PMID- 30917433 OWN - NLM STAT- MEDLINE DCOM- 20190425 LR - 20190425 IS - 0578-1426 (Print) IS - 0578-1426 (Linking) VI - 58 IP - 4 DP - 2019 Apr 1 TI - [The 469th case: multiple cutaneous abscesses, pelvic mass, and lung cavities]. PG - 333-336 LID - 10.3760/cma.j.issn.0578-1426.2019.04.021 [doi] AB - A 28-year-old woman with multiple abscesses for 2 month and fever for 1 month was admitted in Peking Union Medical College Hospital. The skin abscesses gradually developed at skull, face, abdominal wall and pelvis. Laboratory examinations related to inflammatory reactions were strongly high including erythrocyte sedimentation rate 99 mm/1 h,C-reactive protein160.28 mg/L and ferritin 1 584 mug/L. Multiple nodules and cavities were detected in lungs. And vesico-cervical fistula was found during exploratory laparotomy. The pathological tests of abdominal tissues demonstrated necrosis and granuloma. Evidence of infectious diseases was not definite. Positive anti-proteinase 3 (PR3) antibody confirmed the diagnosis of granulomatosis with polyangiitis. After treated with glucocorticoid and immunosuppressants, the patient's symptoms improved remarkably. This case suggested that systemic vasculitis should be considered as a differential diagnosis of multiple abscesses which are not explained by infections. FAU - Cao, X Y AU - Cao XY AD - Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China. FAU - Zhao, J L AU - Zhao JL AD - Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China. FAU - Zhou, Y Z AU - Zhou YZ AD - Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China. FAU - Zhou, B T AU - Zhou BT AD - Department of Infectious Diseases, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China. FAU - Wu, Q J AU - Wu QJ AD - Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China. FAU - Zeng, X F AU - Zeng XF AD - Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China. LA - chi PT - Case Reports PT - Journal Article PL - China TA - Zhonghua Nei Ke Za Zhi JT - Zhonghua nei ke za zhi JID - 16210490R RN - 0 (Immunosuppressive Agents) SB - IM MH - *Abscess MH - Adult MH - Blood Sedimentation MH - Diagnosis, Differential MH - Female MH - Humans MH - Immunosuppressive Agents MH - Lung Diseases MH - *Skin MH - Skin Diseases OTO - NOTNLM OT - Fever OT - Granulomatosis with polyangiitis OT - Multiple abscess EDAT- 2019/03/29 06:00 MHDA- 2019/04/26 06:00 CRDT- 2019/03/28 06:00 PHST- 2019/03/28 06:00 [entrez] PHST- 2019/03/29 06:00 [pubmed] PHST- 2019/04/26 06:00 [medline] AID - 10.3760/cma.j.issn.0578-1426.2019.04.021 [doi] PST - ppublish SO - Zhonghua Nei Ke Za Zhi. 2019 Apr 1;58(4):333-336. doi: 10.3760/cma.j.issn.0578-1426.2019.04.021.