PMID- 30903878 OWN - NLM STAT- MEDLINE DCOM- 20190808 LR - 20190808 IS - 1090-2414 (Electronic) IS - 0147-6513 (Linking) VI - 175 DP - 2019 Jul 15 TI - Examining the role of total organic carbon and black carbon in the fate of legacy persistent organic pollutants (POPs) in indoor dust from Nepal: Implication on human health. PG - 225-235 LID - S0147-6513(19)30310-0 [pii] LID - 10.1016/j.ecoenv.2019.03.048 [doi] AB - Despite the fact that the consumption and import of legacy persistent organic pollutants (POPs) have been stopped in Nepal since 2001, they are still of worry for human prosperity and the environment because of their persistence behavior and constant release from sources that are presently being used. The essential objective of this study was to assess the concentration and spatial distribution of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in residential dust from Nepal keeping in mind the end goal to evaluate the importance of total organic carbon (TOC) and black carbon (BC) in the fate of legacy POPs. Additionally, health risk exposure via dust ingestion and dermal absorption was estimated to evaluate the significance of dust media for human exposure. Results demonstrated that summation operatorOCPs in dust was 37 times greater than summation operatorPCBs. DDT was mostly dominated in the dust, and contributed 90% of the summation operatorOCPs, while hexa-CBs predominated among PCBs and represented 34% of summation operatorPCBs. Birgunj and Biratnagar had a relatively higher level of summation operatorOCPs and summation operatorPCBs than those of Kathmandu and Pokhara. TOC and BC showed a poor connection with OCPs, recommending little or no role. However, PCB in the dust, especially low congeners was strongly linked with TOC but not BC indicating the significant role of TOC. The daily risk exposure estimation indicated dermal absorption through dust as the principal means of OCPs/PCBs intake to both adult and children population. These estimated exposures were 2-4 orders of magnitude inferior to their corresponding reference dose showing insignificant risk. CI - Copyright (c) 2019 Elsevier Inc. All rights reserved. FAU - Chandra Yadav, Ishwar AU - Chandra Yadav I AD - State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, 510640, PR China; Department of International Environmental and Agricultural Science (IEAS), Tokyo University of Agriculture and Technology (TUAT) 3-5-8, Saiwai-Cho, Fuchu-Shi, Tokyo, 1838509, Japan. Electronic address: icyadav.bhu@gmail.com. FAU - Devi, Ningombam Linthoingambi AU - Devi NL AD - Centre for Environmental Sciences, Central University of South Bihar, SH-7, Gaya-Panchanpur, Post-Fatehpur, P.S-Tekari, District-Gaya, 824236, Bihar, India. FAU - Li, Jun AU - Li J AD - State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, 510640, PR China. FAU - Zhang, Gan AU - Zhang G AD - State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, 510640, PR China. LA - eng PT - Journal Article DEP - 20190320 PL - Netherlands TA - Ecotoxicol Environ Saf JT - Ecotoxicology and environmental safety JID - 7805381 RN - 0 (Air Pollutants) RN - 0 (Dust) RN - 0 (Hydrocarbons) RN - 0 (Hydrocarbons, Chlorinated) RN - 0 (Pesticides) RN - 0 (Soot) RN - DFC2HB4I0K (Polychlorinated Biphenyls) MH - Adult MH - Air Pollutants/*analysis MH - Air Pollution, Indoor/*analysis MH - Child MH - Dust/*analysis MH - Environmental Monitoring/*methods MH - Housing/standards MH - Humans MH - Hydrocarbons/*analysis MH - Hydrocarbons, Chlorinated/analysis MH - Nepal MH - Pesticides/analysis MH - Polychlorinated Biphenyls/analysis MH - Soot/*analysis OTO - NOTNLM OT - Dermal absorption OT - Dust ingestion OT - Lindane OT - Nepal OT - Technical DDT OT - Urban area EDAT- 2019/03/25 06:00 MHDA- 2019/08/09 06:00 CRDT- 2019/03/24 06:00 PHST- 2018/11/09 00:00 [received] PHST- 2019/03/06 00:00 [revised] PHST- 2019/03/12 00:00 [accepted] PHST- 2019/03/25 06:00 [pubmed] PHST- 2019/08/09 06:00 [medline] PHST- 2019/03/24 06:00 [entrez] AID - S0147-6513(19)30310-0 [pii] AID - 10.1016/j.ecoenv.2019.03.048 [doi] PST - ppublish SO - Ecotoxicol Environ Saf. 2019 Jul 15;175:225-235. doi: 10.1016/j.ecoenv.2019.03.048. Epub 2019 Mar 20.