PMID- 30882660 OWN - NLM STAT- MEDLINE DCOM- 20190403 LR - 20221005 IS - 1536-5964 (Electronic) IS - 0025-7974 (Print) IS - 0025-7974 (Linking) VI - 98 IP - 11 DP - 2019 Mar TI - Effectiveness of neuromuscular electrical stimulation and ibuprofen for pain caused by necrosis of the femoral head: A retrospective study. PG - e14812 LID - 10.1097/MD.0000000000014812 [doi] LID - e14812 AB - This retrospective study analyzed the effectiveness of neuromuscular electrical stimulation (NMES) for pain relief caused by necrosis of femoral head (NFH).Totally, 80 cases of patients with NFH were analyzed and then were assigned to a treatment group or a control group in this study. Of these, 40 cases in the treatment group received ibuprofen and NMES therapy. The other 40 cases in the control group received ibuprofen alone. Cases in both groups were treated for a total of 6 weeks. The primary outcome of pain intensity was measured by a visual analog scale (VAS). The secondary outcome was assessed by Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). In addition, adverse events (AEs) were also recorded in each case. All outcomes were evaluated before and after the treatment.After treatment, patients in the treatment group showed more effectiveness in pain relief, as measured by VAS (P < .01) and WOMAC sub-pain scale (P < .01), except stiffness, as evaluated by WOMAC sub-stiffness scale (P = .07), and function, as assessed by WOMAC sub-function scale (P = .09), than patients in the control group. Additionally, no significant differences in AEs were detected between 2 groups.This study found that NMES may be helpful for pain relief in patients with NFH. FAU - Ji, Qing-Hui AU - Ji QH AD - First Ward of Orthopedics Department, First Affiliated Hospital of Jiamusi University. FAU - Qiao, Xiao-Feng AU - Qiao XF AD - First Ward of Orthopedics Department, First Affiliated Hospital of Jiamusi University. FAU - Wang, Shou-Feng AU - Wang SF AD - First Ward of Orthopedics Department, First Affiliated Hospital of Jiamusi University. FAU - Zhao, Peng AU - Zhao P AD - Department of Orthopedics, Jiamusi Central Hospital. FAU - Liu, Shi-Chen AU - Liu SC AD - First Ward of Orthopedics Department, First Affiliated Hospital of Jiamusi University. FAU - Xue, Yu AU - Xue Y AD - Department of Surgery, Second Affiliated Hospital of Jiamusi University, Jiamusi. FAU - Qiao, Jian-Min AU - Qiao JM AD - First Ward of Orthopedics Department, First Affiliated Hospital of Jiamusi University. FAU - Li, Yan-Bao AU - Li YB AD - Department of Orthopedics, Handan Central Hospital, Handan, China. LA - eng PT - Journal Article PL - United States TA - Medicine (Baltimore) JT - Medicine JID - 2985248R RN - 0 (Anti-Inflammatory Agents, Non-Steroidal) RN - WK2XYI10QM (Ibuprofen) SB - IM MH - Anti-Inflammatory Agents, Non-Steroidal/administration & dosage MH - China MH - Electric Stimulation Therapy/*methods MH - Female MH - *Femur Head Necrosis/diagnosis/physiopathology/therapy MH - Humans MH - Ibuprofen/*administration & dosage MH - Male MH - Middle Aged MH - *Pain/diagnosis/etiology MH - Pain Management/methods MH - Pain Measurement/methods MH - Retrospective Studies MH - Severity of Illness Index MH - Treatment Outcome PMC - PMC6426472 COIS- The authors have no conflicts of interest to disclose. EDAT- 2019/03/19 06:00 MHDA- 2019/04/04 06:00 PMCR- 2019/03/15 CRDT- 2019/03/19 06:00 PHST- 2019/03/19 06:00 [entrez] PHST- 2019/03/19 06:00 [pubmed] PHST- 2019/04/04 06:00 [medline] PHST- 2019/03/15 00:00 [pmc-release] AID - 00005792-201903150-00044 [pii] AID - MD-D-18-08821 [pii] AID - 10.1097/MD.0000000000014812 [doi] PST - ppublish SO - Medicine (Baltimore). 2019 Mar;98(11):e14812. doi: 10.1097/MD.0000000000014812.