PMID- 30899335
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 1863-8880 (Print)
IS  - 1863-8899 (Electronic)
IS  - 1863-8880 (Linking)
VI  - 12
IP  - 8
DP  - 2018 Aug
TI  - Single-Shot Optical Anisotropy Imaging with Quantitative Polarization 
      Interference Microscopy.
LID - 1800070 [pii]
LID - 10.1002/lpor.201800070 [doi]
AB  - Optical anisotropy measurement is essential for material characterization and 
      biological imaging. In order to achieve single-shot mapping of the birefringence 
      parameters of anisotropic samples, a novel polarized light imaging concept is 
      proposed, namely quantitative polarization interference microscopy (QPIM). QPIM 
      can be realized through designing a compact polarization-resolved interference 
      microscopy system that captures interferograms bearing sample's linear 
      birefringence information. To extract the retardance and the orientation angle 
      maps from a single-shot measurement, a mathematical model for QPIM is further 
      developed. The QPIM system is validated by measuring a calibrated quarter-wave 
      plate, whose fast-axis orientation angle and retardance are determined with great 
      accuracies. The single-shot nature of QPIM further allows to measure the 
      transient dynamics of birefringence changes in material containing anisotropic 
      structures. This application is demonstrated by capturing transient retardance 
      changes in a custom-designed parallel-aligned nematic liquid crystal-based 
      device.
FAU - Ge, Baoliang
AU  - Ge B
AUID- ORCID: 0000-0002-1792-8871
AD  - Department of Mechanical Engineering Massachusetts Institute of Technology 
      Cambridge, MA 02139, USA, Department of Biological Engineering Massachusetts 
      Institute of Technology Cambridge, MA 02139, USA, Laser Biomedical Research 
      Center Massachusetts Institute of Technology Cambridge, MA 02139, USA.
FAU - Zhou, Renjie
AU  - Zhou R
AD  - Department of Biomedical Engineering The Chinese University of Hong Kong Shatin, 
      New Territories, Hong Kong SAR, China, rjzhou@cuhk.edu.hk.
FAU - Takiguchi, Yu
AU  - Takiguchi Y
AD  - Central Research Laboratory Hamamatsu Photonics K.K Hamamatsu, Shizuoka 434-8601, 
      Japan.
FAU - Yaqoob, Zahid
AU  - Yaqoob Z
AD  - Laser Biomedical Research Center Massachusetts Institute of Technology Cambridge, 
      MA 02139, USA, zyaqoob@mit.edu.
FAU - So, Peter T C
AU  - So PTC
AD  - Department of Mechanical Engineering Massachusetts Institute of Technology 
      Cambridge, MA 02139, USA, Department of Biological Engineering Massachusetts 
      Institute of Technology Cambridge, MA 02139, USA, Laser Biomedical Research 
      Center Massachusetts Institute of Technology Cambridge, MA 02139, USA.
LA  - eng
GR  - DP3 DK101024/DK/NIDDK NIH HHS/United States
GR  - R01 HL121386/HL/NHLBI NIH HHS/United States
GR  - R21 NS091982/NS/NINDS NIH HHS/United States
GR  - R01 EY017656/EY/NEI NIH HHS/United States
GR  - U01 CA202177/CA/NCI NIH HHS/United States
GR  - U01 NS090438/NS/NINDS NIH HHS/United States
GR  - P41 EB015871/EB/NIBIB NIH HHS/United States
PT  - Journal Article
DEP - 20180610
PL  - Germany
TA  - Laser Photon Rev
JT  - Laser & photonics reviews
JID - 101513682
PMC - PMC6424346
MID - NIHMS1017182
OTO - NOTNLM
OT  - instrumentation
OT  - interference microscopy
OT  - measurement and metrology
OT  - microscopy
OT  - polarimetric imaging
COIS- Conflict of Interest The authors declare no conflict of interest.
EDAT- 2019/03/23 06:00
MHDA- 2019/03/23 06:01
PMCR- 2019/03/19
CRDT- 2019/03/23 06:00
PHST- 2019/03/23 06:00 [entrez]
PHST- 2019/03/23 06:00 [pubmed]
PHST- 2019/03/23 06:01 [medline]
PHST- 2019/03/19 00:00 [pmc-release]
AID - 1800070 [pii]
AID - 10.1002/lpor.201800070 [doi]
PST - ppublish
SO  - Laser Photon Rev. 2018 Aug;12(8):1800070. doi: 10.1002/lpor.201800070. Epub 2018 
      Jun 10.