PMID- 30934572
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 2305-6304 (Electronic)
IS  - 2305-6304 (Linking)
VI  - 7
IP  - 1
DP  - 2019 Mar 25
TI  - Propensity of Tagetes erecta L., a Medicinal Plant Commonly Used in Diabetes 
      Management, to Accumulate Perfluoroalkyl Substances.
LID - 10.3390/toxics7010018 [doi]
LID - 18
AB  - It has been extensively demonstrated that plants accumulate organic substances 
      emanating from various sources, including soil and water. This fact suggests the 
      potentiality of contamination of certain vital bioresources, such as medicinal 
      plants, by persistent contaminants, such as perfluorooctanoic acid (PFOA), 
      perfluorooctane sulfonate (PFOS), and perfluorobutane sulfonate (PFBS). Hence, in 
      this study, the propensity of Tagetes erecta L. (a commonly used medicinal plant) 
      to accumulate PFOA, PFOS, and PFBS was determined using liquid 
      chromatography/tandem mass spectrometry (LC(-)MS/MS-8030). From the results, PFOA, 
      PFOS, and PFBS were detected in all the plant samples and concentration levels 
      were found to be 94.83 ng/g, 5.03 ng/g, and 1.44 ng/g, respectively, with 
      bioconcentration factor (BCF) ranges of 1.30 to 2.57, 13.67 to 72.33, and 0.16 to 
      0.31, respectively. Little evidence exists on the bioaccumulative susceptibility 
      of medicinal plants to these persistent organic pollutants (POPs). These results 
      suggest that these medicinal plants (in particular, Tagetes erecta L., used for 
      the management of diabetes) are also potential conduits of PFOA, PFOS, and PFBS 
      into humans.
FAU - Mudumbi, John Baptist Nzukizi
AU  - Mudumbi JBN
AUID- ORCID: 0000-0002-2743-1324
AD  - Bioresource Engineering Research Group (BioERG), Department of Biotechnology and 
      Consumer Sciences, Cape Peninsula University of Technology, PO Box 652, Cape Town 
      8000, Western Cape, South Africa. jbmudumbi@gmail.com.
FAU - Daso, Adegbenro Peter
AU  - Daso AP
AUID- ORCID: 0000-0002-8019-0590
AD  - Department of Environmental, Water and Earth Sciences, Faculty of Science, 
      Tshwane University of Technology, Pretoria 0083, South Africa. 
      adegbenrop@gmail.com.
FAU - Okonkwo, Okechukwu Jonathan
AU  - Okonkwo OJ
AD  - Department of Environmental, Water and Earth Sciences, Faculty of Science, 
      Tshwane University of Technology, Pretoria 0083, South Africa. 
      OkonkwoOJ@tut.ac.za.
FAU - Ntwampe, Seteno Karabo Obed
AU  - Ntwampe SKO
AUID- ORCID: 0000-0001-7516-6249
AD  - Bioresource Engineering Research Group (BioERG), Department of Biotechnology and 
      Consumer Sciences, Cape Peninsula University of Technology, PO Box 652, Cape Town 
      8000, Western Cape, South Africa. NtwampeS@cput.ac.za.
FAU - Matsha, Tandi E
AU  - Matsha TE
AD  - Department of Bio-Medical Sciences, Faculty of Health and Wellness Science, Cape 
      Peninsula University of Technology, PO Box 1906, Bellville 7535, Western Cape, 
      South Africa. MATSHAT@cput.ac.za.
FAU - Mekuto, Lukhanyo
AU  - Mekuto L
AUID- ORCID: 0000-0003-3069-4624
AD  - Department of Chemical Engineering, University of Johannesburg, PO Box 17011, 
      Johannesburg 2028, Gauteng, South Africa. lukhayo.mekuto@gmail.com.
FAU - Itoba-Tombo, Elie Fereche
AU  - Itoba-Tombo EF
AD  - Bioresource Engineering Research Group (BioERG), Department of Biotechnology and 
      Consumer Sciences, Cape Peninsula University of Technology, PO Box 652, Cape Town 
      8000, Western Cape, South Africa. elie.tombo@gmail.com.
FAU - Adetunji, Adewole T
AU  - Adetunji AT
AUID- ORCID: 0000-0001-5565-3605
AD  - Department of Agriculture, Cape Peninsula University of Technology, Wellington 
      Campus, Wellington 7655, Western Cape, South Africa. adetunjiadewole@gmail.com.
FAU - Sibali, Linda L
AU  - Sibali LL
AD  - Research Management Unit, Faculty of Applied Sciences, Cape Peninsula University 
      of Technology, PO Box 652, Cape Town 8000, Western Cape, South Africa. 
      SibaliL@cput.ac.za.
LA  - eng
GR  - 99843/National Research Foundation/
PT  - Journal Article
DEP - 20190325
PL  - Switzerland
TA  - Toxics
JT  - Toxics
JID - 101639637
PMC - PMC6468628
OTO - NOTNLM
OT  - Tagetes erecta L.
OT  - medicinal plants
OT  - perfluoroalkyl substances (PFASs)
OT  - perfluorobutane sulfonate (PFBS)
OT  - perfluorooctane sulfonate (PFOS)
OT  - perfluorooctanoic acid (PFOA)
COIS- The authors declare no conflict of interest.
EDAT- 2019/04/03 06:00
MHDA- 2019/04/03 06:01
PMCR- 2019/03/25
CRDT- 2019/04/03 06:00
PHST- 2019/01/26 00:00 [received]
PHST- 2019/02/16 00:00 [revised]
PHST- 2019/02/26 00:00 [accepted]
PHST- 2019/04/03 06:00 [entrez]
PHST- 2019/04/03 06:00 [pubmed]
PHST- 2019/04/03 06:01 [medline]
PHST- 2019/03/25 00:00 [pmc-release]
AID - toxics7010018 [pii]
AID - toxics-07-00018 [pii]
AID - 10.3390/toxics7010018 [doi]
PST - epublish
SO  - Toxics. 2019 Mar 25;7(1):18. doi: 10.3390/toxics7010018.