PMID- 30937080
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220408
IS  - 1817-1745 (Print)
IS  - 1998-3948 (Electronic)
IS  - 1817-1745 (Linking)
VI  - 13
IP  - 4
DP  - 2018 Oct-Dec
TI  - Benign Acute Childhood Myositis: A Benign Disease that Mimics More Severe 
      Neuromuscular Disorder.
PG  - 404-409
LID - 10.4103/JPN.JPN_116_18 [doi]
AB  - CONTEXT: Proximal lower limb weakness presenting acutely with or without 
      preceding fever is a strong mimic of Guillain-Barre syndrome (GBS). Benign acute 
      childhood myositis (BACM) forms an important differential diagnosis in such 
      cases. AIM: To characterize the clinical and laboratory findings of patients with 
      BACM for better understanding of the disease. SETTINGS AND DESIGN: This 
      prospective longitudinal study was conducted in a tertiary care hospital of 
      northern India. MATERIALS AND METHODS: Thirty-two patients presenting in the 
      outpatient or emergency clinic of the hospital with severe myalgia that 
      exacerbated with straight leg raising test and fever from July 2016 to July 2017 
      were included in the study. STATISTICAL ANALYSIS: All the continuous data were 
      expressed as number and percentage or mean +/- standard deviation/median. 
      Non-parametric continuous data between groups were analyzed by Friedman's test. 
      RESULTS: The mean age of the patients was 14.3 (+/-8.7) years and they presented 
      after a nonspecific febrile illness in most of the cases (53.1%). The symptoms 
      resolved after a mean of 5.7 (+/-1.6) days. Myalgia was present in 21 (65%) cases, 
      whereas proximal weakness was the prominent finding in 14 (43%) cases. 
      Electrolyte abnormality (hypokalemia) was present in four (12.5%) cases. In all 
      patients, the muscle enzymes (creatine phosphokinase, serum glutamic oxaloacetic 
      transaminase, serum glutamic pyruvic transaminase, and lactate dehydrogenase) 
      were elevated at presentation, and electromyography showed myopathic pattern. A 
      significant recovery took place in the next 5-7 days. CONCLUSION: BACM should be 
      actively looked for in cases of painful acute proximal limb weakness in the 
      adolescents.
FAU - Pradhan, Sunil
AU  - Pradhan S
AD  - Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical 
      Sciences, Lucknow, Uttar Pradesh, India.
FAU - Das, Animesh
AU  - Das A
AD  - Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical 
      Sciences, Lucknow, Uttar Pradesh, India.
FAU - Anand, Sucharita
AU  - Anand S
AD  - Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical 
      Sciences, Lucknow, Uttar Pradesh, India.
LA  - eng
PT  - Journal Article
PL  - India
TA  - J Pediatr Neurosci
JT  - Journal of pediatric neurosciences
JID - 101273794
PMC - PMC6413614
OTO - NOTNLM
OT  - Benign
OT  - creatine phosphokinase
OT  - electromyography
OT  - myositis
COIS- There are no conflicts of interest.
EDAT- 2019/04/03 06:00
MHDA- 2019/04/03 06:01
PMCR- 2018/10/01
CRDT- 2019/04/03 06:00
PHST- 2019/04/03 06:00 [entrez]
PHST- 2019/04/03 06:00 [pubmed]
PHST- 2019/04/03 06:01 [medline]
PHST- 2018/10/01 00:00 [pmc-release]
AID - JPN-13-404 [pii]
AID - 10.4103/JPN.JPN_116_18 [doi]
PST - ppublish
SO  - J Pediatr Neurosci. 2018 Oct-Dec;13(4):404-409. doi: 10.4103/JPN.JPN_116_18.