PMID- 30906387 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220408 IS - 2384-0757 (Electronic) IS - 1738-1495 (Print) IS - 1738-1495 (Linking) VI - 17 IP - 1 DP - 2018 Mar TI - Re-standardization of the Korean-Instrumental Activities of Daily Living (K-IADL): Clinical Usefulness for Various Neurodegenerative Diseases. PG - 11-22 LID - 10.12779/dnd.2018.17.1.11 [doi] AB - BACKGROUND AND PURPOSE: Evaluating instrumental activities of daily living (IADL) is an important part of procedure to diagnose dementia. The Korean-Instrumental Activities of Daily Living (K-IADL) has been used extensively in Korea. However, its cut-off score has not been reformulated since 2002. The purpose of this study was to yield a new optimal cut-off score for the K-IADL and confirm the validity of this new cut-off score with various dementia groups. METHODS: We retrospectively collected a total of 2,347 patients' K-IADL data from 6 general hospitals in Korea. These patients had mild cognitive impairment (MCI) or dementia with various etiologies for cognitive impairment. We also recruited a normal control group (n=254) from the community. Korean-Mini Mental State Examination, Short version of the Geriatric Depression Scale, Clinical Dementia Rating, and Global Deterioration Scale were administered to all participants. Caregivers completed K-IADL and Barthel Index. RESULTS: K-IADL scores were significantly different among dementia subgroups, but not significantly different among MCI subgroups. Based on internal consistency, correlations with other scales, and factor analysis, K-IADL showed excellent reliability and validity. The new optimal cut-off score to diagnose dementia was 0.40, which gave a sensitivity of 0.901 and a specificity of 0.916. Positive predictive value for dementia using the new cut-off score was 94.2% for Alzheimer's disease, 100% for vascular dementia, and 84% for Parkinson's disease. CONCLUSIONS: Our results illustrate that the new K-IADL cut-off score of 0.40 is reliable and valid for screening impairments of daily functioning resulting from various etiologies. FAU - Chin, Juhee AU - Chin J AD - Department of Neurology, Samsung Medical Center, Seoul, Korea. FAU - Park, Jaeseol AU - Park J AD - Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea. FAU - Yang, Soh-Jeong AU - Yang SJ AD - Department of Neurology, Yonsei University Health System, Seoul, Korea. FAU - Yeom, Jiyoung AU - Yeom J AD - Department of Neurology, Ewha Womans University Mokdong Hospital, Ewha Womans University School of Medicine, Seoul, Korea. FAU - Ahn, Yisuh AU - Ahn Y AD - The BOM Brain Health Neuropsychology Center and Cognitive Rehabilitation Research Institute, Seoul, Korea. FAU - Baek, Min Jae AU - Baek MJ AD - Cognitive Neuroscience Center, Seoul National University Bundang Hospital, Seongnam, Korea. FAU - Ryu, Hui Jin AU - Ryu HJ AD - Department of Neurology, Konkuk University Medical Center, Seoul, Korea. FAU - Lee, Byung Hwa AU - Lee BH AD - Department of Neurology, Samsung Medical Center, Seoul, Korea. FAU - Han, Noh Eul AU - Han NE AD - Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. FAU - Ryu, Kyung Hi AU - Ryu KH AD - Human Brain Research & Consulting, Seoul, Korea. FAU - Kang, Yeonwook AU - Kang Y AD - Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea. AD - Department of Psychology, Hallym University, Chuncheon, Korea. LA - eng PT - Journal Article DEP - 20180331 PL - Korea (South) TA - Dement Neurocogn Disord JT - Dementia and neurocognitive disorders JID - 101600298 PMC - PMC6427997 OTO - NOTNLM OT - Activities of Daily Living OT - Dementia OT - Mild Cognitive Impairment COIS- Conflict of Interest: The authors have no financial conflicts of interest. EDAT- 2019/03/25 06:00 MHDA- 2019/03/25 06:01 PMCR- 2018/03/01 CRDT- 2019/03/26 06:00 PHST- 2017/12/29 00:00 [received] PHST- 2018/03/23 00:00 [revised] PHST- 2018/03/23 00:00 [accepted] PHST- 2019/03/26 06:00 [entrez] PHST- 2019/03/25 06:00 [pubmed] PHST- 2019/03/25 06:01 [medline] PHST- 2018/03/01 00:00 [pmc-release] AID - 10.12779/dnd.2018.17.1.11 [doi] PST - ppublish SO - Dement Neurocogn Disord. 2018 Mar;17(1):11-22. doi: 10.12779/dnd.2018.17.1.11. Epub 2018 Mar 31.