PMID- 30887632
OWN - NLM
STAT- MEDLINE
DCOM- 20191203
LR  - 20210109
IS  - 1399-5618 (Electronic)
IS  - 1398-5647 (Print)
IS  - 1398-5647 (Linking)
VI  - 21
IP  - 3
DP  - 2019 May
TI  - Functional outcome assessment in bipolar disorder: A systematic literature 
      review.
PG  - 194-214
LID - 10.1111/bdi.12775 [doi]
AB  - OBJECTIVES: Functional impairment is an important driver of disability in 
      patients with bipolar disorder (BD) and can persist even when symptomatic 
      remission has been achieved. The objectives of this systematic literature review 
      were to identify studies that assessed functioning in patients with BD and 
      describe the functional scales used and their implementation. METHODS: A 
      systematic literature review of English-language articles published between 2000 
      and 2017 reporting peer-reviewed, original research related to functional 
      assessment in patients with BD was conducted. RESULTS: A total of 40 articles met 
      inclusion criteria. Twenty-four different functional scales were identified, 
      including 13 clinician-rated scales, 7 self-reported scales, and 4 indices based 
      on residential and vocational data. The Global Assessment of Functioning (GAF) 
      and the Functional Assessment Short Test (FAST) were the most commonly used 
      global and domain-specific scales, respectively. All other scales were used in </=2 
      studies. Most studies used >/=1 domain-specific scale. The most common applications 
      of functional scales in these studies were evaluations of the relationships 
      between global or domain-specific psychosocial functioning and cognitive 
      functioning (eg, executive function, attention, language, learning, memory) or 
      clinical variables (eg, symptoms, duration of illness, number of 
      hospitalizations, number of episodes). CONCLUSIONS: The results of this review 
      show growing interest in the assessment of functioning in patients with BD, with 
      an emphasis on specific domains such as work/educational, social, family, and 
      cognitive functioning and high utilization of the GAF and FAST scales in 
      published literature.
CI  - (c) 2019 The Authors. Bipolar Disorders Published by John Wiley & Sons Ltd.
FAU - Chen, Maxine
AU  - Chen M
AD  - Medical Affairs, Otsuka Pharmaceutical Development & Commercialization, Inc, 
      Princeton, New Jersey.
FAU - Fitzgerald, Heather M
AU  - Fitzgerald HM
AD  - Medical Affairs - Psychiatry, Lundbeck LLC, Deerfield, Illinois.
FAU - Madera, Jessica J
AU  - Madera JJ
AD  - Medical Affairs, Otsuka Pharmaceutical Development & Commercialization, Inc, 
      Princeton, New Jersey.
FAU - Tohen, Mauricio
AU  - Tohen M
AUID- ORCID: 0000-0001-8049-4351
AD  - Department of Psychiatry & Behavioral Sciences, University of New Mexico, 
      Albuquerque, New Mexico.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Research Support, Non-U.S. Gov't
PT  - Systematic Review
DEP - 20190414
PL  - Denmark
TA  - Bipolar Disord
JT  - Bipolar disorders
JID - 100883596
SB  - IM
CIN - Bipolar Disord. 2019 Nov;21(7):662-663. PMID: 31400289
CIN - Bipolar Disord. 2020 Jun;22(4):411-412. PMID: 31724258
MH  - Adult
MH  - Attention
MH  - Bipolar Disorder/*psychology
MH  - *Cognition
MH  - Cognition Disorders/diagnosis
MH  - Executive Function
MH  - Female
MH  - Humans
MH  - Male
MH  - Memory
MH  - Middle Aged
MH  - Neuropsychological Tests
MH  - Outcome Assessment, Health Care
MH  - Young Adult
PMC - PMC6593429
OTO - NOTNLM
OT  - bipolar disorder
OT  - cognitive function
OT  - neuropsychological tests
OT  - patient outcome assessment
OT  - patient-reported outcome measures
OT  - psychosocial factors
OT  - social adjustment
COIS- Maxine Chen and Jessica J. Madera are employees of Otsuka Pharmaceutical 
      Development & Commercialization, Inc. Heather M. Fitzgerald is an employee of 
      Lundbeck LLC. Mauricio Tohen was an employee of Eli Lilly (1997-2008) and has 
      received honoraria from or consulted for Abbott, AstraZeneca, Alkermes, Allergan, 
      Bristol Myers Squibb, GlaxoSmithKline, Eli Lilly, Johnson & Johnson, Otsuka, 
      Merck, Sunovion, Forest, Roche, Elan, Lundbeck, Teva, Pamlab, Minerva, Pfizer, 
      Wyeth, and Wiley Publishing; his spouse was a full-time employee at Eli Lilly 
      (1998-2013).
EDAT- 2019/03/20 06:00
MHDA- 2019/12/04 06:00
PMCR- 2019/06/26
CRDT- 2019/03/20 06:00
PHST- 2019/03/20 06:00 [pubmed]
PHST- 2019/12/04 06:00 [medline]
PHST- 2019/03/20 06:00 [entrez]
PHST- 2019/06/26 00:00 [pmc-release]
AID - BDI12775 [pii]
AID - 10.1111/bdi.12775 [doi]
PST - ppublish
SO  - Bipolar Disord. 2019 May;21(3):194-214. doi: 10.1111/bdi.12775. Epub 2019 Apr 14.