PMID- 30934201
OWN - NLM
STAT- MEDLINE
DCOM- 20190425
LR  - 20190425
IS  - 0578-1310 (Print)
IS  - 0578-1310 (Linking)
VI  - 57
IP  - 4
DP  - 2019 Apr 2
TI  - [A long-term follow-up study of cardiac resynchronization therapy for children 
      with right ventricle-paced heart failure].
PG  - 281-285
LID - 10.3760/cma.j.issn.0578-1310.2019.04.010 [doi]
AB  - Objective: To evaluate the long-term effects of cardiac resynchronization therapy 
      (CRT) in children with right ventricle-paced heart failure. Methods: Five 
      children with chronically right ventricular-paced heart failure underwent 
      operation of upgrading to CRT in Guangdong Cardiovascular Institute between July 
      2009 to January 2015. The first time the patients were implanted with endocardial 
      permanent pacemaker was (11.6+/-4.6) years old. The New York Heart Association 
      (NYHA) functional classification, QRS duration, left ventricular end diastolic 
      diameter (LVDd), left ventricular ejection fraction (LVEF), standard deviation of 
      peak systolic time of left ventricular wall (TS-SD) and follow-up data were 
      retrospectively analyzed. Comparison between pre-and post-operation was performed 
      using paired t test. Results: CRT significantly improved the NYHA class to 
      Ⅰ-Ⅱdegree, reduced the QRS duration ((126+/-9)vs. (182+/-21)ms, t=-7.480, P=0.002) 
      and the Z-score of LVDd (2.8+/-1.1 vs. 4.7+/-0.9, t=-2.880, P=0.045), and increased 
      the LVEF (43%+/-10% vs. 28%+/-6%, t=3.350, P=0.029). No significant difference was 
      found regarding the TS-SD ((48+/-17)vs. (95+/-41)ms, t=-2.240, P=0.090) pre- and 
      post-CRT. The longest follow-up period was 9 years. During follow-up, 1 case died 
      of ventricular fibrillation 2 years after upgrading, and 2 cases underwent CRT 
      replacement due to battery depletion 7.2 years and 5.8 years after upgrading, 
      respectively. Conclusion: CRT could be considered for children with chronically 
      right ventricular-paced heart failure and improve heart function significantly.
FAU - Liu, T
AU  - Liu T
AD  - Department of Pediatric Cardiology, Guangdong Cardiovascular Institute, Guangdong 
      Provincial Key Laboratory of South China Structural Heart Disease, Guangdong 
      General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510800, China.
FAU - Liang, D P
AU  - Liang DP
FAU - Zhang, Z W
AU  - Zhang ZW
FAU - Wang, S S
AU  - Wang SS
FAU - Li, Y F
AU  - Li YF
FAU - Zhong, C Y
AU  - Zhong CY
FAU - Zeng, S Y
AU  - Zeng SY
LA  - chi
PT  - Journal Article
PL  - China
TA  - Zhonghua Er Ke Za Zhi
JT  - Zhonghua er ke za zhi = Chinese journal of pediatrics
JID - 0417427
SB  - IM
MH  - Adolescent
MH  - *Cardiac Resynchronization Therapy
MH  - Child
MH  - Follow-Up Studies
MH  - *Heart Failure
MH  - Heart Ventricles
MH  - Humans
MH  - Retrospective Studies
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Cardiac resynchronization therapy
OT  - Child
OT  - Heart failure
EDAT- 2019/04/03 06:00
MHDA- 2019/04/26 06:00
CRDT- 2019/04/03 06:00
PHST- 2019/04/03 06:00 [entrez]
PHST- 2019/04/03 06:00 [pubmed]
PHST- 2019/04/26 06:00 [medline]
AID - 10.3760/cma.j.issn.0578-1310.2019.04.010 [doi]
PST - ppublish
SO  - Zhonghua Er Ke Za Zhi. 2019 Apr 2;57(4):281-285. doi: 
      10.3760/cma.j.issn.0578-1310.2019.04.010.