PMID- 30949077
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 1664-0640 (Print)
IS  - 1664-0640 (Electronic)
IS  - 1664-0640 (Linking)
VI  - 10
DP  - 2019
TI  - A Review of 3,4-methylenedioxymethamphetamine (MDMA)-Assisted Psychotherapy.
PG  - 138
LID - 10.3389/fpsyt.2019.00138 [doi]
LID - 138
AB  - This paper provides a brief review of the history, proposed pharmacological 
      mechanisms, safety issues, and clinical applications of the medicine 
      3,4-methylenedioxymethamphetamine (MDMA). Most clinical MDMA research in patients 
      to date has focused on MDMA-assisted psychotherapy to treat posttraumatic stress 
      disorder (PTSD). In this review paper other potential therapeutic applications 
      for MDMA therapy are described, including contemporary studies treating anxiety 
      associated with autism and the authors' ongoing study exploring the potential 
      role for MDMA-assisted psychotherapy to treat alcohol use disorder. MDMA therapy 
      for PTSD is now entering the final Phase 3 stage of drug development, with a 
      target set for licensing by the FDA and EMA in 2021. This means that if clinical 
      efficacy criteria are achieved, MDMA would become a medicine.
FAU - Sessa, Ben
AU  - Sessa B
AD  - Neuropsychopharmacology Unit, Department of Medicine, Imperial College London, 
      London, United Kingdom.
FAU - Higbed, Laurie
AU  - Higbed L
AD  - Neuropsychopharmacology Unit, Department of Medicine, Imperial College London, 
      London, United Kingdom.
FAU - Nutt, David
AU  - Nutt D
AD  - Neuropsychopharmacology Unit, Department of Medicine, Imperial College London, 
      London, United Kingdom.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20190320
PL  - Switzerland
TA  - Front Psychiatry
JT  - Frontiers in psychiatry
JID - 101545006
PMC - PMC6435835
OTO - NOTNLM
OT  - 4-methylenedioxymethamphetamine)
OT  - MDMA (3
OT  - addiction
OT  - alcohol
OT  - psychotherapy
OT  - trauma
EDAT- 2019/04/06 06:00
MHDA- 2019/04/06 06:01
PMCR- 2019/03/20
CRDT- 2019/04/06 06:00
PHST- 2018/12/19 00:00 [received]
PHST- 2019/02/26 00:00 [accepted]
PHST- 2019/04/06 06:00 [entrez]
PHST- 2019/04/06 06:00 [pubmed]
PHST- 2019/04/06 06:01 [medline]
PHST- 2019/03/20 00:00 [pmc-release]
AID - 10.3389/fpsyt.2019.00138 [doi]
PST - epublish
SO  - Front Psychiatry. 2019 Mar 20;10:138. doi: 10.3389/fpsyt.2019.00138. eCollection 
      2019.