AD - 1 Department of Medical and Health Sciences, Division of Nursing Science, Linkoping University, Sweden. AD - 2 Centre for Clinical Research Sormland, Uppsala University, Eskilstuna, Sweden. FAU - Arestedt, Kristofer AU - Arestedt K AD - 3 Faculty of Health and Life Sciences, Linnaeus University, Kalmar, Sweden. AD - 4 The Research Section, Region Kalmar County, Sweden. FAU - Evangelista, Lorraine AU - Evangelista L AD - 5 Sue and Bill Gross School of Nursing, University of California, Irvine, USA. FAU - Stromberg, Anna AU - Stromberg A AD - 1 Department of Medical and Health Sciences, Division of Nursing Science, Linkoping University, Sweden. AD - 5 Sue and Bill Gross School of Nursing, University of California, Irvine, USA. AD - 6 Department of Cardiology, Linkoping University, Sweden. LA - eng GR - R01 HL093466/HL/NHLBI NIH HHS/United States GR - R21 AG053162/AG/NIA NIH HHS/United States PT - Journal Article PT - Observational Study PT - Research Support, Non-U.S. Gov't DEP - 20190313 PL - England TA - Eur J Cardiovasc Nurs JT - European journal of cardiovascular nursing JID - 101128793 SB - IM MH - Aged MH - Exercise/*physiology/*psychology MH - Exercise Tolerance/*physiology MH - Feeding and Eating Disorders/*etiology MH - Female MH - Heart Failure/*complications MH - Humans MH - Male MH - Middle Aged MH - Prospective Studies MH - Self Report MH - Surveys and Questionnaires PMC - PMC8087199 MID - NIHMS1696326 OTO - NOTNLM OT - Appetite OT - heart failure OT - physical activity COIS- Declaration of conflicting interests None declared. EDAT- 2019/03/15 06:00 MHDA- 2020/07/08 06:00 PMCR- 2021/04/30 CRDT- 2019/03/15 06:00 PHST- 2019/03/15 06:00 [pubmed] PHST- 2020/07/08 06:00 [medline] PHST- 2019/03/15 06:00 [entrez] PHST- 2021/04/30 00:00 [pmc-release] AID - 10.1177/1474515119836567 [doi] PST - ppublish SO - Eur J Cardiovasc Nurs. 2019 Jun;18(5):410-417. doi: 10.1177/1474515119836567. Epub 2019 Mar 13.