PMID- 30867644
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220408
IS  - 1452-8258 (Print)
IS  - 1452-8266 (Electronic)
IS  - 1452-8266 (Linking)
VI  - 38
IP  - 2
DP  - 2019 Apr
TI  - Relationship Between Hematological Parameters and Glycemic Control in Type 2 
      Diabetes Mellitus Patients.
PG  - 164-171
LID - 10.2478/jomb-2018-0021 [doi]
AB  - BACKGROUND: Diabetes mellitus (DM) with its micro- and macrocomplications is the 
      leading global epidemic of the 21st century. The aim of the research is to 
      determine possible changes in the complete blood count (CBC) parameters depending 
      on glycemic controlin patients with Type 2 diabetes mellitus (T2DM). METHODS: The 
      study included a total of 178 patients with T2DM, both gender over the age of 40 
      years, from the Health Care Center >>Dr Milorad Mika Pavlovic<< Indjija, Serbia. To 
      notice the possible correlation between the CBC parameters and glucose control in 
      T2DM, the subjects were divided in two groups with HbA1c </= 7% and with HbA1c>7%. 
      We analysed CBC parameters, parameters of glycoregulation, lipid status using 
      standard biochemical methods, performed anthropometric measurements and collected 
      patients data by questionnaire and electronic patient card. RESULTS: There was 
      statistical difference between HbA1c groups for PMDW (p=0.045), HDL (p=0.0067). 
      Using univariate linear regression it is shown that PCT was correlated with WBC 
      (p=0.0005), neutrophils (p=0.046), monocytes (p=0.003); MPM was associated with 
      MPV (p=0.0005); MPC (p=0.0005), PDW (P=0.0005), GLU0 (p=0.034), HDL-C (p=0.005); 
      PMDW was correlated with HbA1c% (p=0.049), GLU0 (p=0.013), HDL-C (p=0.001), BW 
      (p=0.043) in all patients. CONCLUSIONS: Based on our study results it may be 
      concluded that some of the parameters of CBC could be useful tool in following 
      glycemic control of diabetics.
FAU - Milosevic, Dragana
AU  - Milosevic D
AD  - Department of Laboratory Diagnostics, Health Care Center >>Dr Milorad Mika 
      Pavlovic<<, Indjija, Serbia.
AD  - Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
FAU - Panin, Violeta Lukic
AU  - Panin VL
AD  - Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
LA  - eng
PT  - Journal Article
DEP - 20190303
PL  - Serbia
TA  - J Med Biochem
JT  - Journal of medical biochemistry
JID - 101315490
PMC - PMC6410995
OTO - NOTNLM
OT  - CBC parameters
OT  - HbA1c
OT  - T2DM
OT  - platelets
COIS- Conflict of interest Conflict of interest statement: The authors state that they 
      have no conflicts of interest regarding the publication of this article.
EDAT- 2019/03/15 06:00
MHDA- 2019/03/15 06:01
PMCR- 2019/03/03
CRDT- 2019/03/15 06:00
PHST- 2018/04/04 00:00 [received]
PHST- 2018/07/04 00:00 [accepted]
PHST- 2019/03/15 06:00 [entrez]
PHST- 2019/03/15 06:00 [pubmed]
PHST- 2019/03/15 06:01 [medline]
PHST- 2019/03/03 00:00 [pmc-release]
AID - jomb-2018-0021 [pii]
AID - 10.2478/jomb-2018-0021 [doi]
PST - epublish
SO  - J Med Biochem. 2019 Mar 3;38(2):164-171. doi: 10.2478/jomb-2018-0021. eCollection 
      2019 Apr.