PMID- 30944542 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200930 IS - 1340-3516 (Print) IS - 1347-7501 (Electronic) IS - 1340-3516 (Linking) VI - 30 IP - 1 DP - 2019 Mar TI - Markers for oxidative stress in the synovial fluid of Thoroughbred horses with carpal bone fracture. PG - 13-16 LID - 10.1294/jes.30.13 [doi] AB - Arthritis is thought to cause oxidative stress in synovial fluid in humans, but there have been few reports in horses. To evaluate oxidative stress in synovial fluid in horses, this study used 19 horses with unilateral fracture of the carpal joint bone. Synovial fluid was collected from the carpal joint on the fracture (arthritis group) and contralateral (control group) sides. Diacron-reactive oxygen metabolites (d-ROMs) and biological antioxidant potential (BAP) were then measured, and the oxidative stress index (OSI) was calculated. d-ROMs and OSI of the arthritis group were significantly higher than the control group. BAP of the arthritis group was significantly lower than the control group. Thus, this study revealed that oxidative stress develops in the synovial fluid of horses during arthritis. FAU - Tsuzuki, Nao AU - Tsuzuki N AD - Obihiro University of Agriculture and Veterinary Medicine, Hokkaido 080-8555, Japan. FAU - Kanbayashi, Yoshinori AU - Kanbayashi Y AD - Racehorse Hospital, Miho Training Center, Japan Racing Association, Ibaraki 300-0493, Japan. FAU - Kusano, Kanichi AU - Kusano K AD - Racehorse Hospital, Miho Training Center, Japan Racing Association, Ibaraki 300-0493, Japan. LA - eng PT - Journal Article DEP - 20190403 PL - Japan TA - J Equine Sci JT - Journal of equine science JID - 9503751 PMC - PMC6445753 OTO - NOTNLM OT - arthritis OT - horse OT - oxidative stress OT - synovial fluid EDAT- 2019/04/05 06:00 MHDA- 2019/04/05 06:01 PMCR- 2019/03/01 CRDT- 2019/04/05 06:00 PHST- 2018/02/19 00:00 [received] PHST- 2018/11/26 00:00 [accepted] PHST- 2019/04/05 06:00 [entrez] PHST- 2019/04/05 06:00 [pubmed] PHST- 2019/04/05 06:01 [medline] PHST- 2019/03/01 00:00 [pmc-release] AID - 1810 [pii] AID - 10.1294/jes.30.13 [doi] PST - ppublish SO - J Equine Sci. 2019 Mar;30(1):13-16. doi: 10.1294/jes.30.13. Epub 2019 Apr 3.